Murcko scaffold
1,2-Di(pyridin-3-yl)ethanone scaffold
8 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 8
- With full pages
- 1
Scaffold SMILES
O=C(Cc1cccnc1)c1cccnc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 8 of 8 chemicals
Metyrapone
CAS 54-36-4C14H14N2O
Metyrapone N-oxide
CAS 63473-06-3C14H14N2O2
1,2-Di(pyridin-3-yl)ethanone
CAS 6339-93-1C12H10N2O
1-Propanone, 2-methyl-1,2-di-3-pyridinyl-, hydrochloride
CAS 22752-91-6C14H15ClN2O
2-Methyl-1-(1-oxo-1lambda~5~-pyridin-3-yl)-2-(pyridin-3-yl)propan-1-one
CAS 71539-51-0C14H14N2O2
2-Methyl-2-(4-nitro-1-oxo-1lambda~5~-pyridin-3-yl)-1-(pyridin-3-yl)propan-1-one
CAS 63473-08-5C14H13N3O4
2-(4-Bromopyridin-3-yl)-2-methyl-1-(pyridin-3-yl)propan-1-one
CAS 86303-11-9C14H13BrN2O
Metyrapone tartrate
CAS 908-35-0C22H26N2O13