Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 21 atoms

15 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 21
Chemicals: 15
With full pages: 3

Scaffold SMILES

O=C(Nc1ccccc1)c1cc2cc3c(nc2s1)CCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1ccccc1)c1cc2cc3c(nc2s1)CCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

3-Amino-N-(2,3-dimethylphenyl)-6,7-dihydro-5H-cyclopenta[B]thieno[3,2-E]pyridine-2-carboxamide chemical structure, C19H19N3OS, CAS 309741-89-7

3-Amino-N-(2,3-dimethylphenyl)-6,7-dihydro-5H-cyclopenta[B]thieno[3,2-E]pyridine-2-carboxamide

CAS 309741-89-7C₁₉H₁₉N₃OS

RefChem:381457 chemical structure, C17H15N3OS, CAS 6244-21-9

CAS 6244-21-9C₁₇H₁₅N₃OS

3-Amino-N-(2-fluorophenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C17H14FN3OS, CAS 354793-61-6

3-Amino-N-(2-fluorophenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 354793-61-6C₁₇H₁₄FN₃OS

3-Amino-N-(4-methylphenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C18H17N3OS, CAS 354793-59-2

3-Amino-N-(4-methylphenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 354793-59-2C₁₈H₁₇N₃OS

3-Amino-N-(4-chlorophenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C17H14ClN3OS, CAS 428444-64-8

3-Amino-N-(4-chlorophenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 428444-64-8C₁₇H₁₄ClN₃OS

3-Amino-N-(4-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C18H17N3O2S, CAS 340813-04-9

3-Amino-N-(4-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 340813-04-9C₁₈H₁₇N₃O₂S

3-Amino-N-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C18H14F3N3OS, CAS 445384-37-2

3-Amino-N-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 445384-37-2C₁₈H₁₄F₃N₃OS

3-Amino-N-(4-bromo-2-methylphenyl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C19H15BrF3N3OS, CAS 626228-80-6

3-Amino-N-(4-bromo-2-methylphenyl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 626228-80-6C₁₉H₁₅BrF₃N₃OS

3-Amino-N-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C18H12ClF4N3OS, CAS 626227-22-3

3-Amino-N-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 626227-22-3C₁₈H₁₂ClF₄N₃OS

3-Amino-N-[4-(methylsulfanyl)phenyl]-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C18H17N3OS2, CAS 665000-91-9

3-Amino-N-[4-(methylsulfanyl)phenyl]-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 665000-91-9C₁₈H₁₇N₃OS₂

DC_AC50 chemical structure, C17H12BrF2N3OS, CAS 497061-48-0

CAS 497061-48-0C₁₇H₁₂BrF₂N₃OS

$6-Amino-N-(3-cyanophenyl)-8-(trifluoromethyl)-4-thia-2-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,5,7-tetraene-5-carboxamide chemical structure, C19H13F3N4OS, CAS 626222-18-2$

6-Amino-N-(3-cyanophenyl)-8-(trifluoromethyl)-4-thia-2-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,5,7-tetraene-5-carboxamide

CAS 626222-18-2C₁₉H₁₃F₃N₄OS

3-Amino-N-(2,6-dichlorophenyl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C18H12Cl2F3N3OS, CAS 626227-29-0

3-Amino-N-(2,6-dichlorophenyl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 626227-29-0C₁₈H₁₂Cl₂F₃N₃OS

3-Amino-N-(2-chloro-5-(trifluoromethyl)phenyl)-6,7-dihydro-5H-cyclopenta(B)thieno(3,2-E)pyridine-2-carboxamide chemical structure, C18H13ClF3N3OS, CAS 400864-40-6

3-Amino-N-(2-chloro-5-(trifluoromethyl)phenyl)-6,7-dihydro-5H-cyclopenta(B)thieno(3,2-E)pyridine-2-carboxamide

CAS 400864-40-6C₁₈H₁₃ClF₃N₃OS

3-Amino-N-(4-nitrophenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C17H14N4O3S, CAS 361198-39-2

3-Amino-N-(4-nitrophenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 361198-39-2C₁₇H₁₄N₄O₃S