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Murcko scaffold

1-(Thiophene-2-sulfonyl)-1,4-diazepane scaffold

7 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
7
With full pages
1
Scaffold SMILES

O=S(=O)(c1cccs1)N1CCCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Thiophene-2-sulfonyl)-1,4-diazepane page
Murcko scaffold O=S(=O)(c1cccs1)N1CCCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

1-[(5-Bromothiophen-2-yl)sulfonyl]-1,4-diazepane chemical structure, C9H13BrN2O2S2, CAS 924873-36-9
1-[(5-Bromothiophen-2-yl)sulfonyl]-1,4-diazepane
CAS 924873-36-9C9H13BrN2O2S2
1-(Thiophene-2-sulfonyl)-1,4-diazepane chemical structure, C9H14N2O2S2, CAS 926235-22-5
1-(Thiophene-2-sulfonyl)-1,4-diazepane
CAS 926235-22-5C9H14N2O2S2
1-[(5-Chlorothiophen-2-yl)sulfonyl]-1,4-diazepane chemical structure, C9H13ClN2O2S2, CAS 1082556-62-4
1-[(5-Chlorothiophen-2-yl)sulfonyl]-1,4-diazepane
CAS 1082556-62-4C9H13ClN2O2S2
1-[(5-Bromothiophen-2-yl)sulfonyl]-1,4-diazepane hydrochloride chemical structure, C9H14BrClN2O2S2, CAS 1365836-42-5
1-[(5-Bromothiophen-2-yl)sulfonyl]-1,4-diazepane hydrochloride
CAS 1365836-42-5C9H14BrClN2O2S2
1-(Thiophen-2-ylsulfonyl)-1,4-diazepane hydrochloride chemical structure, C9H15ClN2O2S2, CAS 1420995-70-5
1-(Thiophen-2-ylsulfonyl)-1,4-diazepane hydrochloride
CAS 1420995-70-5C9H15ClN2O2S2
N-(2-{4-[(5-Chlorothiophen-2-yl)sulfonyl]-1,4-diazepan-1-yl}-2-oxoethyl)-N-ethylprop-2-enamide chemical structure, C16H22ClN3O4S2, CAS 2361745-00-6
N-(2-{4-[(5-Chlorothiophen-2-yl)sulfonyl]-1,4-diazepan-1-yl}-2-oxoethyl)-N-ethylprop-2-enamide
CAS 2361745-00-6C16H22ClN3O4S2
tert-Butyl 4-[(5-bromothiophen-2-yl)sulfonyl]-1,4-diazepane-1-carboxylate chemical structure, C14H21BrN2O4S2, CAS 2326075-71-0
tert-Butyl 4-[(5-bromothiophen-2-yl)sulfonyl]-1,4-diazepane-1-carboxylate
CAS 2326075-71-0C14H21BrN2O4S2