Murcko scaffold
Ring system with 5 rings and 29 atoms
10 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 29
- Chemicals
- 10
- With full pages
- 2
Scaffold SMILES
c1ccc(Oc2cncnc2N2CC3(CCN(CC4CCCCC4)CC3)C2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 10 of 10 chemicals
Revumenib
CAS 2169919-21-3C32H47FN6O4S
![5-Fluoro-2-({4-[7-({trans-4-[(methylsulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N,N-di(propan-2-yl)benzamide chemical structure, C32H47FN6O4S, CAS 2169916-18-9](/s/ADHHOUXZPBYYSU-UHFFFAOYSA-N.svg)
5-Fluoro-2-({4-[7-({trans-4-[(methylsulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N,N-di(propan-2-yl)benzamide
CAS 2169916-18-9C32H47FN6O4S
VTP50469 (mesylate)
CAS 2169919-27-9C34H55FN6O10S3
(1s,4s)-Menin-MLL inhibitor-23
CAS 2169919-19-9C36H53FN6O4
SNDX-5613 sesquifumarate
CAS 2169919-22-4C76H106F2N12O20S2
VTP50469 mesylate
C33H51FN6O7S2
VTP50469 fumarate
CAS 2169919-29-1C76H106F2N12O20S2
VTP50469 (fumarate)
C37H55FN6O8S
Revumenib citrate
CAS 2761046-45-9C38H57FN6O12S
![5-Fluoro-N,N-diisopropyl-2-((4-(7-((trans-4-(methylsulfonamido)cyclohexyl)methyl)-2,7-diazaspiro[3.5]nonan-2-yl)pyrimidin-5-yl)oxy)benzamide fumarate chemical structure, C36H51FN6O8S](/s/QQPRVUWGVHQBCR-WLHGVMLRSA-N.svg)
5-Fluoro-N,N-diisopropyl-2-((4-(7-((trans-4-(methylsulfonamido)cyclohexyl)methyl)-2,7-diazaspiro[3.5]nonan-2-yl)pyrimidin-5-yl)oxy)benzamide fumarate
C36H51FN6O8S