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Murcko scaffold

7-Deazahypoxanthine scaffold

123 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
123
With full pages
18
Scaffold SMILES

O=c1[nH]cnc2[nH]ccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 7-Deazahypoxanthine page
Murcko scaffold O=c1[nH]cnc2[nH]ccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 123 chemicals

1-Methyl-2-(methylsulfanyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C8H9N3OS, CAS 29877-81-4
1-Methyl-2-(methylsulfanyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 29877-81-4C8H9N3OS
3-Methyl-2-(methylsulfanyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C8H9N3OS, CAS 29877-79-0
3-Methyl-2-(methylsulfanyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 29877-79-0C8H9N3OS
2-Amino-3-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C7H8N4O, CAS 90065-67-1
2-Amino-3-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one
CAS 90065-67-1C7H8N4O
3-Methyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C7H7N3O, CAS 81965-15-3
3-Methyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 81965-15-3C7H7N3O
2-Amino-1-methyl-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C7H8N4O, CAS 90065-75-1
2-Amino-1-methyl-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 90065-75-1C7H8N4O
7-Methoxy-3-methyl-2-[(methylsulfanyl)amino]-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C9H12N4O2S, CAS 90065-68-2
7-Methoxy-3-methyl-2-[(methylsulfanyl)amino]-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 90065-68-2C9H12N4O2S
2-Amino-1-methyl-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one--hydrogen chloride (1/1) chemical structure, C7H9ClN4O, CAS 90065-70-6
2-Amino-1-methyl-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one--hydrogen chloride (1/1)
CAS 90065-70-6C7H9ClN4O
N-(7-(Methoxymethyl)-3-methyl-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-2-yl)acetamide chemical structure, C11H14N4O3, CAS 90065-69-3
N-(7-(Methoxymethyl)-3-methyl-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-2-yl)acetamide
CAS 90065-69-3C11H14N4O3
5-Iodo-3-methyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one chemical structure, C7H6IN3O, CAS 1410974-90-1
5-Iodo-3-methyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
CAS 1410974-90-1C7H6IN3O
7-Aminomethyl-7-carbaguanine chemical structure, C7H9N5O, CAS 69251-45-2
7-Aminomethyl-7-carbaguanine
CAS 69251-45-2C7H9N5O
5-((Dimethylamino)methyl)-7H-pyrrolo(2,3-d)pyrimidin-4-ol chemical structure, C9H12N4O, CAS 1618-45-7
5-((Dimethylamino)methyl)-7H-pyrrolo(2,3-d)pyrimidin-4-ol
CAS 1618-45-7C9H12N4O
7-Deazahypoxanthine chemical structure, C6H5N3O, CAS 3680-71-5
7-Deazahypoxanthine
CAS 3680-71-5C6H5N3O
7-Deazaguanine chemical structure, C6H6N4O, CAS 7355-55-7
7-Deazaguanine
CAS 7355-55-7C6H6N4O
2-Amino-5-iodo-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one chemical structure, C6H5IN4O, CAS 163622-51-3
2-Amino-5-iodo-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
CAS 163622-51-3C6H5IN4O
2-Amino-7-methyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one chemical structure, C7H8N4O, CAS 90065-66-0
2-Amino-7-methyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
CAS 90065-66-0C7H8N4O
2-Amino-7-(2-hydroxyethoxymethyl)-3H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C9H12N4O3, CAS 84955-38-4
2-Amino-7-(2-hydroxyethoxymethyl)-3H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 84955-38-4C9H12N4O3
5-Iodo-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one chemical structure, C6H4IN3O, CAS 135352-71-5
5-Iodo-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one
CAS 135352-71-5C6H4IN3O
1H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 2-amino-7-(2,3-dihydroxypropyl)-4,7-dihydro-4-oxo- chemical structure, C10H11N5O3, CAS 127945-77-1
1H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 2-amino-7-(2,3-dihydroxypropyl)-4,7-dihydro-4-oxo-
CAS 127945-77-1C10H11N5O3
7-Cyano-7-deazaguanine chemical structure, C7H5N5O, CAS 69205-79-4
7-Cyano-7-deazaguanine
CAS 69205-79-4C7H5N5O
5-Iodo-2-methyl-3,7-dihydro-pyrrolo[2,3-D]pyrimidin-4-one chemical structure, C7H6IN3O, CAS 135352-75-9
5-Iodo-2-methyl-3,7-dihydro-pyrrolo[2,3-D]pyrimidin-4-one
CAS 135352-75-9C7H6IN3O
4H-Pyrrolo[2,3-d]pyrimidin-4-one, 1,7-dihydro-2,5-dimethyl- chemical structure, C8H9N3O, CAS 95927-51-8
4H-Pyrrolo[2,3-d]pyrimidin-4-one, 1,7-dihydro-2,5-dimethyl-
CAS 95927-51-8C8H9N3O
2-Amino-7-propyl-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C9H12N4O, CAS 93263-27-5
2-Amino-7-propyl-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 93263-27-5C9H12N4O
(4-Bromophenyl)(5,7,7-trimethyl-7H-imidazo[2,1-b][1,3]thiazin-3-yl)methanone chemical structure, C9H13N5O, CAS 62981-83-3
(4-Bromophenyl)(5,7,7-trimethyl-7H-imidazo[2,1-b][1,3]thiazin-3-yl)methanone
CAS 62981-83-3C9H13N5O
Methyl 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboxylate chemical structure, C8H8N4O3, CAS 124738-76-7
Methyl 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboxylate
CAS 124738-76-7C8H8N4O3