Murcko scaffold
Ring system with 4 rings and 26 atoms
18 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 26
- Chemicals
- 18
- With full pages
- 1
Scaffold SMILES
O=C(CCc1cc2cc3ccoc3cc2oc1=O)NCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 18 of 18 chemicals
![N-(3,4-Dimethoxybenzyl)-3-(3,5-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C25H25NO6, CAS 858750-81-9](/s/KSGPKSKWCYQRGH-UHFFFAOYSA-N.svg)
N-(3,4-Dimethoxybenzyl)-3-(3,5-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858750-81-9C25H25NO6
![3-(3,5-Dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-N-(2-methoxybenzyl)propanamide chemical structure, C24H23NO5, CAS 858754-95-7](/s/YVTRVOCTBJHFFE-UHFFFAOYSA-N.svg)
3-(3,5-Dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-N-(2-methoxybenzyl)propanamide
CAS 858754-95-7C24H23NO5
![N-(4-Chlorobenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C24H22ClNO4, CAS 858751-05-0](/s/WPYNDZWRIVLOHY-UHFFFAOYSA-N.svg)
N-(4-Chlorobenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858751-05-0C24H22ClNO4
![N-Benzyl-3-(3,5-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C23H21NO4, CAS 858752-30-4](/s/ZIKRRFDJOQSTCF-UHFFFAOYSA-N.svg)
N-Benzyl-3-(3,5-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858752-30-4C23H21NO4
![N-(2-Methoxybenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C25H25NO5, CAS 858754-49-1](/s/ASQXLGGZULHKFN-UHFFFAOYSA-N.svg)
N-(2-Methoxybenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858754-49-1C25H25NO5
![N-(4-Chlorobenzyl)-3-(3,5-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C23H20ClNO4, CAS 858756-10-2](/s/OXHVPBVLAIKRGS-UHFFFAOYSA-N.svg)
N-(4-Chlorobenzyl)-3-(3,5-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858756-10-2C23H20ClNO4
![N-(4-Methoxybenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C25H25NO5, CAS 858756-50-0](/s/LGHBYYNKIPTFDM-UHFFFAOYSA-N.svg)
N-(4-Methoxybenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858756-50-0C25H25NO5
![N-(2-Chlorobenzyl)-3-(3,5-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C23H20ClNO4, CAS 858755-23-4](/s/XURFWWBVADUSQL-UHFFFAOYSA-N.svg)
N-(2-Chlorobenzyl)-3-(3,5-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858755-23-4C23H20ClNO4
![N-(3,4-Dimethoxybenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C26H27NO6, CAS 858758-51-7](/s/LHYKSGHJGVTJEA-UHFFFAOYSA-N.svg)
N-(3,4-Dimethoxybenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858758-51-7C26H27NO6
![N-(2-Chlorobenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C24H22ClNO4, CAS 858749-53-8](/s/QSQVCUTYMRAPRR-UHFFFAOYSA-N.svg)
N-(2-Chlorobenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858749-53-8C24H22ClNO4
![3-(3,5-Dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-N-(4-methoxybenzyl)propanamide chemical structure, C24H23NO5, CAS 858747-69-0](/s/RKFJDUQJADMUHH-UHFFFAOYSA-N.svg)
3-(3,5-Dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-N-(4-methoxybenzyl)propanamide
CAS 858747-69-0C24H23NO5
![N-(4-Fluorobenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C24H22FNO4, CAS 858748-13-7](/s/SDKSATPOIXBHOC-UHFFFAOYSA-N.svg)
N-(4-Fluorobenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858748-13-7C24H22FNO4
![N-(4-Methylbenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C25H25NO4, CAS 858749-39-0](/s/QPLDQQXEQYNQDG-UHFFFAOYSA-N.svg)
N-(4-Methylbenzyl)-3-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 858749-39-0C25H25NO4
![3-(3,5-Dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-N-(4-fluorobenzyl)propanamide chemical structure, C23H20FNO4, CAS 858753-78-3](/s/JDOLJPIZIFQAFD-UHFFFAOYSA-N.svg)
3-(3,5-Dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-N-(4-fluorobenzyl)propanamide
CAS 858753-78-3C23H20FNO4
![3-(3,5-Dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-N-(3-methoxybenzyl)propanamide chemical structure, C24H23NO5, CAS 853899-83-9](/s/AIICCICLSPRMNN-UHFFFAOYSA-N.svg)
3-(3,5-Dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-N-(3-methoxybenzyl)propanamide
CAS 853899-83-9C24H23NO5
![N-Benzyl-3-{2,3,5,9-tetramethyl-7-oxo-7H-furo[3,2-G]chromen-6-YL}propanamide chemical structure, C25H25NO4, CAS 853900-00-2](/s/FGJPRQBPPLNKHZ-UHFFFAOYSA-N.svg)
N-Benzyl-3-{2,3,5,9-tetramethyl-7-oxo-7H-furo[3,2-G]chromen-6-YL}propanamide
CAS 853900-00-2C25H25NO4
![N-(3,4-Dimethoxybenzyl)-3-(3,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide chemical structure, C26H27NO6, CAS 853900-11-5](/s/OVLVHLDYFARLRV-UHFFFAOYSA-N.svg)
N-(3,4-Dimethoxybenzyl)-3-(3,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanamide
CAS 853900-11-5C26H27NO6
![N-[(4-Methoxyphenyl)methyl]-3-(3,5,9-trimethyl-7-oxofuro[3,2-g]chromen-6-yl)propanamide chemical structure, C25H25NO5, CAS 853900-12-6](/s/IWDHMJJIVUUUOQ-UHFFFAOYSA-N.svg)
N-[(4-Methoxyphenyl)methyl]-3-(3,5,9-trimethyl-7-oxofuro[3,2-g]chromen-6-yl)propanamide
CAS 853900-12-6C25H25NO5
Related scaffolds
Same ring framework with different atoms or bond orders
