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Murcko scaffold

Ring system with 4 rings and 27 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
8
With full pages
0
Scaffold SMILES

O=C(Cc1ccccc1)Nc1ccc(-n2cnc3ccccc3c2=O)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)Nc1ccc(-n2cnc3ccccc3c2=O)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-[4-(2-Methyl-4-oxoquinazolin-3-yl)phenyl]-2-phenylacetamide chemical structure, C23H19N3O2, CAS 904279-17-0
N-[4-(2-Methyl-4-oxoquinazolin-3-yl)phenyl]-2-phenylacetamide
CAS 904279-17-0C23H19N3O2
2-(4-Methoxyphenyl)-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]acetamide chemical structure, C24H21N3O3, CAS 903262-42-0
2-(4-Methoxyphenyl)-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]acetamide
CAS 903262-42-0C24H21N3O3
2-(4-Chlorophenyl)-N-[2-methyl-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]acetamide chemical structure, C24H20ClN3O2, CAS 903329-24-8
2-(4-Chlorophenyl)-N-[2-methyl-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]acetamide
CAS 903329-24-8C24H20ClN3O2
2-(4-Fluorophenyl)-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]acetamide chemical structure, C23H18FN3O2, CAS 898455-30-6
2-(4-Fluorophenyl)-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]acetamide
CAS 898455-30-6C23H18FN3O2
N-[4-(2-Methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-2-phenylbutanamide chemical structure, C25H23N3O2, CAS 898455-16-8
N-[4-(2-Methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-2-phenylbutanamide
CAS 898455-16-8C25H23N3O2
N-(2-Methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)-2-phenylbutanamide chemical structure, C26H25N3O2, CAS 903329-51-1
N-(2-Methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)-2-phenylbutanamide
CAS 903329-51-1C26H25N3O2
2-(4-Ethoxyphenyl)-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)acetamide chemical structure, C26H25N3O3, CAS 903330-08-5
2-(4-Ethoxyphenyl)-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)acetamide
CAS 903330-08-5C26H25N3O3
icFSP1 chemical structure, C26H25N3O5, CAS 1115910-36-5
icFSP1
CAS 1115910-36-5C26H25N3O5