Murcko scaffold
Ring system with 4 rings and 25 atoms
33 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 33
- With full pages
- 8
Scaffold SMILES
c1ccc2c(c1)CCC(CCNCCC1CCc3ccccc3O1)O2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 33 of 33 chemicals
Nebivolol
CAS 118457-14-0C22H25F2NO4
Alpha,alpha'-(iminobis(methylene))bis(3,4-dihydro-2H-1-benzopyran-2-methanol)
CAS 125591-32-4C22H27NO4
Dexnebivolol
CAS 118457-15-1C22H25F2NO4
(S,S,S,S)-Nebivolol
CAS 119365-28-5C22H25F2NO4
(-)-Nebivolol
CAS 118457-16-2C22H25F2NO4
2,2'-Azanediylbis(1-(6-fluorochroman-2-yl)ethanol) hydrochloride
CAS 169293-50-9C22H26ClF2NO4
2H-1-Benzopyran-2-methanol, alpha,alpha'-(iminobis(methylene))bis(6-fluoro-3,4-dihydro-, hydrochloride (1:1), (alphaR,alpha'R,2R,2'S)-rel-
CAS 152520-56-4C22H26ClF2NO4
(S,R,R,S)-Nebivolol
CAS 119365-23-0C22H25F2NO4
Nebivolol hydrochloride
CAS 213132-06-0C22H26ClF2NO4
Nebivolol EP impurity D
CAS 119365-26-3C22H25F2NO4
![(S)-1-[(S)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[(R)-2-[(S)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethylamino]ethanol chemical structure, C22H25F2NO4, CAS 119365-25-2](/s/KOHIRBRYDXPAMZ-UDKICSLYSA-N.svg)
(S)-1-[(S)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[(R)-2-[(S)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethylamino]ethanol
CAS 119365-25-2C22H25F2NO4
(R,R,S,S)-Nebivolol
CAS 119365-27-4C22H25F2NO4
(R,R,R,R)-Nebivolol
CAS 119365-29-6C22H25F2NO4
![(AlphaR,alpha'S,2S,2'R)-alpha,alpha'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] chemical structure, C22H25F2NO4, CAS 119365-24-1](/s/KOHIRBRYDXPAMZ-MTIDIVMFSA-N.svg)
(AlphaR,alpha'S,2S,2'R)-alpha,alpha'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]
CAS 119365-24-1C22H25F2NO4
rac Nebivolol-d8
CAS 1219166-00-3C22H25F2NO4
rac Nebivolol-d4 (Major)
CAS 1219407-55-2C22H25F2NO4
(R,S,S,R)-Nebivolol
CAS 119365-30-9C22H25F2NO4
Desfluoro nebivolol
CAS 129101-34-4C22H26FNO4
4-tert-Butyldimethylsilyloxy Nebivolol
CAS 1287115-86-9C28H39F2NO5Si
4-Hydroxy nebivolol
CAS 178383-76-1C22H28ClF2NO6
![2H-1-Benzopyran-2-methanol, 6-fluoro-alpha-[[[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino]methyl]-3,4-dihydro-4-hydroxy- chemical structure, C22H25F2NO5](/s/SHOYFMMYOPYJML-UHFFFAOYSA-N.svg)
2H-1-Benzopyran-2-methanol, 6-fluoro-alpha-[[[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino]methyl]-3,4-dihydro-4-hydroxy-
C22H25F2NO5
N,N-Bis(2-(6-fluorochroman-2-yl)-2-hydroxyethyl)nitrous amide
CAS 1391051-68-5C22H24F2N2O5
Nebivolol impurity 33(SS,SR)
CAS 129101-35-5C22H26FNO4
4-Hydroxy nebivolol hydrochloride
CAS 2717115-85-8C22H26ClF2NO5
- (1S,1'S)-2,2'-Azanediylbis(1-((R)-6-fluorochroman-2-yl)ethan-1-ol) hydrochloride920275-23-6C22H26ClF2NO4
- (1R)-1-[(2S)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2R)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol, hydrochloride920275-19-0C22H26ClF2NO4
- (Rac)-Nebivolol-d4 (hydrochloride)2701283-32-9C22H26ClF2NO4
- Nebivolol impurity 52(RR,RS)1696472-14-6C22H26FNO4
- rel-(S,R,S,S)-Nebivolol Hydrochloride1338823-20-3C22H26ClF2NO4
- Nebivolol-5,5',7,7',8,8'-d62824330-68-7C22H25F2NO4
- Nebivolol impurity 61696430-24-6C22H27ClFNO4
- Desfluoro nebivolol hydrochloride R,R,R,S diastereomer1696430-23-5C22H27ClFNO4
- Nebivolol EP impurity A1696472-15-7C22H26FNO4
Related scaffolds
Same ring framework with different atoms or bond orders
