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Murcko scaffold

Ring system with 3 rings and 15 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
20
With full pages
10
Scaffold SMILES

c1nc(-c2ccc3c(c2)OCCO3)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(-c2ccc3c(c2)OCCO3)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

N-(4-(1,4-Benzodioxan-6-yl)-2-thiazolyl)oxamic acid chemical structure, C15H17N3O6S, CAS 74604-77-6
N-(4-(1,4-Benzodioxan-6-yl)-2-thiazolyl)oxamic acid
CAS 74604-77-6C15H17N3O6S
Enoxamast chemical structure, C13H10N2O5S, CAS 74604-76-5
Enoxamast
CAS 74604-76-5C13H10N2O5S
4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine chemical structure, C11H10N2O2S, CAS 105362-06-9
4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine
CAS 105362-06-9C11H10N2O2S
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]-2-methylsulfanylacetamide chemical structure, C14H14N2O3S2, CAS 795282-70-1
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]-2-methylsulfanylacetamide
CAS 795282-70-1C14H14N2O3S2
4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-methyl-1,3-thiazole chemical structure, C12H11NO2S, CAS 791601-24-6
4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-methyl-1,3-thiazole
CAS 791601-24-6C12H11NO2S
2-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]acetonitrile chemical structure, C13H10N2O2S, CAS 499771-17-4
2-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]acetonitrile
CAS 499771-17-4C13H10N2O2S
4-(7-Chloro-2,3-dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine chemical structure, C11H9ClN2O2S, CAS 915873-63-1
4-(7-Chloro-2,3-dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine
CAS 915873-63-1C11H9ClN2O2S
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]acetamide chemical structure, C13H12N2O3S, CAS 864860-91-3
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]acetamide
CAS 864860-91-3C13H12N2O3S
4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazole-2-carbaldehyde chemical structure, C12H9NO3S, CAS 383144-16-9
4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazole-2-carbaldehyde
CAS 383144-16-9C12H9NO3S
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]butanamide chemical structure, C15H16N2O3S, CAS 864937-42-8
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]butanamide
CAS 864937-42-8C15H16N2O3S
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]propanamide chemical structure, C14H14N2O3S, CAS 864937-39-3
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]propanamide
CAS 864937-39-3C14H14N2O3S
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]pentanamide chemical structure, C16H18N2O3S, CAS 888410-37-5
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]pentanamide
CAS 888410-37-5C16H18N2O3S
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]-2,2-dimethylpropanamide chemical structure, C16H18N2O3S, CAS 888410-39-7
N-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
CAS 888410-39-7C16H18N2O3S
4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-2-thiazolamine chemical structure, C12H12N2O2S, CAS 887031-20-1
4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-2-thiazolamine
CAS 887031-20-1C12H12N2O2S
2-Amino-4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-thiazoleacetic acid chemical structure, C13H12N2O4S, CAS 887031-24-5
2-Amino-4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-thiazoleacetic acid
CAS 887031-24-5C13H12N2O4S
4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-3H-thiazol-2-ylideneamine hydrochloride chemical structure, C11H11ClN2O2S, CAS 1052527-15-7
4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-3H-thiazol-2-ylideneamine hydrochloride
CAS 1052527-15-7C11H11ClN2O2S
4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N-prop-2-enyl-1,3-thiazol-2-amine chemical structure, C14H14N2O2S, CAS 1016475-92-5
4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N-prop-2-enyl-1,3-thiazol-2-amine
CAS 1016475-92-5C14H14N2O2S
1-(4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)thiazol-2-yl)-3-isopropylurea chemical structure, C15H17N3O3S, CAS 1206986-66-4
1-(4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)thiazol-2-yl)-3-isopropylurea
CAS 1206986-66-4C15H17N3O3S
Ethyl 4-(6-benzodioxane)thiazole-2-carboxylate chemical structure, C14H13NO4S, CAS 1159979-44-8
Ethyl 4-(6-benzodioxane)thiazole-2-carboxylate
CAS 1159979-44-8C14H13NO4S
2-Bromo-4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)thiazole chemical structure, C11H8BrNO2S, CAS 1225789-34-3
2-Bromo-4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)thiazole
CAS 1225789-34-3C11H8BrNO2S