CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 26 atoms

40 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
40
With full pages
2
Scaffold SMILES

O=c1c2ccccc2n(Cc2ccccc2)c(=O)n1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2ccccc2n(Cc2ccccc2)c(=O)n1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

1,3-Bis[(2-fluorophenyl)methyl]quinazoline-2,4-dione chemical structure, C22H16F2N2O2, CAS 634169-06-5
1,3-Bis[(2-fluorophenyl)methyl]quinazoline-2,4-dione
CAS 634169-06-5C22H16F2N2O2
3-Benzyl-1-(2-chlorobenzyl)quinazoline-2,4(1H,3H)-dione chemical structure, C22H17ClN2O2, CAS 866870-24-8
3-Benzyl-1-(2-chlorobenzyl)quinazoline-2,4(1H,3H)-dione
CAS 866870-24-8C22H17ClN2O2
3-Benzyl-1-(2,5-dimethylbenzyl)quinazoline-2,4(1H,3H)-dione chemical structure, C24H22N2O2, CAS 892271-19-1
3-Benzyl-1-(2,5-dimethylbenzyl)quinazoline-2,4(1H,3H)-dione
CAS 892271-19-1C24H22N2O2
3-Benzyl-1-[(4-nitrophenyl)methyl]-1,2,3,4-tetrahydroquinazoline-2,4-dione chemical structure, C22H17N3O4, CAS 666825-65-6
3-Benzyl-1-[(4-nitrophenyl)methyl]-1,2,3,4-tetrahydroquinazoline-2,4-dione
CAS 666825-65-6C22H17N3O4
3-Benzyl-1-[(2-chloro-4-fluorophenyl)methyl]-1,2,3,4-tetrahydroquinazoline-2,4-dione chemical structure, C22H16ClFN2O2, CAS 892270-50-7
3-Benzyl-1-[(2-chloro-4-fluorophenyl)methyl]-1,2,3,4-tetrahydroquinazoline-2,4-dione
CAS 892270-50-7C22H16ClFN2O2
4-((6,7-Dimethoxy-1-(3-methylbenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-methylbenzamide chemical structure, C27H27N3O5, CAS 1021261-92-6
4-((6,7-Dimethoxy-1-(3-methylbenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-methylbenzamide
CAS 1021261-92-6C27H27N3O5
N-(3-Methoxypropyl)-4-((1-(3-nitrobenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzamide chemical structure, C27H26N4O6, CAS 899920-60-6
N-(3-Methoxypropyl)-4-((1-(3-nitrobenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzamide
CAS 899920-60-6C27H26N4O6
N-(3-Methoxypropyl)-4-((1-(4-nitrobenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzamide chemical structure, C27H26N4O6, CAS 899920-71-9
N-(3-Methoxypropyl)-4-((1-(4-nitrobenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzamide
CAS 899920-71-9C27H26N4O6
4-((1-(2-Fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-pentylbenzamide chemical structure, C30H32FN3O5, CAS 1185171-81-6
4-((1-(2-Fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-pentylbenzamide
CAS 1185171-81-6C30H32FN3O5
4-((6,7-Dimethoxy-1-(2-methylbenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopentylbenzamide chemical structure, C31H35N3O5, CAS 1184986-75-1
4-((6,7-Dimethoxy-1-(2-methylbenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopentylbenzamide
CAS 1184986-75-1C31H35N3O5
4-((1-(2-Fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopentylbenzamide chemical structure, C30H32FN3O5, CAS 1189464-76-3
4-((1-(2-Fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopentylbenzamide
CAS 1189464-76-3C30H32FN3O5
4-((1-(2,5-Dimethylbenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopentylbenzamide chemical structure, C32H37N3O5, CAS 1189975-93-6
4-((1-(2,5-Dimethylbenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopentylbenzamide
CAS 1189975-93-6C32H37N3O5
4-((6,7-Dimethoxy-1-(3-methoxybenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopentylbenzamide chemical structure, C31H35N3O6, CAS 1189870-33-4
4-((6,7-Dimethoxy-1-(3-methoxybenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopentylbenzamide
CAS 1189870-33-4C31H35N3O6
4-((1-(2,5-Dimethylbenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-(2-methoxyethyl)benzamide chemical structure, C30H33N3O6, CAS 1215394-99-2
4-((1-(2,5-Dimethylbenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-(2-methoxyethyl)benzamide
CAS 1215394-99-2C30H33N3O6
4-((1-(2-Fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopropylbenzamide chemical structure, C28H28FN3O5, CAS 1185052-34-9
4-((1-(2-Fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopropylbenzamide
CAS 1185052-34-9C28H28FN3O5
4-{[6,7-Dimethoxy-1-(3-methylbenzyl)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl]methyl}-N-(2-methoxyethyl)benzamide chemical structure, C29H31N3O6, CAS 1184996-43-7
4-{[6,7-Dimethoxy-1-(3-methylbenzyl)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl]methyl}-N-(2-methoxyethyl)benzamide
CAS 1184996-43-7C29H31N3O6
4-({1-[(2,5-Dimethylphenyl)methyl]-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-propylbenzamide chemical structure, C30H33N3O5, CAS 1189938-94-0
4-({1-[(2,5-Dimethylphenyl)methyl]-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-propylbenzamide
CAS 1189938-94-0C30H33N3O5
N-Butyl-4-((1-(2-fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzamide chemical structure, C29H30FN3O5, CAS 1189912-32-0
N-Butyl-4-((1-(2-fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzamide
CAS 1189912-32-0C29H30FN3O5
4-((6,7-Dimethoxy-1-(3-methylbenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-propylbenzamide chemical structure, C29H31N3O5, CAS 1189643-71-7
4-((6,7-Dimethoxy-1-(3-methylbenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-propylbenzamide
CAS 1189643-71-7C29H31N3O5
4-((1-(2-Chloro-6-fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopropylbenzamide chemical structure, C28H27ClFN3O5, CAS 1184998-55-7
4-((1-(2-Chloro-6-fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-isopropylbenzamide
CAS 1184998-55-7C28H27ClFN3O5
4-((6,7-Dimethoxy-1-(2-methylbenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-(3-methoxypropyl)benzamide chemical structure, C30H33N3O6, CAS 1215503-70-0
4-((6,7-Dimethoxy-1-(2-methylbenzyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-(3-methoxypropyl)benzamide
CAS 1215503-70-0C30H33N3O6
4-((1-(5-Formyl-2-methoxybenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-propylbenzamide chemical structure, C30H31N3O7, CAS 1223825-66-8
4-((1-(5-Formyl-2-methoxybenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-propylbenzamide
CAS 1223825-66-8C30H31N3O7
N-Butyl-4-((1-(2,5-dimethylbenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzamide chemical structure, C31H35N3O5, CAS 1215808-25-5
N-Butyl-4-((1-(2,5-dimethylbenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzamide
CAS 1215808-25-5C31H35N3O5
4-((1-(2-Fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-(3-methoxypropyl)benzamide chemical structure, C29H30FN3O6, CAS 1216616-61-3
4-((1-(2-Fluorobenzyl)-6,7-dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-(3-methoxypropyl)benzamide
CAS 1216616-61-3C29H30FN3O6