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Murcko scaffold

Ring system with 3 rings and 20 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
12
With full pages
7
Scaffold SMILES

O=C1C=C(N2CCCCCC2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=C(N2CCCCCC2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

3-(Azepan-1-yl)-4-chloro-1-(2,4-dimethylphenyl)pyrrole-2,5-dione chemical structure, C18H21ClN2O2, CAS 307528-21-8
3-(Azepan-1-yl)-4-chloro-1-(2,4-dimethylphenyl)pyrrole-2,5-dione
CAS 307528-21-8C18H21ClN2O2
3-(1-Azepanyl)-4-chloro-1-(2-methylphenyl)pyrrole-2,5-dione chemical structure, C17H19ClN2O2, CAS 347365-13-3
3-(1-Azepanyl)-4-chloro-1-(2-methylphenyl)pyrrole-2,5-dione
CAS 347365-13-3C17H19ClN2O2
3-(Azepan-1-yl)-4-chloro-1-phenylpyrrole-2,5-dione chemical structure, C16H17ClN2O2, CAS 303034-18-6
3-(Azepan-1-yl)-4-chloro-1-phenylpyrrole-2,5-dione
CAS 303034-18-6C16H17ClN2O2
3-(Azepan-1-yl)-4-chloro-1-(2-chlorophenyl)pyrrole-2,5-dione chemical structure, C16H16Cl2N2O2, CAS 303035-94-1
3-(Azepan-1-yl)-4-chloro-1-(2-chlorophenyl)pyrrole-2,5-dione
CAS 303035-94-1C16H16Cl2N2O2
3-(1-Azepanyl)-4-chloro-1-(2,4-dichlorophenyl)-1H-pyrrole-2,5-dione chemical structure, C16H15Cl3N2O2, CAS 307533-11-5
3-(1-Azepanyl)-4-chloro-1-(2,4-dichlorophenyl)-1H-pyrrole-2,5-dione
CAS 307533-11-5C16H15Cl3N2O2
3-(Azepan-1-yl)-4-chloro-1-(3-chloro-4-methylphenyl)pyrrole-2,5-dione chemical structure, C17H18Cl2N2O2, CAS 307534-34-5
3-(Azepan-1-yl)-4-chloro-1-(3-chloro-4-methylphenyl)pyrrole-2,5-dione
CAS 307534-34-5C17H18Cl2N2O2
3-(Azepan-1-yl)-4-chloro-1-(4-iodophenyl)pyrrole-2,5-dione chemical structure, C16H16ClIN2O2, CAS 370847-02-2
3-(Azepan-1-yl)-4-chloro-1-(4-iodophenyl)pyrrole-2,5-dione
CAS 370847-02-2C16H16ClIN2O2
RefChem:345389 chemical structure, C16H16BrClN2O2, CAS 6141-10-2
RefChem:345389
CAS 6141-10-2C16H16BrClN2O2
3-(Azepan-1-yl)-4-chloro-1-(4-methoxyphenyl)pyrrole-2,5-dione chemical structure, C17H19ClN2O3, CAS 6869-98-3
3-(Azepan-1-yl)-4-chloro-1-(4-methoxyphenyl)pyrrole-2,5-dione
CAS 6869-98-3C17H19ClN2O3
3-(Azepan-1-yl)-4-chloro-1-(4-ethylphenyl)pyrrole-2,5-dione chemical structure, C18H21ClN2O2, CAS 385372-98-5
3-(Azepan-1-yl)-4-chloro-1-(4-ethylphenyl)pyrrole-2,5-dione
CAS 385372-98-5C18H21ClN2O2
3-(Azepan-1-yl)-1-(4-chlorophenyl)-1H-pyrrole-2,5-dione chemical structure, C16H17ClN2O2, CAS 879617-88-6
3-(Azepan-1-yl)-1-(4-chlorophenyl)-1H-pyrrole-2,5-dione
CAS 879617-88-6C16H17ClN2O2
3-(Azepan-1-yl)-4-chloro-1-[4-(trifluoromethyl)phenyl]pyrrole-2,5-dione chemical structure, C17H16ClF3N2O2, CAS 2116281-10-6
3-(Azepan-1-yl)-4-chloro-1-[4-(trifluoromethyl)phenyl]pyrrole-2,5-dione
CAS 2116281-10-6C17H16ClF3N2O2