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Murcko scaffold

3,5-Diphenylimidazolidine-2,4-dione scaffold

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
6
With full pages
0
Scaffold SMILES

O=C1NC(c2ccccc2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3,5-Diphenylimidazolidine-2,4-dione page
Murcko scaffold O=C1NC(c2ccccc2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

3,5-Diphenylimidazolidine-2,4-dione chemical structure, C15H12N2O2, CAS 85369-75-1
3,5-Diphenylimidazolidine-2,4-dione
CAS 85369-75-1C15H12N2O2
3-(2-Methylphenyl)-5-phenylimidazolidine-2,4-dione chemical structure, C16H14N2O2, CAS 51027-23-7
3-(2-Methylphenyl)-5-phenylimidazolidine-2,4-dione
CAS 51027-23-7C16H14N2O2
3-(2-Chlorophenyl)-5-phenylimidazolidine-2,4-dione chemical structure, C15H11ClN2O2, CAS 51095-25-1
3-(2-Chlorophenyl)-5-phenylimidazolidine-2,4-dione
CAS 51095-25-1C15H11ClN2O2
4-[3-Ethyl-4-(hydroxymethyl)-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile chemical structure, C20H16F3N3O3, CAS 1215085-94-1
4-[3-Ethyl-4-(hydroxymethyl)-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile
CAS 1215085-94-1C20H16F3N3O3
GLPG0492 (R enantiomer) chemical structure, C19H14F3N3O3, CAS 1215085-93-0
GLPG0492 (R enantiomer)
CAS 1215085-93-0C19H14F3N3O3
Glpg-0492 chemical structure, C19H14F3N3O3, CAS 1215085-92-9
Glpg-0492
CAS 1215085-92-9C19H14F3N3O3