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Murcko scaffold

Ring system with 3 rings and 14 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
7
With full pages
2
Scaffold SMILES

O=c1ncccn1C1OC2COC1C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ncccn1C1OC2COC1C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

4-Amino-1-[(1R,3R,4S,7R)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1,2-dihydropyrimidin-2-one chemical structure, C9H11N3O4, CAS 32830-01-6
4-Amino-1-[(1R,3R,4S,7R)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1,2-dihydropyrimidin-2-one
CAS 32830-01-6C9H11N3O4
4-Amino-1-[(1s,3r,4r,7s)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]hept-3-Yl]-5-methylpyrimidin-2(1H)-one chemical structure, C11H15N3O5, CAS 847650-87-7
4-Amino-1-[(1s,3r,4r,7s)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]hept-3-Yl]-5-methylpyrimidin-2(1H)-one
CAS 847650-87-7C11H15N3O5
2'-O,4'-C-Methylenecytidine chemical structure, C10H13N3O5, CAS 206055-69-8
2'-O,4'-C-Methylenecytidine
CAS 206055-69-8C10H13N3O5
Lna-C-TP chemical structure, C10H16N3O14P3, CAS 847650-98-0
Lna-C-TP
CAS 847650-98-0C10H16N3O14P3
2'-O,4'-C-((1S)-ethane-1,1-diyl)beta-D-ribose 5-methyl cytidine chemical structure, C12H17N3O5, CAS 1197033-37-6
2'-O,4'-C-((1S)-ethane-1,1-diyl)beta-D-ribose 5-methyl cytidine
CAS 1197033-37-6C12H17N3O5
2'-O,4'-C-((1S)-ethane-1,1-diyl)beta-D-ribose cytidine chemical structure, C11H15N3O5, CAS 1197033-36-5
2'-O,4'-C-((1S)-ethane-1,1-diyl)beta-D-ribose cytidine
CAS 1197033-36-5C11H15N3O5
tert-Butyl N-{1-[(1R,3R,4S,7R)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}carbamate chemical structure, C14H19N3O6, CAS 2413846-46-3
tert-Butyl N-{1-[(1R,3R,4S,7R)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}carbamate
CAS 2413846-46-3C14H19N3O6