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Murcko scaffold

Ring system with 4 rings and 24 atoms

15 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
15
With full pages
1
Scaffold SMILES

C(=NOCc1ccccc1)c1c(-c2ccccc2)nc2sccn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=NOCc1ccccc1)c1c(-c2ccccc2)nc2sccn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

6-(4-Chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime chemical structure, C19H12Cl3N3OS, CAS 338404-52-7
6-(4-Chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime
CAS 338404-52-7C19H12Cl3N3OS
6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(4-nitrobenzyl)oxime chemical structure, C19H13ClN4O3S, CAS 338404-56-1
6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(4-nitrobenzyl)oxime
CAS 338404-56-1C19H13ClN4O3S
6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-benzyloxime chemical structure, C19H14BrN3OS, CAS 685106-62-1
6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-benzyloxime
CAS 685106-62-1C19H14BrN3OS
6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl)oxime chemical structure, C19H12Cl3N3OS, CAS 338404-54-9
6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl)oxime
CAS 338404-54-9C19H12Cl3N3OS
6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2,4-dichlorobenzyl)oxime chemical structure, C19H12Cl3N3OS, CAS 338404-55-0
6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2,4-dichlorobenzyl)oxime
CAS 338404-55-0C19H12Cl3N3OS
6-(4-Methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2,4-dichlorobenzyl)oxime chemical structure, C20H15Cl2N3OS, CAS 691883-94-0
6-(4-Methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2,4-dichlorobenzyl)oxime
CAS 691883-94-0C20H15Cl2N3OS
6-Phenylimidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime chemical structure, C19H13Cl2N3OS, CAS 400078-51-5
6-Phenylimidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime
CAS 400078-51-5C19H13Cl2N3OS
6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2-chloro-6-fluorobenzyl)oxime chemical structure, C19H12BrClFN3OS, CAS 691883-98-4
6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2-chloro-6-fluorobenzyl)oxime
CAS 691883-98-4C19H12BrClFN3OS
6-(4-Methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-[4-(tert-butyl)benzyl]oxime chemical structure, C24H25N3OS, CAS 865657-65-4
6-(4-Methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-[4-(tert-butyl)benzyl]oxime
CAS 865657-65-4C24H25N3OS
6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-[4-(trifluoromethyl)benzyl]oxime chemical structure, C20H13BrF3N3OS, CAS 691884-00-1
6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-[4-(trifluoromethyl)benzyl]oxime
CAS 691884-00-1C20H13BrF3N3OS
6-(4-Methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2-chloro-6-fluorobenzyl)oxime chemical structure, C20H15ClFN3OS, CAS 691883-95-1
6-(4-Methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2-chloro-6-fluorobenzyl)oxime
CAS 691883-95-1C20H15ClFN3OS
6-Phenylimidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl)oxime chemical structure, C19H13Cl2N3OS, CAS 337475-27-1
6-Phenylimidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl)oxime
CAS 337475-27-1C19H13Cl2N3OS
6-Phenylimidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(4-nitrobenzyl)oxime chemical structure, C19H14N4O3S, CAS 330969-92-1
6-Phenylimidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(4-nitrobenzyl)oxime
CAS 330969-92-1C19H14N4O3S
6-Phenylimidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2,4-dichlorobenzyl)oxime chemical structure, C19H13Cl2N3OS, CAS 338395-43-0
6-Phenylimidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(2,4-dichlorobenzyl)oxime
CAS 338395-43-0C19H13Cl2N3OS
6-(4-Methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(4-chlorobenzyl)oxime chemical structure, C20H16ClN3OS, CAS 861212-98-8
6-(4-Methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(4-chlorobenzyl)oxime
CAS 861212-98-8C20H16ClN3OS