CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 22 atoms

15 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
15
With full pages
3
Scaffold SMILES

O=C1CCCc2nc(Nc3ncc4ccccc4n3)ncc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCc2nc(Nc3ncc4ccccc4n3)ncc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

2-[(4,6-Dimethylquinazolin-2-yl)amino]-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H21N5O, CAS 443322-33-6
2-[(4,6-Dimethylquinazolin-2-yl)amino]-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one
CAS 443322-33-6C20H21N5O
7,7-Dimethyl-2-[(4-methylquinazolin-2-yl)amino]-6,8-dihydroquinazolin-5-one chemical structure, C19H19N5O, CAS 511514-73-1
7,7-Dimethyl-2-[(4-methylquinazolin-2-yl)amino]-6,8-dihydroquinazolin-5-one
CAS 511514-73-1C19H19N5O
6H-Quinazolin-5-one, 2-(6-methoxy-4-methylquinazolin-2-ylamino)-7,8-dihydro- chemical structure, C18H17N5O2, CAS 511514-38-8
6H-Quinazolin-5-one, 2-(6-methoxy-4-methylquinazolin-2-ylamino)-7,8-dihydro-
CAS 511514-38-8C18H17N5O2
2-[(4,7-Dimethylquinazolin-2-yl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C18H17N5O, CAS 511514-68-4
2-[(4,7-Dimethylquinazolin-2-yl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 511514-68-4C18H17N5O
2-[(4,6,7-Trimethylquinazolin-2-yl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H19N5O, CAS 511514-69-5
2-[(4,6,7-Trimethylquinazolin-2-yl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 511514-69-5C19H19N5O
2-(6-Ethyl-4-methyl-quinazolin-2-ylamino)-7,8-dihydro-6H-quinazolin-5-one chemical structure, C19H19N5O, CAS 511514-70-8
2-(6-Ethyl-4-methyl-quinazolin-2-ylamino)-7,8-dihydro-6H-quinazolin-5-one
CAS 511514-70-8C19H19N5O
2-[(6-Ethoxy-4-methylquinazolin-2-yl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H19N5O2, CAS 511514-71-9
2-[(6-Ethoxy-4-methylquinazolin-2-yl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 511514-71-9C19H19N5O2
2-[(4,8-Dimethylquinazolin-2-yl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C18H17N5O, CAS 714933-19-4
2-[(4,8-Dimethylquinazolin-2-yl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 714933-19-4C18H17N5O
2-[(4,8-Dimethylquinazolin-2-yl)amino]-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H21N5O, CAS 714926-72-4
2-[(4,8-Dimethylquinazolin-2-yl)amino]-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one
CAS 714926-72-4C20H21N5O
2-[(6-Ethoxy-4-methylquinazolin-2-yl)amino]-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H23N5O2, CAS 511514-72-0
2-[(6-Ethoxy-4-methylquinazolin-2-yl)amino]-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one
CAS 511514-72-0C21H23N5O2
7,7-Dimethyl-2-[(4,6,7-trimethylquinazolin-2-yl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H23N5O, CAS 524057-13-4
7,7-Dimethyl-2-[(4,6,7-trimethylquinazolin-2-yl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 524057-13-4C21H23N5O
2-((6-Methoxy-4-methylquinazolin-2-yl)amino)-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H21N5O2, CAS 524057-12-3
2-((6-Methoxy-4-methylquinazolin-2-yl)amino)-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one
CAS 524057-12-3C20H21N5O2
7-Methyl-2-[(4-methyl-2-quinazolinyl)amino]-7,8-dihydro-5(6H)-quinazolinone chemical structure, C18H17N5O, CAS 836663-18-4
7-Methyl-2-[(4-methyl-2-quinazolinyl)amino]-7,8-dihydro-5(6H)-quinazolinone
CAS 836663-18-4C18H17N5O
2-[(4,6-Dimethylquinazolin-2-yl)amino]-7-methyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H19N5O, CAS 925009-46-7
2-[(4,6-Dimethylquinazolin-2-yl)amino]-7-methyl-7,8-dihydroquinazolin-5(6H)-one
CAS 925009-46-7C19H19N5O
4-Methyl-2-[(6-methylquinazolin-2-yl)amino]-6,7,8-trihydroquinazolin-5-one chemical structure, C18H17N5O, CAS 1030553-58-2
4-Methyl-2-[(6-methylquinazolin-2-yl)amino]-6,7,8-trihydroquinazolin-5-one
CAS 1030553-58-2C18H17N5O