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Murcko scaffold

4,4a,5,6-Tetrahydro-2(3H)-naphthalenone scaffold

20 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
20
With full pages
3
Scaffold SMILES

O=C1C=C2C=CCCC2CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4,4a,5,6-Tetrahydro-2(3H)-naphthalenone page
Murcko scaffold O=C1C=C2C=CCCC2CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone chemical structure, C11H14O, CAS 34545-88-5
7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone
CAS 34545-88-5C11H14O
Bipolaroxin chemical structure, C15H18O4, CAS 100665-30-3
Bipolaroxin
CAS 100665-30-3C15H18O4
4a-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone chemical structure, C11H14O, CAS 10271-07-5
4a-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone
CAS 10271-07-5C11H14O
4,4a,5,6-Tetrahydro-2(3H)-naphthalenone chemical structure, C10H12O, CAS 34545-87-4
4,4a,5,6-Tetrahydro-2(3H)-naphthalenone
CAS 34545-87-4C10H12O
5-Acetyl-4a-methyl-3,4,5,6-tetrahydronaphthalen-2-one chemical structure, C13H16O2, CAS 6816-50-8
5-Acetyl-4a-methyl-3,4,5,6-tetrahydronaphthalen-2-one
CAS 6816-50-8C13H16O2
4,4a,5,6-Tetrahydro-7-isopropyl-4,4a-dimethylnaphthalene-2(3H)-one chemical structure, C15H22O, CAS 93840-79-0
4,4a,5,6-Tetrahydro-7-isopropyl-4,4a-dimethylnaphthalene-2(3H)-one
CAS 93840-79-0C15H22O
4,4a,5,6-Tetrahydro-6-isopropyl-4,4a-dimethylnaphthalene-2(3H)-one chemical structure, C15H22O, CAS 94201-75-9
4,4a,5,6-Tetrahydro-6-isopropyl-4,4a-dimethylnaphthalene-2(3H)-one
CAS 94201-75-9C15H22O
Emeremophiline chemical structure, C27H36O6, CAS 312624-82-1
Emeremophiline
CAS 312624-82-1C27H36O6
Dendryphiellin C chemical structure, C21H28O4, CAS 121661-41-4
Dendryphiellin C
CAS 121661-41-4C21H28O4
7-Hydroxy-2,3,4,4a,5,6-hexahydronaphthalen-2-one chemical structure, C10H12O2, CAS 1614-83-1
7-Hydroxy-2,3,4,4a,5,6-hexahydronaphthalen-2-one
CAS 1614-83-1C10H12O2
4,4a,5,6-Tetrahydro-7-methoxy-2(3H)-naphthalenone chemical structure, C11H14O2, CAS 1614-84-2
4,4a,5,6-Tetrahydro-7-methoxy-2(3H)-naphthalenone
CAS 1614-84-2C11H14O2
(4aS)-4a-Methyl-3,4,5,6-tetrahydronaphthalen-2-one chemical structure, C11H14O, CAS 106111-99-3
(4aS)-4a-Methyl-3,4,5,6-tetrahydronaphthalen-2-one
CAS 106111-99-3C11H14O
(4aR)-4,4a,5,6-Tetrahydro-4a-methyl-2(3H)-naphthalenone chemical structure, C11H14O, CAS 119489-83-7
(4aR)-4,4a,5,6-Tetrahydro-4a-methyl-2(3H)-naphthalenone
CAS 119489-83-7C11H14O
Dendryphiellin D chemical structure, C21H28O5, CAS 121678-87-3
Dendryphiellin D
CAS 121678-87-3C21H28O5
Dendryphiellin A chemical structure, C21H28O5, CAS 113592-81-7
Dendryphiellin A
CAS 113592-81-7C21H28O5
8-Methyl-4,4a,5,6-tetrahydronaphthalen-2(3H)-one chemical structure, C11H14O, CAS 144657-34-1
8-Methyl-4,4a,5,6-tetrahydronaphthalen-2(3H)-one
CAS 144657-34-1C11H14O
Dehydronootkatone chemical structure, C15H20O, CAS 5090-63-1
Dehydronootkatone
CAS 5090-63-1C15H20O
(3R,5R)-3,5-Dihydroxy-7-((1S,2S,8S,8aR)-2-methyl-8-(((S)-2-methylbutanoyl)oxy)-6-oxo-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid chemical structure, C23H34O7, CAS 201423-59-8
(3R,5R)-3,5-Dihydroxy-7-((1S,2S,8S,8aR)-2-methyl-8-(((S)-2-methylbutanoyl)oxy)-6-oxo-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid
CAS 201423-59-8C23H34O7
Chaetopenoid A chemical structure, C24H30O6, CAS 1893385-99-3
Chaetopenoid A
CAS 1893385-99-3C24H30O6
Chaetopenoid B chemical structure, C25H32O6, CAS 1893386-00-9
Chaetopenoid B
CAS 1893386-00-9C25H32O6