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Murcko scaffold

Ring system with 3 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
10
With full pages
7
Scaffold SMILES

O=C1CC(C(=O)Nc2ccccc2)C2(CCOCC2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(C(=O)Nc2ccccc2)C2(CCOCC2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

7,7-Dimethyl-N-(2-methylphenyl)-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide chemical structure, C18H23NO4, CAS 671765-71-2
7,7-Dimethyl-N-(2-methylphenyl)-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide
CAS 671765-71-2C18H23NO4
N-Ethyl-7,7-dimethyl-2-oxo-N-phenyl-1,8-dioxaspiro[4.5]decane-4-carboxamide chemical structure, C19H25NO4, CAS 633284-15-8
N-Ethyl-7,7-dimethyl-2-oxo-N-phenyl-1,8-dioxaspiro[4.5]decane-4-carboxamide
CAS 633284-15-8C19H25NO4
7,7-Dimethyl-N-(4-nitrophenyl)-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide chemical structure, C17H20N2O6, CAS 690691-82-8
7,7-Dimethyl-N-(4-nitrophenyl)-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide
CAS 690691-82-8C17H20N2O6
N-(3-Methoxyphenyl)-7,7-dimethyl-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide chemical structure, C18H23NO5, CAS 672274-59-8
N-(3-Methoxyphenyl)-7,7-dimethyl-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide
CAS 672274-59-8C18H23NO5
7,7-Dimethyl-N-(4-methylphenyl)-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide chemical structure, C18H23NO4, CAS 654635-30-0
7,7-Dimethyl-N-(4-methylphenyl)-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide
CAS 654635-30-0C18H23NO4
7,7-Dimethyl-N-(2-methyl-5-nitrophenyl)-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide chemical structure, C18H22N2O6, CAS 690695-31-9
7,7-Dimethyl-N-(2-methyl-5-nitrophenyl)-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide
CAS 690695-31-9C18H22N2O6
N-(4-Methoxyphenyl)-7,7-dimethyl-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide chemical structure, C18H23NO5, CAS 633284-11-4
N-(4-Methoxyphenyl)-7,7-dimethyl-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide
CAS 633284-11-4C18H23NO5
N-(4-Bromophenyl)-7,7-dimethyl-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide chemical structure, C17H20BrNO4, CAS 654635-32-2
N-(4-Bromophenyl)-7,7-dimethyl-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide
CAS 654635-32-2C17H20BrNO4
N-(2-Chlorophenyl)-7,7-dimethyl-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide chemical structure, C17H20ClNO4, CAS 693255-12-8
N-(2-Chlorophenyl)-7,7-dimethyl-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide
CAS 693255-12-8C17H20ClNO4
N-(2,6-Dichlorophenyl)-7,7-dimethyl-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide chemical structure, C17H19Cl2NO4, CAS 633284-14-7
N-(2,6-Dichlorophenyl)-7,7-dimethyl-2-oxo-1,8-dioxaspiro[4.5]decane-4-carboxamide
CAS 633284-14-7C17H19Cl2NO4