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Murcko scaffold

2-Phenyl-2,5-diazabicyclo[2.2.1]heptane scaffold

35 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
35
With full pages
4
Scaffold SMILES

c1ccc(N2CC3CC2CN3)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-2,5-diazabicyclo[2.2.1]heptane page
Murcko scaffold c1ccc(N2CC3CC2CN3)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

2-(4-Fluorophenyl)-2,5-diazabicyclo[2.2.1]heptane chemical structure, C11H13FN2, CAS 198988-90-8
2-(4-Fluorophenyl)-2,5-diazabicyclo[2.2.1]heptane
CAS 198988-90-8C11H13FN2
2-(4-Chlorophenyl)-2,5-diazabicyclo[2.2.1]heptane chemical structure, C11H13ClN2, CAS 198988-88-4
2-(4-Chlorophenyl)-2,5-diazabicyclo[2.2.1]heptane
CAS 198988-88-4C11H13ClN2
2-(3-Fluorophenyl)-2,5-diazabicyclo[2.2.1]heptane chemical structure, C11H13FN2, CAS 1029712-59-1
2-(3-Fluorophenyl)-2,5-diazabicyclo[2.2.1]heptane
CAS 1029712-59-1C11H13FN2
2-(4-Methylphenyl)-2,5-diazabicyclo[2.2.1]heptane chemical structure, C12H16N2, CAS 198988-86-2
2-(4-Methylphenyl)-2,5-diazabicyclo[2.2.1]heptane
CAS 198988-86-2C12H16N2
(1S,4S)-()-2-(4-Chlorophenyl)-2,5-diazabicyclo[2.2.1]heptane hydrobromide chemical structure, C11H14BrClN2
(1S,4S)-()-2-(4-Chlorophenyl)-2,5-diazabicyclo[2.2.1]heptane hydrobromide
C11H14BrClN2
(1S,4S)-(-)-2-(4-Fluorophenyl)-2,5-diazabicyclo[2.2.1]heptane hydrobromide chemical structure, C11H14BrFN2, CAS 308103-49-3
(1S,4S)-(-)-2-(4-Fluorophenyl)-2,5-diazabicyclo[2.2.1]heptane hydrobromide
CAS 308103-49-3C11H14BrFN2
(1S,4S)-(-)-2-(3-Fluorophenyl)-2,5-diazabicyclo[2.2.1]heptane hydrobromide chemical structure, C11H14BrFN2, CAS 294177-35-8
(1S,4S)-(-)-2-(3-Fluorophenyl)-2,5-diazabicyclo[2.2.1]heptane hydrobromide
CAS 294177-35-8C11H14BrFN2
2-(2-Methoxyphenyl)-2,5-diazabicyclo[2.2.1]heptane chemical structure, C12H16N2O, CAS 877066-89-2
2-(2-Methoxyphenyl)-2,5-diazabicyclo[2.2.1]heptane
CAS 877066-89-2C12H16N2O
(1S,4S)-2-Phenyl-2,5-diazabicyclo[2.2.1]heptane chemical structure, C11H14N2, CAS 294177-33-6
(1S,4S)-2-Phenyl-2,5-diazabicyclo[2.2.1]heptane
CAS 294177-33-6C11H14N2
2,5-Diazabicyclo[2.2.1]heptane,2-(4-chlorophenyl)- chemical structure, C11H13ClN2
2,5-Diazabicyclo[2.2.1]heptane,2-(4-chlorophenyl)-
C11H13ClN2
2-Phenyl-2,5-diazabicyclo[2.2.1]heptane chemical structure, C11H14N2, CAS 198988-84-0
2-Phenyl-2,5-diazabicyclo[2.2.1]heptane
CAS 198988-84-0C11H14N2
2-Methyl-5-(4-nitro-phenyl)-2,5-diaza-bicyclo[2.2.1]heptane chemical structure, C12H15N3O2, CAS 943751-16-4
2-Methyl-5-(4-nitro-phenyl)-2,5-diaza-bicyclo[2.2.1]heptane
CAS 943751-16-4C12H15N3O2
2-(3-Chloropropyl)-5-phenyl-2,5-diazabicyclo[2.2.1]heptane chemical structure, C14H19ClN2, CAS 198988-91-9
2-(3-Chloropropyl)-5-phenyl-2,5-diazabicyclo[2.2.1]heptane
CAS 198988-91-9C14H19ClN2
(1S,4S)-(-)-2-(4-Chlorophenyl)-2,5-diazabicyclo[2.2.1]heptane hydrobromide chemical structure, C11H14BrClN2, CAS 308103-51-7
(1S,4S)-(-)-2-(4-Chlorophenyl)-2,5-diazabicyclo[2.2.1]heptane hydrobromide
CAS 308103-51-7C11H14BrClN2
2-(4-Nitrophenyl)-2,5-diazabicyclo[2.2.1]heptane chemical structure, C11H13N3O2, CAS 1093094-99-5
2-(4-Nitrophenyl)-2,5-diazabicyclo[2.2.1]heptane
CAS 1093094-99-5C11H13N3O2
4-[(1S,4S)-2,5-Diazabicyclo[2.2.1]heptan-2-yl]aniline chemical structure, C11H15N3, CAS 370885-26-0
4-[(1S,4S)-2,5-Diazabicyclo[2.2.1]heptan-2-yl]aniline
CAS 370885-26-0C11H15N3
tert-Butyl 5-(4-acetylphenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate chemical structure, C18H24N2O3, CAS 1186334-97-3
tert-Butyl 5-(4-acetylphenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
CAS 1186334-97-3C18H24N2O3
(1S,4S)-2-(2-Methylphenyl)-2,5-diazabicyclo[2.2.1]heptane chemical structure, C12H16N2, CAS 294177-36-9
(1S,4S)-2-(2-Methylphenyl)-2,5-diazabicyclo[2.2.1]heptane
CAS 294177-36-9C12H16N2
4-((1S,4S)-5-Isopropyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-phenylamine chemical structure, C14H21N3, CAS 1195064-72-2
4-((1S,4S)-5-Isopropyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-phenylamine
CAS 1195064-72-2C14H21N3
(1S,4S)-2-(4-Nitrophenyl)-5-(propan-2-yl)-2,5-diazabicyclo[2.2.1]heptane chemical structure, C14H19N3O2, CAS 1195064-77-7
(1S,4S)-2-(4-Nitrophenyl)-5-(propan-2-yl)-2,5-diazabicyclo[2.2.1]heptane
CAS 1195064-77-7C14H19N3O2
5-(4-Aminophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester chemical structure, C16H23N3O2, CAS 643087-74-5
5-(4-Aminophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
CAS 643087-74-5C16H23N3O2
5-(4-Nitrophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester chemical structure, C16H21N3O4, CAS 877212-94-7
5-(4-Nitrophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
CAS 877212-94-7C16H21N3O4
4-(5-Methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)aniline chemical structure, C12H17N3, CAS 943751-17-5
4-(5-Methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)aniline
CAS 943751-17-5C12H17N3
(1S,4S)-2-[4-(Methanesulfonyl)phenyl]-2,5-diazabicyclo[2.2.1]heptane chemical structure, C12H16N2O2S, CAS 918884-38-5
(1S,4S)-2-[4-(Methanesulfonyl)phenyl]-2,5-diazabicyclo[2.2.1]heptane
CAS 918884-38-5C12H16N2O2S