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Murcko scaffold

Ring system with 3 rings and 16 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
7
With full pages
5
Scaffold SMILES

O=c1[nH]c(-n2cccn2)nc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c(-n2cccn2)nc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

2-(3,5-Dimethylpyrazol-1-yl)-3-(2-methylpropoxy)quinazolin-4-one chemical structure, C17H20N4O2, CAS 850764-15-7
2-(3,5-Dimethylpyrazol-1-yl)-3-(2-methylpropoxy)quinazolin-4-one
CAS 850764-15-7C17H20N4O2
Ethyl 2-[2-(3,5-dimethylpyrazol-1-yl)-4-oxoquinazolin-3-yl]oxypropanoate chemical structure, C18H20N4O4, CAS 850752-49-7
Ethyl 2-[2-(3,5-dimethylpyrazol-1-yl)-4-oxoquinazolin-3-yl]oxypropanoate
CAS 850752-49-7C18H20N4O4
Methyl 2-[2-(3,5-dimethylpyrazol-1-yl)-4-oxoquinazolin-3-yl]oxyacetate chemical structure, C16H16N4O4, CAS 958944-12-2
Methyl 2-[2-(3,5-dimethylpyrazol-1-yl)-4-oxoquinazolin-3-yl]oxyacetate
CAS 958944-12-2C16H16N4O4
Ethyl 2-[2-(3,5-dimethylpyrazol-1-yl)-4-oxoquinazolin-3-yl]oxyacetate chemical structure, C17H18N4O4, CAS 1004097-12-4
Ethyl 2-[2-(3,5-dimethylpyrazol-1-yl)-4-oxoquinazolin-3-yl]oxyacetate
CAS 1004097-12-4C17H18N4O4
2-(3,5-Dimethylpyrazol-1-yl)-3-prop-2-enoxyquinazolin-4-one chemical structure, C16H16N4O2, CAS 879457-82-6
2-(3,5-Dimethylpyrazol-1-yl)-3-prop-2-enoxyquinazolin-4-one
CAS 879457-82-6C16H16N4O2
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-3-methyl-3,4-dihydroquinazolin-4-one chemical structure, C14H14N4O, CAS 2310124-03-7
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-3-methyl-3,4-dihydroquinazolin-4-one
CAS 2310124-03-7C14H14N4O
5-Amino-1-(3,4-dihydro-4-oxo-2-quinazolinyl)-1H-pyrazole-4-carbonitrile chemical structure, C12H8N6O, CAS 1753-59-9
5-Amino-1-(3,4-dihydro-4-oxo-2-quinazolinyl)-1H-pyrazole-4-carbonitrile
CAS 1753-59-9C12H8N6O