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Murcko scaffold

2-(1H-Pyrazol-1-yl)quinoline scaffold

34 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
34
With full pages
5
Scaffold SMILES

c1ccc2nc(-n3cccn3)ccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Pyrazol-1-yl)quinoline page
Murcko scaffold c1ccc2nc(-n3cccn3)ccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

2-(3,5-Dimethyl-1H-pyrazol-1-yl)-4-methylquinoline chemical structure, C15H15N3, CAS 71508-97-9
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-4-methylquinoline
CAS 71508-97-9C15H15N3
5-Amino-1-(4-methylquinolin-2-yl)-1H-pyrazole-4-carboxamide chemical structure, C14H13N5O, CAS 379242-98-5
5-Amino-1-(4-methylquinolin-2-yl)-1H-pyrazole-4-carboxamide
CAS 379242-98-5C14H13N5O
RefChem:345353 chemical structure, C14H14N4, CAS 307342-03-6
RefChem:345353
CAS 307342-03-6C14H14N4
Ethyl 5-amino-1-(4-methylquinolin-2-yl)-1H-pyrazole-4-carboxylate chemical structure, C16H16N4O2, CAS 301223-05-2
Ethyl 5-amino-1-(4-methylquinolin-2-yl)-1H-pyrazole-4-carboxylate
CAS 301223-05-2C16H16N4O2
2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinolin-8-ol chemical structure, C14H13N3O, CAS 18239-59-3
2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinolin-8-ol
CAS 18239-59-3C14H13N3O
5,7-Dichloro-2-(3,5-dimethyl-1H-pyrazol-1-yl)quinolin-8-ol chemical structure, C14H11Cl2N3O, CAS 355014-38-9
5,7-Dichloro-2-(3,5-dimethyl-1H-pyrazol-1-yl)quinolin-8-ol
CAS 355014-38-9C14H11Cl2N3O
2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinolin-8-amine chemical structure, C14H14N4, CAS 356522-39-9
2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinolin-8-amine
CAS 356522-39-9C14H14N4
Quinoline, 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-4-methyl- chemical structure, C16H17N3O, CAS 71509-00-7
Quinoline, 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-4-methyl-
CAS 71509-00-7C16H17N3O
Quinoline, 6-chloro-2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-methyl- chemical structure, C15H14ClN3, CAS 108936-72-7
Quinoline, 6-chloro-2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-methyl-
CAS 108936-72-7C15H14ClN3
Quinoline, 2-(4-butyl-3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-4-methyl- chemical structure, C20H25N3O, CAS 108936-75-0
Quinoline, 2-(4-butyl-3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-4-methyl-
CAS 108936-75-0C20H25N3O
1H-Pyrazole-4-acetic acid, 3,5-dimethyl-1-(6-fluoro-4-methyl-2-quinolinyl)- chemical structure, C17H16FN3O2, CAS 109274-62-6
1H-Pyrazole-4-acetic acid, 3,5-dimethyl-1-(6-fluoro-4-methyl-2-quinolinyl)-
CAS 109274-62-6C17H16FN3O2
2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinoline chemical structure, C14H13N3, CAS 38696-04-7
2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinoline
CAS 38696-04-7C14H13N3
(E)-N'-(4-Cyano-1-(4-methylquinolin-2-yl)-1H-pyrazol-5-yl)-N,N-dimethylformimidamide chemical structure, C17H16N6, CAS 303788-42-3
(E)-N'-(4-Cyano-1-(4-methylquinolin-2-yl)-1H-pyrazol-5-yl)-N,N-dimethylformimidamide
CAS 303788-42-3C17H16N6
(E)-Ethyl 5-(((dimethylamino)methylene)amino)-1-(4-methylquinolin-2-yl)-1H-pyrazole-4-carboxylate chemical structure, C19H21N5O2, CAS 1001873-44-4
(E)-Ethyl 5-(((dimethylamino)methylene)amino)-1-(4-methylquinolin-2-yl)-1H-pyrazole-4-carboxylate
CAS 1001873-44-4C19H21N5O2
Ethyl 5-amino-1-(quinolin-2-yl)-1H-pyrazole-4-carboxylate chemical structure, C15H14N4O2, CAS 111857-58-0
Ethyl 5-amino-1-(quinolin-2-yl)-1H-pyrazole-4-carboxylate
CAS 111857-58-0C15H14N4O2
2-(1H-Pyrazol-1-yl)quinoline chemical structure, C12H9N3, CAS 123464-68-6
2-(1H-Pyrazol-1-yl)quinoline
CAS 123464-68-6C12H9N3
Ethyl 5-chloro-1-(2-quinolinyl)-1H-pyrazole-4-carboxylate chemical structure, C15H12ClN3O2, CAS 111857-59-1
Ethyl 5-chloro-1-(2-quinolinyl)-1H-pyrazole-4-carboxylate
CAS 111857-59-1C15H12ClN3O2
2-(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)-3-methylquinoline-4-carboxylic acid chemical structure, C16H14ClN3O2, CAS 1006458-53-2
2-(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)-3-methylquinoline-4-carboxylic acid
CAS 1006458-53-2C16H14ClN3O2
3-Methyl-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]quinoline-4-carboxylic acid chemical structure, C16H12F3N3O2, CAS 1006458-57-6
3-Methyl-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]quinoline-4-carboxylic acid
CAS 1006458-57-6C16H12F3N3O2
5-Amino-1-quinolin-2-yl-1H-pyrazole-4-carbonitrile chemical structure, C13H9N5, CAS 1017665-69-8
5-Amino-1-quinolin-2-yl-1H-pyrazole-4-carbonitrile
CAS 1017665-69-8C13H9N5
5-Ethyl-1-(2-quinolinyl)-1H-pyrazole-4-carboxylic acid chemical structure, C15H13N3O2, CAS 241800-83-9
5-Ethyl-1-(2-quinolinyl)-1H-pyrazole-4-carboxylic acid
CAS 241800-83-9C15H13N3O2
Ethyl 5-[(dimethylcarbamoyl)amino]-1-(quinolin-2-yl)-1H-pyrazole-4-carboxylate chemical structure, C18H19N5O3, CAS 1177821-95-2
Ethyl 5-[(dimethylcarbamoyl)amino]-1-(quinolin-2-yl)-1H-pyrazole-4-carboxylate
CAS 1177821-95-2C18H19N5O3
2-(1H-Pyrazol-1-yl)quinoline-4-carboxylic acid chemical structure, C13H9N3O2, CAS 1152718-85-8
2-(1H-Pyrazol-1-yl)quinoline-4-carboxylic acid
CAS 1152718-85-8C13H9N3O2
2-(5-Amino-3-methyl-1H-pyrazol-1-yl)-6,7-dichloroquinolin-8-ol chemical structure, C13H10Cl2N4O, CAS 1170301-32-2
2-(5-Amino-3-methyl-1H-pyrazol-1-yl)-6,7-dichloroquinolin-8-ol
CAS 1170301-32-2C13H10Cl2N4O