CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 23 atoms

23 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
23
With full pages
2
Scaffold SMILES

O=c1c2ccccc2oc2cc(OCc3ccccc3)ccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2ccccc2oc2cc(OCc3ccccc3)ccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

1-Hydroxy-3-phenylmethoxyxanthen-9-one chemical structure, C20H14O4, CAS 831228-90-1
1-Hydroxy-3-phenylmethoxyxanthen-9-one
CAS 831228-90-1C20H14O4
Methyl 4-{[(1-hydroxy-9-oxo-9H-xanthen-3-yl)oxy]methyl}benzoate chemical structure, C22H16O6, CAS 831232-70-3
Methyl 4-{[(1-hydroxy-9-oxo-9H-xanthen-3-yl)oxy]methyl}benzoate
CAS 831232-70-3C22H16O6
1-Hydroxy-3-[(4-nitrophenyl)methoxy]xanthen-9-one chemical structure, C20H13NO6, CAS 879469-41-7
1-Hydroxy-3-[(4-nitrophenyl)methoxy]xanthen-9-one
CAS 879469-41-7C20H13NO6
3-[(4-Bromobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H13BrO4, CAS 859658-97-2
3-[(4-Bromobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 859658-97-2C20H13BrO4
1-Hydroxy-3-[(4-vinylbenzyl)oxy]-9H-xanthen-9-one chemical structure, C22H16O4, CAS 859662-78-5
1-Hydroxy-3-[(4-vinylbenzyl)oxy]-9H-xanthen-9-one
CAS 859662-78-5C22H16O4
4-{[(1-Hydroxy-9-oxo-9H-xanthen-3-yl)oxy]methyl}benzoic acid chemical structure, C21H14O6, CAS 859666-21-0
4-{[(1-Hydroxy-9-oxo-9H-xanthen-3-yl)oxy]methyl}benzoic acid
CAS 859666-21-0C21H14O6
3-[(3,4-Dichlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H12Cl2O4, CAS 896064-81-6
3-[(3,4-Dichlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 896064-81-6C20H12Cl2O4
3-[(2,6-Difluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H12F2O4, CAS 896080-83-4
3-[(2,6-Difluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 896080-83-4C20H12F2O4
3-[(2-Fluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H13FO4, CAS 896600-53-6
3-[(2-Fluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 896600-53-6C20H13FO4
3-[(3-Fluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H13FO4, CAS 896832-00-1
3-[(3-Fluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 896832-00-1C20H13FO4
3-[(2-Chloro-6-fluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H12ClFO4, CAS 896856-01-2
3-[(2-Chloro-6-fluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 896856-01-2C20H12ClFO4
3-[(2,4-Dichlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H12Cl2O4, CAS 899401-24-2
3-[(2,4-Dichlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 899401-24-2C20H12Cl2O4
3-[(2,6-Dichlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H12Cl2O4, CAS 899387-01-0
3-[(2,6-Dichlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 899387-01-0C20H12Cl2O4
3-[(3-Chlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H13ClO4, CAS 899407-15-9
3-[(3-Chlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 899407-15-9C20H13ClO4
1-Hydroxy-3-{[3-(trifluoromethyl)benzyl]oxy}-9H-xanthen-9-one chemical structure, C21H13F3O4, CAS 899413-88-8
1-Hydroxy-3-{[3-(trifluoromethyl)benzyl]oxy}-9H-xanthen-9-one
CAS 899413-88-8C21H13F3O4
3-[(2,4-Difluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H12F2O4, CAS 899390-40-0
3-[(2,4-Difluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 899390-40-0C20H12F2O4
3-[(4-Bromo-2-fluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H12BrFO4, CAS 900269-21-8
3-[(4-Bromo-2-fluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 900269-21-8C20H12BrFO4
3-[(3-Bromobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H13BrO4, CAS 900271-35-4
3-[(3-Bromobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 900271-35-4C20H13BrO4
3-[(4-Chlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H13ClO4, CAS 900272-89-1
3-[(4-Chlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 900272-89-1C20H13ClO4
3-[(2-Chlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H13ClO4, CAS 900283-74-1
3-[(2-Chlorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 900283-74-1C20H13ClO4
3-[(4-Fluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one chemical structure, C20H13FO4, CAS 900297-32-7
3-[(4-Fluorobenzyl)oxy]-1-hydroxy-9H-xanthen-9-one
CAS 900297-32-7C20H13FO4
[3-(Benzyloxy)-1,5-dimethoxy-9-oxo-9H-xanthen-4-yl]acetaldehyde chemical structure, C24H20O6, CAS 106092-52-8
[3-(Benzyloxy)-1,5-dimethoxy-9-oxo-9H-xanthen-4-yl]acetaldehyde
CAS 106092-52-8C24H20O6
3-Chloro-6-(phenylmethoxy)-9H-xanthen-9-one chemical structure, C20H13ClO3, CAS 1476767-02-8
3-Chloro-6-(phenylmethoxy)-9H-xanthen-9-one
CAS 1476767-02-8C20H13ClO3