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Murcko scaffold

4,5,6,7-Tetrahydro-1-benzofuran-4-one scaffold

95 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
95
With full pages
17
Scaffold SMILES

O=C1CCCc2occc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4,5,6,7-Tetrahydro-1-benzofuran-4-one page
Murcko scaffold O=C1CCCc2occc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 95 of 95 chemicals

Methyl 2-methyl-4-oxo-4,5,6,7-tetrahydrobenzofuran-3-carboxylate chemical structure, C11H12O4, CAS 91143-41-8
Methyl 2-methyl-4-oxo-4,5,6,7-tetrahydrobenzofuran-3-carboxylate
CAS 91143-41-8C11H12O4
6,6-Dimethyl-4-oxo-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid chemical structure, C11H12O4, CAS 1023814-63-2
6,6-Dimethyl-4-oxo-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid
CAS 1023814-63-2C11H12O4
3-Benzofurancarboxylic acid, 4,5,6,7-tetrahydro-2,6-dimethyl-4-oxo- chemical structure, C11H12O4, CAS 1114596-50-7
3-Benzofurancarboxylic acid, 4,5,6,7-tetrahydro-2,6-dimethyl-4-oxo-
CAS 1114596-50-7C11H12O4
5-((Dimethylamino)methyl)-2-methyl-6,7-dihydrobenzofuran-4(5H)-one chemical structure, C12H17NO2, CAS 802594-95-2
5-((Dimethylamino)methyl)-2-methyl-6,7-dihydrobenzofuran-4(5H)-one
CAS 802594-95-2C12H17NO2
3-Methyl-4-oxo-N-(2,2,2-trifluoroethyl)-4,5,6,7-tetrahydrobenzofuran-2-carboxamide chemical structure, C12H12F3NO3, CAS 1355174-25-2
3-Methyl-4-oxo-N-(2,2,2-trifluoroethyl)-4,5,6,7-tetrahydrobenzofuran-2-carboxamide
CAS 1355174-25-2C12H12F3NO3
5,5-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran-4-one chemical structure, C10H12O2, CAS 881190-07-4
5,5-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran-4-one
CAS 881190-07-4C10H12O2
3,6-Dimethyl-4-oxo-4,5,6,7-tetrahydro-1-benzofuran-6-carbaldehyde chemical structure, C11H12O3, CAS 73702-87-1
3,6-Dimethyl-4-oxo-4,5,6,7-tetrahydro-1-benzofuran-6-carbaldehyde
CAS 73702-87-1C11H12O3
2-Methyl-6,7-dihydro-1-benzofuran-4(5H)-one dihydrate chemical structure, C9H14O4, CAS 1390654-40-6
2-Methyl-6,7-dihydro-1-benzofuran-4(5H)-one dihydrate
CAS 1390654-40-6C9H14O4
5-(2-Methoxyacetyl)-4,5,6,7-tetrahydro-1-benzofuran-4-one chemical structure, C11H12O4, CAS 1553975-79-3
5-(2-Methoxyacetyl)-4,5,6,7-tetrahydro-1-benzofuran-4-one
CAS 1553975-79-3C11H12O4
2-Bromo-6,7-dihydrobenzofuran-4(5H)-one chemical structure, C8H7BrO2, CAS 1781780-42-4
2-Bromo-6,7-dihydrobenzofuran-4(5H)-one
CAS 1781780-42-4C8H7BrO2
Ethyl 7,7-dimethyl-4-oxo-4,5,6,7-tetrahydrobenzofuran-3-carboxylate chemical structure, C13H16O4, CAS 1802180-33-1
Ethyl 7,7-dimethyl-4-oxo-4,5,6,7-tetrahydrobenzofuran-3-carboxylate
CAS 1802180-33-1C13H16O4
3-Methyl-4-oxo-6-(trifluoromethyl)-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid chemical structure, C11H9F3O4, CAS 1420794-93-9
3-Methyl-4-oxo-6-(trifluoromethyl)-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid
CAS 1420794-93-9C11H9F3O4
3-Methyl-6-(trifluoromethyl)-6,7-dihydrobenzofuran-4(5H)-one chemical structure, C10H9F3O2, CAS 1420793-41-4
3-Methyl-6-(trifluoromethyl)-6,7-dihydrobenzofuran-4(5H)-one
CAS 1420793-41-4C10H9F3O2
2-Methyl-6-(trifluoromethyl)-6,7-dihydrobenzofuran-4(5H)-one chemical structure, C10H9F3O2, CAS 1420791-34-9
2-Methyl-6-(trifluoromethyl)-6,7-dihydrobenzofuran-4(5H)-one
CAS 1420791-34-9C10H9F3O2
4-Oxo-6-(trifluoromethyl)-4,5,6,7-tetrahydrobenzofuran-3-carboxylic acid chemical structure, C10H7F3O4, CAS 1420795-08-9
4-Oxo-6-(trifluoromethyl)-4,5,6,7-tetrahydrobenzofuran-3-carboxylic acid
CAS 1420795-08-9C10H7F3O4
Ethyl 4-oxo-6-(trifluoromethyl)-4,5,6,7-tetrahydrobenzofuran-3-carboxylate chemical structure, C12H11F3O4, CAS 1420799-97-8
Ethyl 4-oxo-6-(trifluoromethyl)-4,5,6,7-tetrahydrobenzofuran-3-carboxylate
CAS 1420799-97-8C12H11F3O4
6-(Difluoromethyl)-3-methyl-6,7-dihydrobenzofuran-4(5H)-one chemical structure, C10H10F2O2, CAS 1706460-00-5
6-(Difluoromethyl)-3-methyl-6,7-dihydrobenzofuran-4(5H)-one
CAS 1706460-00-5C10H10F2O2
6-(Difluoromethyl)-2-methyl-6,7-dihydrobenzofuran-4(5H)-one chemical structure, C10H10F2O2, CAS 1706444-74-7
6-(Difluoromethyl)-2-methyl-6,7-dihydrobenzofuran-4(5H)-one
CAS 1706444-74-7C10H10F2O2
Ethyl 6-(difluoromethyl)-4-oxo-4,5,6,7-tetrahydrobenzofuran-3-carboxylate chemical structure, C12H12F2O4, CAS 1706458-67-4
Ethyl 6-(difluoromethyl)-4-oxo-4,5,6,7-tetrahydrobenzofuran-3-carboxylate
CAS 1706458-67-4C12H12F2O4
5-Butanoyl-4,5,6,7-tetrahydro-1-benzofuran-4-one chemical structure, C12H14O3, CAS 1550551-18-2
5-Butanoyl-4,5,6,7-tetrahydro-1-benzofuran-4-one
CAS 1550551-18-2C12H14O3
5-(2-Methylpropanoyl)-4,5,6,7-tetrahydro-1-benzofuran-4-one chemical structure, C12H14O3, CAS 1546811-85-1
5-(2-Methylpropanoyl)-4,5,6,7-tetrahydro-1-benzofuran-4-one
CAS 1546811-85-1C12H14O3
5-Propanoyl-4,5,6,7-tetrahydro-1-benzofuran-4-one chemical structure, C11H12O3, CAS 1553558-58-9
5-Propanoyl-4,5,6,7-tetrahydro-1-benzofuran-4-one
CAS 1553558-58-9C11H12O3
5-(2,2-Difluoroacetyl)-4,5,6,7-tetrahydro-1-benzofuran-4-one chemical structure, C10H8F2O3, CAS 1550544-21-2
5-(2,2-Difluoroacetyl)-4,5,6,7-tetrahydro-1-benzofuran-4-one
CAS 1550544-21-2C10H8F2O3
5-(Dimethoxymethyl)-4,5,6,7-tetrahydro-1-benzofuran-4-one chemical structure, C11H14O4, CAS 1550261-14-7
5-(Dimethoxymethyl)-4,5,6,7-tetrahydro-1-benzofuran-4-one
CAS 1550261-14-7C11H14O4