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Murcko scaffold

Ring system with 3 rings and 15 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
17
With full pages
2
Scaffold SMILES

O=c1ccn(C2OC3COC2C3)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(C2OC3COC2C3)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

1-(2,5-Anhydropentofuranosyl)-4-hydroxypyrimidin-2(1H)-one chemical structure, C9H10N2O5, CAS 3257-75-8
1-(2,5-Anhydropentofuranosyl)-4-hydroxypyrimidin-2(1H)-one
CAS 3257-75-8C9H10N2O5
[3-(2,4-Dioxopyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl] methanesulfonate chemical structure, C10H12N2O7S, CAS 3257-80-5
[3-(2,4-Dioxopyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl] methanesulfonate
CAS 3257-80-5C10H12N2O7S
1-[(1R,4S,6R,7S)-7-Azido-4-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-6-yl]-5-methyl-pyrimidine-2,4-dione chemical structure, C11H13N5O5, CAS 247025-17-8
1-[(1R,4S,6R,7S)-7-Azido-4-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-6-yl]-5-methyl-pyrimidine-2,4-dione
CAS 247025-17-8C11H13N5O5
1-((1S,3R,4R,7S)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-methylpyrimidine-2,4(1H,3H)-dione chemical structure, C11H14N2O6, CAS 206055-67-6
1-((1S,3R,4R,7S)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
CAS 206055-67-6C11H14N2O6
1-((1S,3R,4R,7S)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C10H12N2O6, CAS 200435-92-3
1-((1S,3R,4R,7S)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidine-2,4(1H,3H)-dione
CAS 200435-92-3C10H12N2O6
2'-O,4'-C-((1S)-ethane-1,1-diyl)beta-D-ribose 5-methyl uridine chemical structure, C12H16N2O6, CAS 1197032-96-4
2'-O,4'-C-((1S)-ethane-1,1-diyl)beta-D-ribose 5-methyl uridine
CAS 1197032-96-4C12H16N2O6
1-((1S,3R,4R,7R)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C10H12N2O6, CAS 1328937-93-4
1-((1S,3R,4R,7R)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidine-2,4(1H,3H)-dione
CAS 1328937-93-4C10H12N2O6
Lna-U-TP chemical structure, C10H15N2O15P3, CAS 1258616-54-4
Lna-U-TP
CAS 1258616-54-4C10H15N2O15P3
5-Bromo-1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidine-2,4-dione chemical structure, C10H11BrN2O6, CAS 320590-22-5
5-Bromo-1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidine-2,4-dione
CAS 320590-22-5C10H11BrN2O6
2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-3-azido-3-deoxy-4-C-(hydroxymethyl)-I(2)-D-arabinofuranosyl]-5-methyl- chemical structure, C11H13N5O5, CAS 319919-16-9
2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-3-azido-3-deoxy-4-C-(hydroxymethyl)-I(2)-D-arabinofuranosyl]-5-methyl-
CAS 319919-16-9C11H13N5O5
2'-O,4'-C-((1S)-ethane-1,1-diyl)beta-D-ribose uridine chemical structure, C11H14N2O6, CAS 945628-49-9
2'-O,4'-C-((1S)-ethane-1,1-diyl)beta-D-ribose uridine
CAS 945628-49-9C11H14N2O6
1-[(1R,4R,7R)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C10H12N2O6
1-[(1R,4R,7R)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
C10H12N2O6
1-((1S,3R,7S)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C10H12N2O6
1-((1S,3R,7S)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidine-2,4(1H,3H)-dione
C10H12N2O6
1-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C10H12N2O6
1-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-2,4(1H,3H)-pyrimidinedione
C10H12N2O6
1-[(1S,3R,4R,7S)-1-(Aminomethyl)-7-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidine-2,4-dione chemical structure, C17H29N3O5Si, CAS 2920197-59-5
1-[(1S,3R,4R,7S)-1-(Aminomethyl)-7-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidine-2,4-dione
CAS 2920197-59-5C17H29N3O5Si
1-[(1S,3R,4R,7S)-1-(Azidomethyl)-7-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidine-2,4-dione chemical structure, C17H27N5O5Si, CAS 2920179-19-5
1-[(1S,3R,4R,7S)-1-(Azidomethyl)-7-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidine-2,4-dione
CAS 2920179-19-5C17H27N5O5Si
5'-Azido-5'-deoxy-2'-O,4'-C-methyleneuridine chemical structure, C10H11N5O5, CAS 2305415-75-0
5'-Azido-5'-deoxy-2'-O,4'-C-methyleneuridine
CAS 2305415-75-0C10H11N5O5