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Murcko scaffold

2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-phenylacetamide scaffold

48 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
48
With full pages
9
Scaffold SMILES

O=C(Nc1ccccc1)C(=O)c1cn(CC(=O)N2CCCC2)c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-phenylacetamide page
Murcko scaffold O=C(Nc1ccccc1)C(=O)c1cn(CC(=O)N2CCCC2)c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

N-(4-Fluorophenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C22H20FN3O3, CAS 872849-35-9
N-(4-Fluorophenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-35-9C22H20FN3O3
N-(2-Chlorophenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C22H20ClN3O3, CAS 872849-36-0
N-(2-Chlorophenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-36-0C22H20ClN3O3
N-(3-Chlorophenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C22H20ClN3O3, CAS 872849-37-1
N-(3-Chlorophenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-37-1C22H20ClN3O3
N-(4-Chlorophenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C22H20ClN3O3, CAS 872849-38-2
N-(4-Chlorophenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-38-2C22H20ClN3O3
N-(3-Bromophenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C22H20BrN3O3, CAS 872849-39-3
N-(3-Bromophenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872849-39-3C22H20BrN3O3
N-(4-Bromophenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C22H20BrN3O3, CAS 872849-40-6
N-(4-Bromophenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872849-40-6C22H20BrN3O3
N-(2-Methoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C23H23N3O4, CAS 872849-41-7
N-(2-Methoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-41-7C23H23N3O4
N-(3-Methoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C23H23N3O4, CAS 872849-42-8
N-(3-Methoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-42-8C23H23N3O4
N-(4-Methoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C23H23N3O4, CAS 872849-43-9
N-(4-Methoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-43-9C23H23N3O4
N-(2-Ethoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C24H25N3O4, CAS 872849-44-0
N-(2-Ethoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-44-0C24H25N3O4
N-(4-Ethoxyphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C24H25N3O4, CAS 872849-45-1
N-(4-Ethoxyphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872849-45-1C24H25N3O4
2-Oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}-N-[4-(trifluoromethoxy)phenyl]acetamide chemical structure, C23H20F3N3O4, CAS 872849-46-2
2-Oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}-N-[4-(trifluoromethoxy)phenyl]acetamide
CAS 872849-46-2C23H20F3N3O4
N-(2-Methylsulfanylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C23H23N3O3S, CAS 872849-47-3
N-(2-Methylsulfanylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872849-47-3C23H23N3O3S
N-(4-Acetylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C24H23N3O4, CAS 872849-48-4
N-(4-Acetylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872849-48-4C24H23N3O4
N-(3-Acetylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C24H23N3O4, CAS 872849-49-5
N-(3-Acetylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872849-49-5C24H23N3O4
Methyl 4-(2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamido)benzoate chemical structure, C24H23N3O5, CAS 872854-69-8
Methyl 4-(2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamido)benzoate
CAS 872854-69-8C24H23N3O5
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-phenylacetamide chemical structure, C22H21N3O3, CAS 872849-25-7
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-phenylacetamide
CAS 872849-25-7C22H21N3O3
N-(2-Methylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C23H23N3O3, CAS 872849-26-8
N-(2-Methylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872849-26-8C23H23N3O3
N-(3-Methylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C23H23N3O3, CAS 872849-27-9
N-(3-Methylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872849-27-9C23H23N3O3
N-(4-Methylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C23H23N3O3, CAS 872849-28-0
N-(4-Methylphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872849-28-0C23H23N3O3
N-(2-Ethylphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C24H25N3O3, CAS 872849-29-1
N-(2-Ethylphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-29-1C24H25N3O3
N-(4-Ethylphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C24H25N3O3, CAS 872849-30-4
N-(4-Ethylphenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-30-4C24H25N3O3
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-(4-propan-2-ylphenyl)acetamide chemical structure, C25H27N3O3, CAS 872849-31-5
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-(4-propan-2-ylphenyl)acetamide
CAS 872849-31-5C25H27N3O3
N-(2-Fluorophenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C22H20FN3O3, CAS 872849-33-7
N-(2-Fluorophenyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872849-33-7C22H20FN3O3