Murcko scaffold
Ring system with 5 rings and 18 atoms
28 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 18
- Chemicals
- 28
- With full pages
- 2
Scaffold SMILES
C1=CC2Oc3cccc4c3C23CCNC(C4)C3C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 28 of 28 chemicals
![(9-Methoxy-3,6-dimethyl-2,4,4a,5,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl) acetate chemical structure, C21H25NO4, CAS 7598-79-0](/s/YEHPWZSOFCYYES-UHFFFAOYSA-N.svg)
(9-Methoxy-3,6-dimethyl-2,4,4a,5,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl) acetate
CAS 7598-79-0C21H25NO4
delta-6 Codeine
CAS 6252-51-3C18H21NO3
Methyldesorphine
CAS 16008-36-9C18H21NO2
gamma-Isomorphine
CAS 466-93-3C17H19NO3
(5alpha,8alpha)-6,7-Didehydro-4,5-epoxy-17-methylmorphinan-3,8-diol
CAS 466-94-4C17H19NO3
beta-Chlorocodide
CAS 466-95-5C18H20ClNO2
Pseudocodeine
CAS 466-96-6C18H21NO3
Morphinan-8-ol, 6,7-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,8alpha)-
CAS 509-55-7C18H21NO3
Dihydrothebaine
CAS 561-25-1C19H23NO3
Morphinan, 6,7-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha)-
CAS 1034-48-6C18H21NO2
Pseudocodeine methyl ether
CAS 4912-71-4C19H23NO3
Morphinan-3,8-alpha-diol, 6,7-didehydro-4,5-alpha-epoxy-17-methyl-, acetate
CAS 63690-05-1C19H21NO4
Morphinan-3,8-beta-diol, 6,7-didehydro-4,5-alpha-epoxy-17-methyl-, acetate
CAS 63690-07-3C19H21NO4
Morphinan-3-ol, 6,7-didehydro-8-beta-diethylamino-4,5-alpha-epoxy-17-methyl-
CAS 63732-55-8C21H28N2O2
Morphinan-8-alpha-ol, 6,7-didehydro-4,5-alpha-epoxy-3-ethoxy-17-methyl-
CAS 63732-58-1C19H23NO3
Acetylallopseudocodeine
CAS 63732-60-5C20H23NO4
Acetylpseudocodeine
CAS 63732-61-6C20H23NO4
Allopseudocodeine hydrochloride
CAS 63732-62-7C18H22ClNO3
Desoxymorphine C
CAS 63732-65-0C17H19NO2
Morphinan-3-ol, 6,7-didehydro-4,5-alpha-epoxy-8-alpha-methoxy-17-methyl-
CAS 63813-36-5C18H21NO3
Pseudocodeine, hydrochloride
CAS 102043-42-5C18H22ClNO3
Thebacon
CAS 466-90-0C20H23NO4
Thebacon hydrochloride
CAS 20236-82-2C20H24ClNO4
8,14beta-Dihydrooripavine
CAS 873087-79-7C18H21NO3
- 8beta-(Bis(2-chloroethyl)amino)-6,7-didehydro-3-hydroxy-17-methyl-4,5alpha-epoxymorphinan90246-16-5C21H26Cl2N2O2
- delta6-Codeine-L-isoleucinate592541-33-8C24H32N2O4
- 8beta-Isothiocyanato-3-methoxy-17-methyl-5alpha-6,7-didehydro-4,5-epoxymorphinan38763-37-0C19H20N2O2S
- (4S,4aR,5R,7aS,12bS,13S)-3-Methyl-2,4,4a,5,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-5,9,13-triol1188377-79-8C17H19NO4
Related scaffolds
Same ring framework with different atoms or bond orders
C1=CC2C3Cc4cccc5c4C2(CCN3)C(C1)O563 chemicals
O=C1CCC2C3Cc4cccc5c4C2(CCN3)C1O547 chemicals
c1cc2c3c(c1)OC1CCCC4C(C2)NCCC31425 chemicals
O=C1C=CC2C3Cc4cccc5c4C2(CCN3)C1O57 chemicals
C1=CC2Oc3cccc4c3C23CCNC(C4)C3=C13 chemicals
O=C1c2cccc3c2C24CCNC1C2CCC(=O)C4O32 chemicals
O=C1CC=C2C3Cc4cccc5c4C2(CCN3)C1O51 chemical
C1=C2C3Cc4cccc5c4C2(CCN3)C(CC1)O51 chemical
O=C1c2cccc3c2C24CCNC1C2C=CCC4O31 chemical