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Murcko scaffold

Ring system with 4 rings and 25 atoms

56 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 25
Chemicals: 56
With full pages: 1

Scaffold SMILES

O=C(c1cc(Nc2ccccc2)c2ccccc2n1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(c1cc(Nc2ccccc2)c2ccccc2n1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 56 chemicals

(4-((3,4-Dimethoxyphenyl)amino)-8-methoxyquinolin-2-yl)(piperidin-1-yl)methanone chemical structure, C24H27N3O4, CAS 1251629-97-6

(4-((3,4-Dimethoxyphenyl)amino)-8-methoxyquinolin-2-yl)(piperidin-1-yl)methanone

CAS 1251629-97-6C₂₄H₂₇N₃O₄

N-(3-Chloro-4-methylphenyl)-8-methoxy-2-(piperidine-1-carbonyl)quinolin-4-amine chemical structure, C23H24ClN3O2, CAS 1251600-19-7

N-(3-Chloro-4-methylphenyl)-8-methoxy-2-(piperidine-1-carbonyl)quinolin-4-amine

CAS 1251600-19-7C₂₃H₂₄ClN₃O₂

N-(4-Ethoxyphenyl)-8-methoxy-2-(piperidine-1-carbonyl)quinolin-4-amine chemical structure, C24H27N3O3, CAS 1251688-22-8

N-(4-Ethoxyphenyl)-8-methoxy-2-(piperidine-1-carbonyl)quinolin-4-amine

CAS 1251688-22-8C₂₄H₂₇N₃O₃

(4-((4-Bromophenyl)amino)-8-methoxyquinolin-2-yl)(piperidin-1-yl)methanone chemical structure, C22H22BrN3O2, CAS 1251566-41-2

(4-((4-Bromophenyl)amino)-8-methoxyquinolin-2-yl)(piperidin-1-yl)methanone

CAS 1251566-41-2C₂₂H₂₂BrN₃O₂

N-(3,4-Difluorophenyl)-8-methoxy-2-(piperidine-1-carbonyl)quinolin-4-amine chemical structure, C22H21F2N3O2, CAS 1251597-07-5

N-(3,4-Difluorophenyl)-8-methoxy-2-(piperidine-1-carbonyl)quinolin-4-amine

CAS 1251597-07-5C₂₂H₂₁F₂N₃O₂

(4-((4-Ethylphenyl)amino)-8-methoxyquinolin-2-yl)(piperidin-1-yl)methanone chemical structure, C24H27N3O2, CAS 1251706-07-6

(4-((4-Ethylphenyl)amino)-8-methoxyquinolin-2-yl)(piperidin-1-yl)methanone

CAS 1251706-07-6C₂₄H₂₇N₃O₂

N-(3,5-Dimethoxyphenyl)-8-methoxy-2-(piperidine-1-carbonyl)quinolin-4-amine chemical structure, C24H27N3O4, CAS 1251580-48-9

N-(3,5-Dimethoxyphenyl)-8-methoxy-2-(piperidine-1-carbonyl)quinolin-4-amine

CAS 1251580-48-9C₂₄H₂₇N₃O₄

(8-Methoxy-4-((3-(methylthio)phenyl)amino)quinolin-2-yl)(piperidin-1-yl)methanone chemical structure, C23H25N3O2S, CAS 1251600-26-6

(8-Methoxy-4-((3-(methylthio)phenyl)amino)quinolin-2-yl)(piperidin-1-yl)methanone

CAS 1251600-26-6C₂₃H₂₅N₃O₂S

(4-((3-Methoxyphenyl)amino)quinolin-2-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C23H25N3O2, CAS 1251634-57-7

(4-((3-Methoxyphenyl)amino)quinolin-2-yl)(4-methylpiperidin-1-yl)methanone

CAS 1251634-57-7C₂₃H₂₅N₃O₂

(4-((3-Chloro-4-methoxyphenyl)amino)quinolin-2-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C23H24ClN3O2, CAS 1251669-74-5

(4-((3-Chloro-4-methoxyphenyl)amino)quinolin-2-yl)(4-methylpiperidin-1-yl)methanone

CAS 1251669-74-5C₂₃H₂₄ClN₃O₂

(4-((5-Chloro-2,4-dimethoxyphenyl)amino)quinolin-2-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C24H26ClN3O3, CAS 1251710-43-6

(4-((5-Chloro-2,4-dimethoxyphenyl)amino)quinolin-2-yl)(4-methylpiperidin-1-yl)methanone

CAS 1251710-43-6C₂₄H₂₆ClN₃O₃

(4-((2,4-Dimethoxyphenyl)amino)quinolin-2-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C24H27N3O3, CAS 1251633-40-5

(4-((2,4-Dimethoxyphenyl)amino)quinolin-2-yl)(4-methylpiperidin-1-yl)methanone

CAS 1251633-40-5C₂₄H₂₇N₃O₃

Ethyl 3-{[2-(4-methylpiperidine-1-carbonyl)quinolin-4-yl]amino}benzoate chemical structure, C25H27N3O3, CAS 1226453-83-3

Ethyl 3-{[2-(4-methylpiperidine-1-carbonyl)quinolin-4-yl]amino}benzoate

CAS 1226453-83-3C₂₅H₂₇N₃O₃

N-(4-Fluorophenyl)-6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-amine chemical structure, C23H24FN3O, CAS 1226435-79-5

N-(4-Fluorophenyl)-6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-amine

CAS 1226435-79-5C₂₃H₂₄FN₃O

N-(2-Methoxyphenyl)-6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-amine chemical structure, C24H27N3O2, CAS 1251670-39-9

N-(2-Methoxyphenyl)-6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-amine

CAS 1251670-39-9C₂₄H₂₇N₃O₂

N-(2-Ethoxyphenyl)-6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-amine chemical structure, C25H29N3O2, CAS 1251588-11-0

N-(2-Ethoxyphenyl)-6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-amine

CAS 1251588-11-0C₂₅H₂₉N₃O₂

(4-((2,4-Dimethoxyphenyl)amino)-6-methylquinolin-2-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C25H29N3O3, CAS 1251618-72-0

(4-((2,4-Dimethoxyphenyl)amino)-6-methylquinolin-2-yl)(4-methylpiperidin-1-yl)methanone

CAS 1251618-72-0C₂₅H₂₉N₃O₃

1-(4-Methoxyphenyl)-4-[(1-pyridin-4-ylpiperidin-3-yl)carbonyl]piperazine chemical structure, C25H29N3O3, CAS 1251558-64-1

1-(4-Methoxyphenyl)-4-[(1-pyridin-4-ylpiperidin-3-yl)carbonyl]piperazine

CAS 1251558-64-1C₂₅H₂₉N₃O₃

(4-((3,5-Dimethoxyphenyl)amino)-6-methylquinolin-2-yl)(3-methylpiperidin-1-yl)methanone chemical structure, C25H29N3O3, CAS 1251580-43-4

(4-((3,5-Dimethoxyphenyl)amino)-6-methylquinolin-2-yl)(3-methylpiperidin-1-yl)methanone

CAS 1251580-43-4C₂₅H₂₉N₃O₃

N-(3,5-Dimethylphenyl)-6,7-dimethoxy-2-(3-methylpiperidine-1-carbonyl)quinolin-4-amine chemical structure, C26H31N3O3, CAS 1251635-57-0

N-(3,5-Dimethylphenyl)-6,7-dimethoxy-2-(3-methylpiperidine-1-carbonyl)quinolin-4-amine

CAS 1251635-57-0C₂₆H₃₁N₃O₃

(6,7-Dimethoxy-4-((3-methoxyphenyl)amino)quinolin-2-yl)(3-methylpiperidin-1-yl)methanone chemical structure, C25H29N3O4, CAS 1251689-09-4

(6,7-Dimethoxy-4-((3-methoxyphenyl)amino)quinolin-2-yl)(3-methylpiperidin-1-yl)methanone

CAS 1251689-09-4C₂₅H₂₉N₃O₄

N-(3-Ethylphenyl)-6,7-dimethoxy-2-(3-methylpiperidine-1-carbonyl)quinolin-4-amine chemical structure, C26H31N3O3, CAS 1251582-23-6

N-(3-Ethylphenyl)-6,7-dimethoxy-2-(3-methylpiperidine-1-carbonyl)quinolin-4-amine

CAS 1251582-23-6C₂₆H₃₁N₃O₃

N-(4-Ethylphenyl)-6,7-dimethoxy-2-(3-methylpiperidine-1-carbonyl)quinolin-4-amine chemical structure, C26H31N3O3, CAS 1251580-90-1

N-(4-Ethylphenyl)-6,7-dimethoxy-2-(3-methylpiperidine-1-carbonyl)quinolin-4-amine

CAS 1251580-90-1C₂₆H₃₁N₃O₃

(4-((3-Chlorophenyl)amino)-6-methylquinolin-2-yl)(piperidin-1-yl)methanone chemical structure, C22H22ClN3O, CAS 1226456-29-6

(4-((3-Chlorophenyl)amino)-6-methylquinolin-2-yl)(piperidin-1-yl)methanone

CAS 1226456-29-6C₂₂H₂₂ClN₃O