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Murcko scaffold

Spiro[cyclopropane-1,9'-fluorene] scaffold

22 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
15
Chemicals
22
With full pages
3
Scaffold SMILES

c1ccc2c(c1)-c1ccccc1C21CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Spiro[cyclopropane-1,9'-fluorene] page
Murcko scaffold c1ccc2c(c1)-c1ccccc1C21CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

2-Bromospiro[cyclopropane-1,9'-fluorene]-2-carboxylic acid chemical structure, C16H11BrO2, CAS 41825-94-9
2-Bromospiro[cyclopropane-1,9'-fluorene]-2-carboxylic acid
CAS 41825-94-9C16H11BrO2
Spiro[cyclopropane-2,9'-fluorene]-1-carboxylic acid chemical structure, C16H12O2, CAS 22052-23-9
Spiro[cyclopropane-2,9'-fluorene]-1-carboxylic acid
CAS 22052-23-9C16H12O2
2-Methylspiro[cyclopropane-1,9'-fluorene]-2-carboxylic acid chemical structure, C17H14O2, CAS 41826-00-0
2-Methylspiro[cyclopropane-1,9'-fluorene]-2-carboxylic acid
CAS 41826-00-0C17H14O2
Spiro[cyclopropane-1,9'-fluoren]-2-ylmethanol chemical structure, C16H14O, CAS 27921-39-7
Spiro[cyclopropane-1,9'-fluoren]-2-ylmethanol
CAS 27921-39-7C16H14O
Methyl 2-bromospiro[cyclopropane-1,9'-fluorene]-2-carboxylate chemical structure, C17H13BrO2, CAS 41825-93-8
Methyl 2-bromospiro[cyclopropane-1,9'-fluorene]-2-carboxylate
CAS 41825-93-8C17H13BrO2
Ethyl spiro[cyclopropane-1,9'-fluorene]-2-carboxylate chemical structure, C18H16O2, CAS 21328-27-8
Ethyl spiro[cyclopropane-1,9'-fluorene]-2-carboxylate
CAS 21328-27-8C18H16O2
Spiro[cyclopropane-1,9'-fluorene]-2-carboxamide chemical structure, C16H13NO, CAS 380591-99-1
Spiro[cyclopropane-1,9'-fluorene]-2-carboxamide
CAS 380591-99-1C16H13NO
2-Nitrospiro[cyclopropane-1,9'-fluorene] chemical structure, C15H11NO2, CAS 34163-56-9
2-Nitrospiro[cyclopropane-1,9'-fluorene]
CAS 34163-56-9C15H11NO2
2-Acetoxy-2-cyanospiro[cyclopropane-1,9'-fluorene] chemical structure, C18H13NO2, CAS 87656-19-7
2-Acetoxy-2-cyanospiro[cyclopropane-1,9'-fluorene]
CAS 87656-19-7C18H13NO2
2,3-Dimethyl spiro(cyclopropane-1,9'-(9H)fluorene)-2,3-dicarboxylate chemical structure, C19H16O4, CAS 97043-15-7
2,3-Dimethyl spiro(cyclopropane-1,9'-(9H)fluorene)-2,3-dicarboxylate
CAS 97043-15-7C19H16O4
Spiro[cyclopropane-1,9'-fluorene] chemical structure, C15H12, CAS 167-02-2
Spiro[cyclopropane-1,9'-fluorene]
CAS 167-02-2C15H12
Methyl spiro[cyclopropane-1,9'-fluorene]-2-carboxylate chemical structure, C17H14O2, CAS 27921-38-6
Methyl spiro[cyclopropane-1,9'-fluorene]-2-carboxylate
CAS 27921-38-6C17H14O2
Spiro[cyclopropane-1,9'-fluoren]-2'-amine chemical structure, C15H13N, CAS 81055-96-1
Spiro[cyclopropane-1,9'-fluoren]-2'-amine
CAS 81055-96-1C15H13N
2-Ethenylspiro[cyclopropane-1,9'-fluorene] chemical structure, C17H14, CAS 57393-06-3
2-Ethenylspiro[cyclopropane-1,9'-fluorene]
CAS 57393-06-3C17H14
(2R,3S)-2,3-Dichlorospiro[cyclopropane-1,9'-fluorene] chemical structure, C15H10Cl2, CAS 87319-63-9
(2R,3S)-2,3-Dichlorospiro[cyclopropane-1,9'-fluorene]
CAS 87319-63-9C15H10Cl2
Spiro(cyclopropane-1,9'-(9H)fluorene)-2,3-dicarboxylic acid, diethyl ester, cis- chemical structure, C21H20O4, CAS 41411-72-7
Spiro(cyclopropane-1,9'-(9H)fluorene)-2,3-dicarboxylic acid, diethyl ester, cis-
CAS 41411-72-7C21H20O4
2',7'-Dibromo-2-vinylspiro[cyclopropane-1,9'-fluorene] chemical structure, C17H12Br2, CAS 951884-03-0
2',7'-Dibromo-2-vinylspiro[cyclopropane-1,9'-fluorene]
CAS 951884-03-0C17H12Br2
2',7'-Dibromospiro[cyclopropane-1,9'-fluorene] chemical structure, C15H10Br2, CAS 850784-70-2
2',7'-Dibromospiro[cyclopropane-1,9'-fluorene]
CAS 850784-70-2C15H10Br2
(2S,3S)-2,3-Dimethylspiro[cyclopropane-1,9'-fluorene] chemical structure, C17H16, CAS 34296-54-3
(2S,3S)-2,3-Dimethylspiro[cyclopropane-1,9'-fluorene]
CAS 34296-54-3C17H16
(2S,3S)-Spiro[cyclopropane-1,9'-fluorene]-2,3-dicarboxylic acid chemical structure, C17H12O4, CAS 36336-94-4
(2S,3S)-Spiro[cyclopropane-1,9'-fluorene]-2,3-dicarboxylic acid
CAS 36336-94-4C17H12O4
(2R,3R)-2,3-Dichlorospiro[cyclopropane-1,9'-fluorene] chemical structure, C15H10Cl2, CAS 87319-64-0
(2R,3R)-2,3-Dichlorospiro[cyclopropane-1,9'-fluorene]
CAS 87319-64-0C15H10Cl2
2'-Bromospiro[cyclopropane-1,9'-fluorene] chemical structure, C15H11Br, CAS 863104-50-1
2'-Bromospiro[cyclopropane-1,9'-fluorene]
CAS 863104-50-1C15H11Br