Murcko scaffold
Thiazolo[4,5-c]pyridine scaffold
114 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 114
- With full pages
- 15
Scaffold SMILES
c1cc2scnc2cn1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 114 chemicals
![4-Chloro-2-methylthiazolo[4,5-c]pyridine chemical structure, C7H5ClN2S, CAS 936477-32-6](/s/NOTDCNMHEDSELY-UHFFFAOYSA-N.svg)
4-Chloro-2-methylthiazolo[4,5-c]pyridine
CAS 936477-32-6C7H5ClN2S
![4-Chloro-6-methylthiazolo[4,5-c]pyridine chemical structure, C7H5ClN2S, CAS 1159829-49-8](/s/MWUPZCDPJVKEKK-UHFFFAOYSA-N.svg)
4-Chloro-6-methylthiazolo[4,5-c]pyridine
CAS 1159829-49-8C7H5ClN2S
![4-Chloro-7-iodo-2-methylthiazolo[4,5-c]pyridine chemical structure, C7H4ClIN2S, CAS 936477-39-3](/s/IXYMWQKZWIDERD-UHFFFAOYSA-N.svg)
4-Chloro-7-iodo-2-methylthiazolo[4,5-c]pyridine
CAS 936477-39-3C7H4ClIN2S
![6-Bromothiazolo[4,5-c]pyridine chemical structure, C6H3BrN2S, CAS 1234014-66-4](/s/BNWBITZLSRCTRO-UHFFFAOYSA-N.svg)
6-Bromothiazolo[4,5-c]pyridine
CAS 1234014-66-4C6H3BrN2S
![Thiazolo[4,5-c]pyridine-2-acetic acid,4-chloro-6-methyl- chemical structure, C9H7ClN2O2S, CAS 1242251-41-7](/s/ZQPCSYCJGSYBKR-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-2-acetic acid,4-chloro-6-methyl-
CAS 1242251-41-7C9H7ClN2O2S
![Methyl 4-chloro-[1,3]thiazolo[4,5-c]pyridine-2-carboxylate chemical structure, C8H5ClN2O2S, CAS 1206248-76-1](/s/MINXZBXOLYOJOY-UHFFFAOYSA-N.svg)
Methyl 4-chloro-[1,3]thiazolo[4,5-c]pyridine-2-carboxylate
CAS 1206248-76-1C8H5ClN2O2S
![Thiazolo[4,5-c]pyridine-2-carboxylic acid,4-chloro-6-methyl-,methyl ester chemical structure, C9H7ClN2O2S, CAS 1242255-42-0](/s/DNBFDCYQJWTGFX-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-2-carboxylic acid,4-chloro-6-methyl-,methyl ester
CAS 1242255-42-0C9H7ClN2O2S
![Methyl 6-chloro-[1,3]thiazolo[4,5-c]pyridine-2-carboxylate chemical structure, C8H5ClN2O2S, CAS 1206248-19-2](/s/ULIITBVQPIVXQK-UHFFFAOYSA-N.svg)
Methyl 6-chloro-[1,3]thiazolo[4,5-c]pyridine-2-carboxylate
CAS 1206248-19-2C8H5ClN2O2S
![Thiazolo[4,5-c]pyridine-2-propanoic acid,4-chloro- chemical structure, C9H7ClN2O2S, CAS 1242257-01-7](/s/RVGAQZLNTWKNBF-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-2-propanoic acid,4-chloro-
CAS 1242257-01-7C9H7ClN2O2S
![Thiazolo[4,5-c]pyridine-4-carboxylic acid chemical structure, C7H4N2O2S, CAS 1159830-64-4](/s/CGLNOYDYCHTDTJ-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-4-carboxylic acid
CAS 1159830-64-4C7H4N2O2S
![Thiazolo[4,5-c]pyridine-4-carboxylic acid,2-(1-methylethyl)-,methyl ester chemical structure, C11H12N2O2S, CAS 1242256-01-4](/s/OYPUCLCJCFJDMN-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-4-carboxylic acid,2-(1-methylethyl)-,methyl ester
CAS 1242256-01-4C11H12N2O2S
![Thiazolo[4,5-c]pyridine-4-carboxylic acid,2,6-dimethyl-,methyl ester chemical structure, C10H10N2O2S, CAS 1242248-95-8](/s/VOHPMBCSKVFDCE-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-4-carboxylic acid,2,6-dimethyl-,methyl ester
CAS 1242248-95-8C10H10N2O2S
![Thiazolo[4,5-c]pyridine-4-carboxylic acid,2-amino-6-bromo-,methyl ester chemical structure, C8H6BrN3O2S, CAS 1206248-26-1](/s/BFSMOAYVWVBZJA-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-4-carboxylic acid,2-amino-6-bromo-,methyl ester
CAS 1206248-26-1C8H6BrN3O2S
![Thiazolo[4,5-c]pyridine-4-carboxylic acid,2-ethyl-,methyl ester chemical structure, C10H10N2O2S, CAS 1242250-24-3](/s/ZSRUSCPBIPIFTN-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-4-carboxylic acid,2-ethyl-,methyl ester
CAS 1242250-24-3C10H10N2O2S
![Thiazolo[4,5-c]pyridine-4-carboxylic acid,2-ethyl-6-methyl-,methyl ester chemical structure, C11H12N2O2S, CAS 1242255-99-7](/s/HKFOZCJFBCTMJJ-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-4-carboxylic acid,2-ethyl-6-methyl-,methyl ester
CAS 1242255-99-7C11H12N2O2S
![2-Aminothiazolo[4,5-c]pyridine-6-carbonitrile chemical structure, C7H4N4S, CAS 1206249-96-8](/s/JAQFYSYJWOFNDX-UHFFFAOYSA-N.svg)
2-Aminothiazolo[4,5-c]pyridine-6-carbonitrile
CAS 1206249-96-8C7H4N4S
![Methyl thiazolo[4,5-c]pyridine-6-carboxylate chemical structure, C8H6N2O2S, CAS 1206973-17-2](/s/HNNSZAPLWHCQLY-UHFFFAOYSA-N.svg)
Methyl thiazolo[4,5-c]pyridine-6-carboxylate
CAS 1206973-17-2C8H6N2O2S
![Thiazolo[4,5-c]pyridine-6-carboxylic acid,2-(1-methylethyl)-,methyl ester chemical structure, C11H12N2O2S, CAS 1206983-83-6](/s/VAAIPHGALZCWFM-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-6-carboxylic acid,2-(1-methylethyl)-,methyl ester
CAS 1206983-83-6C11H12N2O2S
![Thiazolo[4,5-c]pyridine-6-carboxylic acid,2-(diethylamino)-,methyl ester chemical structure, C12H15N3O2S, CAS 1206972-54-4](/s/FOKBJRWAVAUEIH-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-6-carboxylic acid,2-(diethylamino)-,methyl ester
CAS 1206972-54-4C12H15N3O2S
![Thiazolo[4,5-c]pyridine-6-carboxylic acid,2-(dimethylamino)-,methyl ester chemical structure, C10H11N3O2S, CAS 1206974-65-3](/s/BKXDUJOUWPIBJT-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-6-carboxylic acid,2-(dimethylamino)-,methyl ester
CAS 1206974-65-3C10H11N3O2S
![Thiazolo[4,5-c]pyridine-6-carboxylic acid,2-(methylamino)-,methyl ester chemical structure, C9H9N3O2S, CAS 1206975-37-2](/s/NEEOQNYPUHVAQR-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-6-carboxylic acid,2-(methylamino)-,methyl ester
CAS 1206975-37-2C9H9N3O2S
![Methyl 2-aminothiazolo[4,5-c]pyridine-6-carboxylate chemical structure, C8H7N3O2S, CAS 1206248-06-7](/s/DWQFUBMPDULNGL-UHFFFAOYSA-N.svg)
Methyl 2-aminothiazolo[4,5-c]pyridine-6-carboxylate
CAS 1206248-06-7C8H7N3O2S
![Methyl 2-bromo-[1,3]thiazolo[4,5-c]pyridine-6-carboxylate chemical structure, C8H5BrN2O2S, CAS 1206250-25-0](/s/IBMYTYUNYBDXRX-UHFFFAOYSA-N.svg)
Methyl 2-bromo-[1,3]thiazolo[4,5-c]pyridine-6-carboxylate
CAS 1206250-25-0C8H5BrN2O2S
![Thiazolo[4,5-c]pyridine-6-carboxylic acid,2-ethyl-,methyl ester chemical structure, C10H10N2O2S, CAS 1206977-74-3](/s/RJBJBTWCKRAVJX-UHFFFAOYSA-N.svg)
Thiazolo[4,5-c]pyridine-6-carboxylic acid,2-ethyl-,methyl ester
CAS 1206977-74-3C10H10N2O2S
- Methyl 2-{[1,3]thiazolo[4,5-c]pyridin-2-yl}acetate1507632-76-9C9H8N2O2S
- 2-Bromothiazolo[4,5-c]pyridine1508002-59-2C6H3BrN2S
- Methyl thiazolo[4,5-c]pyridine-2-carboxylate1089315-24-1C8H6N2O2S
- 4,6-Dimethylthiazolo[4,5-c]pyridin-2-amine115192-30-8C8H9N3S
- 4,6-Dichlorothiazolo[4,5-c]pyridine1822973-55-6C6H2Cl2N2S
- tert-Butyl N-({[1,3]thiazolo[4,5-c]pyridin-2-yl}methyl)carbamate1203605-31-5C12H15N3O2S
- 7-Bromo-(1,3)thiazolo(4,5-c)pyridin-2-amine118801-75-5C6H4BrN3S
- 7-Bromothiazolo[4,5-c]pyridine108724-09-0C6H3BrN2S
- Thiazolo[4,5-c]pyridine-2-acetonitrile1620726-90-0C8H5N3S
- N-(Propan-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine2097925-95-4C9H11N3S
- Methyl 4,6-dichlorothiazolo[4,5-c]pyridine-2-carboxylate1824580-52-0C8H4Cl2N2O2S
- Thiazolo[4,5-c]pyridine, 2-bromo-4,6-dichloro-1824580-68-8C6HBrCl2N2S
- 4,6-Dichloro-2-methylthiazolo[4,5-c]pyridine1824623-31-5C7H4Cl2N2S
- Ethyl 4-chlorothiazolo[4,5-c]pyridine-2-carboxylate2090188-06-8C9H7ClN2O2S
- 3,3-Dimethyl-1-(thiazolo[4,5-c]pyridin-2-ylthio)butan-2-one2140463-99-4C12H14N2OS2
- 7-Bromo-2-chlorothiazolo[4,5-c]pyridine2384320-41-4C6H2BrClN2S
- 2-Methyl-[1,3]thiazolo[4,5-c]pyridine hydrochloride1082684-56-7C7H7ClN2S
- {[1,3]Thiazolo[4,5-c]pyridin-2-yl}methanamine dihydrochloride2044835-56-3C7H9Cl2N3S
- 7-Bromo-2-(methylthio)thiazolo[4,5-c]pyridine117890-78-5C7H5BrN2S2
- 7-Bromo-2-methylthiazolo[4,5-c]pyridine117890-79-6C7H5BrN2S
- Ethyl 7-bromothiazolo[4,5-c]pyridine-2-carboxylate2054338-96-2C9H7BrN2O2S
- (E)-4-(Dimethylamino)-N-([1,3]thiazolo[4,5-c]pyridin-2-ylmethyl)but-2-enamide2411335-18-5C13H16N4OS
- N-([1,3]Thiazolo[4,5-c]pyridin-2-ylmethyl)but-2-ynamide2411292-11-8C11H9N3OS
- N-(Thiazolo[4,5-c]pyridin-2-yl)hydroxylamine2273475-74-2C6H5N3OS
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc2[nH]ccc2c1](/scaffold/SIKJAQJRHWYJAI-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ccc2c12,455 chemicals![Scaffold c1ccc2[nH]cnc2c1](/scaffold/HYZJCKYKOHLVJF-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]cnc2c11,206 chemicals![Scaffold c1ccc2[nH]ncc2c1](/scaffold/BAXOFTOLAUCFNW-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ncc2c1795 chemicals
c1ccc2scnc2c1756 chemicals
c1ccc2occc2c1632 chemicals
c1ccc2c(c1)CCC2621 chemicals
c1ccc2c(c1)OCO2536 chemicals
c1ccc2sccc2c1529 chemicals
c1ccn2ccnc2c1525 chemicals
c1ccc2c(c1)CCN2440 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]cnc2[nH]1](/scaffold/LRFVTYWOQMYALW-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]cnc2[nH]1411 chemicals
O=C1NC(=O)c2ccccc21352 chemicals