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Murcko scaffold

2-(Pyridin-3-yl)pyrimidine scaffold

132 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
132
With full pages
11
Scaffold SMILES

c1cnc(-c2cccnc2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyridin-3-yl)pyrimidine page
Murcko scaffold c1cnc(-c2cccnc2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 132 chemicals

6-Amino-5-nitroso-2-pyridin-3-ylpyrimidin-4-ylamine chemical structure, C9H8N6O, CAS 108106-16-7
6-Amino-5-nitroso-2-pyridin-3-ylpyrimidin-4-ylamine
CAS 108106-16-7C9H8N6O
4-Chloro-6-(methoxymethyl)-2-(pyridin-3-yl)pyrimidine chemical structure, C11H10ClN3O, CAS 339279-00-4
4-Chloro-6-(methoxymethyl)-2-(pyridin-3-yl)pyrimidine
CAS 339279-00-4C11H10ClN3O
4-(Dimethoxymethyl)-2-pyridin-3-ylpyrimidine chemical structure, C12H13N3O2, CAS 478046-42-3
4-(Dimethoxymethyl)-2-pyridin-3-ylpyrimidine
CAS 478046-42-3C12H13N3O2
4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine chemical structure, C10H5ClF3N3, CAS 204394-69-4
4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine
CAS 204394-69-4C10H5ClF3N3
5-(Methylsulfonyl)-2-(3-pyridinyl)-4-pyrimidinamine chemical structure, C10H10N4O2S, CAS 339108-21-3
5-(Methylsulfonyl)-2-(3-pyridinyl)-4-pyrimidinamine
CAS 339108-21-3C10H10N4O2S
N-[2-(3-Pyridinyl)-4-pyrimidinyl]acetamide chemical structure, C11H10N4O, CAS 866143-31-9
N-[2-(3-Pyridinyl)-4-pyrimidinyl]acetamide
CAS 866143-31-9C11H10N4O
2-Methyl-N-[2-(3-pyridinyl)-4-pyrimidinyl]propanamide chemical structure, C13H14N4O, CAS 866143-36-4
2-Methyl-N-[2-(3-pyridinyl)-4-pyrimidinyl]propanamide
CAS 866143-36-4C13H14N4O
N-[2-(3-Pyridinyl)-4-pyrimidinyl]propanamide chemical structure, C12H12N4O, CAS 866143-42-2
N-[2-(3-Pyridinyl)-4-pyrimidinyl]propanamide
CAS 866143-42-2C12H12N4O
2,2-Dimethyl-N-[2-(3-pyridinyl)-4-pyrimidinyl]propanamide chemical structure, C14H16N4O, CAS 866143-43-3
2,2-Dimethyl-N-[2-(3-pyridinyl)-4-pyrimidinyl]propanamide
CAS 866143-43-3C14H16N4O
4,5-Dichloro-6-methyl-2-(3-pyridyl)pyrimidine chemical structure, C10H7Cl2N3, CAS 681260-51-5
4,5-Dichloro-6-methyl-2-(3-pyridyl)pyrimidine
CAS 681260-51-5C10H7Cl2N3
2-(Pyridin-3-yl)pyrimidin-4-amine chemical structure, C9H8N4, CAS 61310-31-4
2-(Pyridin-3-yl)pyrimidin-4-amine
CAS 61310-31-4C9H8N4
5-(Isopropylsulfonyl)-2-(3-pyridyl)pyrimidin-4-amine chemical structure, C12H14N4O2S, CAS 175202-06-9
5-(Isopropylsulfonyl)-2-(3-pyridyl)pyrimidin-4-amine
CAS 175202-06-9C12H14N4O2S
4-Amino-2-(3-pyridyl)pyrimidine-5-carbonitrile chemical structure, C10H7N5, CAS 175205-75-1
4-Amino-2-(3-pyridyl)pyrimidine-5-carbonitrile
CAS 175205-75-1C10H7N5
N-[2-(3-Pyridinyl)-4-pyrimidinyl]pentanamide chemical structure, C14H16N4O, CAS 866143-37-5
N-[2-(3-Pyridinyl)-4-pyrimidinyl]pentanamide
CAS 866143-37-5C14H16N4O
4-(Methylsulfanyl)-6-((methylsulfanyl)methyl)-2-(3-pyridinyl)pyrimidine chemical structure, C12H13N3S2, CAS 478031-53-7
4-(Methylsulfanyl)-6-((methylsulfanyl)methyl)-2-(3-pyridinyl)pyrimidine
CAS 478031-53-7C12H13N3S2
(6-Chloro-2-(3-pyridinyl)-4-pyrimidinyl)methyl methyl sulfoxide chemical structure, C11H10ClN3OS, CAS 477711-31-2
(6-Chloro-2-(3-pyridinyl)-4-pyrimidinyl)methyl methyl sulfoxide
CAS 477711-31-2C11H10ClN3OS
N-Methyl-5-nitro-2-(3-pyridinyl)-4-pyrimidinamine chemical structure, C10H9N5O2, CAS 338417-25-7
N-Methyl-5-nitro-2-(3-pyridinyl)-4-pyrimidinamine
CAS 338417-25-7C10H9N5O2
2-(6-Methoxypyridin-3-yl)pyrimidine chemical structure, C10H9N3O, CAS 475275-81-1
2-(6-Methoxypyridin-3-yl)pyrimidine
CAS 475275-81-1C10H9N3O
N-Ethyl-N'-[2-(pyridin-3-yl)pyrimidin-4-yl]urea chemical structure, C12H13N5O, CAS 61310-19-8
N-Ethyl-N'-[2-(pyridin-3-yl)pyrimidin-4-yl]urea
CAS 61310-19-8C12H13N5O
N-Propan-2-yl-N'-[2-(pyridin-3-yl)pyrimidin-4-yl]urea chemical structure, C13H15N5O, CAS 61310-18-7
N-Propan-2-yl-N'-[2-(pyridin-3-yl)pyrimidin-4-yl]urea
CAS 61310-18-7C13H15N5O
N-Butyl-N'-[2-(pyridin-3-yl)pyrimidin-4-yl]urea chemical structure, C14H17N5O, CAS 61310-16-5
N-Butyl-N'-[2-(pyridin-3-yl)pyrimidin-4-yl]urea
CAS 61310-16-5C14H17N5O
N-tert-Butyl-N'-[2-(pyridin-3-yl)pyrimidin-4-yl]urea chemical structure, C14H17N5O, CAS 61310-17-6
N-tert-Butyl-N'-[2-(pyridin-3-yl)pyrimidin-4-yl]urea
CAS 61310-17-6C14H17N5O
2-(Pyridin-3-yl)pyrimidine chemical structure, C9H7N3, CAS 73082-74-3
2-(Pyridin-3-yl)pyrimidine
CAS 73082-74-3C9H7N3
4-Chloro-2-(pyridin-3-yl)pyrimidine chemical structure, C9H6ClN3, CAS 97603-39-9
4-Chloro-2-(pyridin-3-yl)pyrimidine
CAS 97603-39-9C9H6ClN3