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Murcko scaffold

Ring system with 4 rings and 20 atoms

31 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
31
With full pages
11
Scaffold SMILES

O=C(OC1CC2C1C=CC1CCCC12)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OC1CC2C1C=CC1CCCC12)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

(2R,2aS,4aS,7aS,7bR)-2-((2,4-Dihydroxy-6-methylbenzoyl)oxy)-2,2a,4a,5,6,7,7a,7b-octahydro-2a-hydroxy-6,6,7b-trimethyl-1H-cyclobut(e)indene-3-carboxylic acid chemical structure, C23H28O7, CAS 129251-06-5
(2R,2aS,4aS,7aS,7bR)-2-((2,4-Dihydroxy-6-methylbenzoyl)oxy)-2,2a,4a,5,6,7,7a,7b-octahydro-2a-hydroxy-6,6,7b-trimethyl-1H-cyclobut(e)indene-3-carboxylic acid
CAS 129251-06-5C23H28O7
Armillaritin chemical structure, C23H28O7, CAS 135247-96-0
Armillaritin
CAS 135247-96-0C23H28O7
Armillarivin chemical structure, C23H28O5, CAS 135247-97-1
Armillarivin
CAS 135247-97-1C23H28O5
Armillarin chemical structure, C24H30O6, CAS 83329-14-0
Armillarin
CAS 83329-14-0C24H30O6
Benzoic acid, 2,4-dihydroxy-6-methyl-, (2R,2aS,4aS,7aS,7bR)-3-formyl-2,2a,4a,5,6,7,7a,7b-octahydro-2a-hydroxy-6,6,7b-trimethyl-1H-cyclobut(e)inden-2-yl ester chemical structure, C23H28O6, CAS 82869-08-7
Benzoic acid, 2,4-dihydroxy-6-methyl-, (2R,2aS,4aS,7aS,7bR)-3-formyl-2,2a,4a,5,6,7,7a,7b-octahydro-2a-hydroxy-6,6,7b-trimethyl-1H-cyclobut(e)inden-2-yl ester
CAS 82869-08-7C23H28O6
Armillaripin chemical structure, C24H30O6, CAS 129741-56-6
Armillaripin
CAS 129741-56-6C24H30O6
Melleolide D chemical structure, C24H31ClO8, CAS 101922-80-9
Melleolide D
CAS 101922-80-9C24H31ClO8
4-O-Methylmelleolide chemical structure, C24H30O6, CAS 96627-13-3
4-O-Methylmelleolide
CAS 96627-13-3C24H30O6
5'-O-Methylmelledonal chemical structure, C24H30O8, CAS 112471-07-5
5'-O-Methylmelledonal
CAS 112471-07-5C24H30O8
Melledonal C chemical structure, C24H29ClO8, CAS 117458-35-2
Melledonal C
CAS 117458-35-2C24H29ClO8
Melledonal A chemical structure, C23H28O8, CAS 103847-15-0
Melledonal A
CAS 103847-15-0C23H28O8
Armillarinin chemical structure, C24H29ClO7, CAS 127486-63-9
Armillarinin
CAS 127486-63-9C24H29ClO7
Armillarilin chemical structure, C24H30O7, CAS 127500-59-8
Armillarilin
CAS 127500-59-8C24H30O7
Melleolide K chemical structure, C23H27ClO6, CAS 264229-80-3
Melleolide K
CAS 264229-80-3C23H27ClO6
Melleolide L chemical structure, C23H27ClO7, CAS 298702-67-7
Melleolide L
CAS 298702-67-7C23H27ClO7
Melleolide M chemical structure, C23H29ClO7, CAS 264229-82-5
Melleolide M
CAS 264229-82-5C23H29ClO7
Melleolide F chemical structure, C23H30O6, CAS 117258-74-9
Melleolide F
CAS 117258-74-9C23H30O6
[(2R,2aS,4aS,7R,7aS,7bR)-2a,7-Dihydroxy-3-(hydroxymethyl)-6,6,7b-trimethyl-1,2,4a,5,7,7a-hexahydrocyclobuta[e]inden-2-yl] 2-hydroxy-4-methoxy-6-methylbenzoate chemical structure, C24H32O7, CAS 101901-55-7
[(2R,2aS,4aS,7R,7aS,7bR)-2a,7-Dihydroxy-3-(hydroxymethyl)-6,6,7b-trimethyl-1,2,4a,5,7,7a-hexahydrocyclobuta[e]inden-2-yl] 2-hydroxy-4-methoxy-6-methylbenzoate
CAS 101901-55-7C24H32O7
Melleolide C chemical structure, C24H32O8, CAS 101901-56-8
Melleolide C
CAS 101901-56-8C24H32O8
[(2R,2aS,4aS,7R,7aS,7bR)-2a,7-Dihydroxy-3-(hydroxymethyl)-6,6,7b-trimethyl-1,2,4a,5,7,7a-hexahydrocyclobuta[e]inden-2-yl] 2,4-dihydroxy-6-methylbenzoate chemical structure, C23H30O7, CAS 117258-73-8
[(2R,2aS,4aS,7R,7aS,7bR)-2a,7-Dihydroxy-3-(hydroxymethyl)-6,6,7b-trimethyl-1,2,4a,5,7,7a-hexahydrocyclobuta[e]inden-2-yl] 2,4-dihydroxy-6-methylbenzoate
CAS 117258-73-8C23H30O7
[(2R,2aS,4aS,6R,7aS,7bR)-2a-Hydroxy-3,6-bis(hydroxymethyl)-6,7b-dimethyl-1,2,4a,5,7,7a-hexahydrocyclobuta[e]inden-2-yl] 2-hydroxy-4-methoxy-6-methylbenzoate chemical structure, C24H32O7, CAS 117258-75-0
[(2R,2aS,4aS,6R,7aS,7bR)-2a-Hydroxy-3,6-bis(hydroxymethyl)-6,7b-dimethyl-1,2,4a,5,7,7a-hexahydrocyclobuta[e]inden-2-yl] 2-hydroxy-4-methoxy-6-methylbenzoate
CAS 117258-75-0C24H32O7
Melleolide H chemical structure, C24H30O7, CAS 117240-47-8
Melleolide H
CAS 117240-47-8C24H30O7
4-O-Methylarmillaridin chemical structure, C25H31ClO6, CAS 126006-70-0
4-O-Methylarmillaridin
CAS 126006-70-0C25H31ClO6
Melledonol chemical structure, C23H30O8, CAS 103847-14-9
Melledonol
CAS 103847-14-9C23H30O8