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Murcko scaffold

Ring system with 3 rings and 15 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
11
With full pages
4
Scaffold SMILES

c1ccc(C2=NNC3(CCCC3)O2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2=NNC3(CCCC3)O2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

1-(3-Phenyl-4-oxa-1,2-diaza-spiro[4.4]non-2-en-1-yl)-ethanone chemical structure, C14H16N2O2, CAS 352454-16-1
1-(3-Phenyl-4-oxa-1,2-diaza-spiro[4.4]non-2-en-1-yl)-ethanone
CAS 352454-16-1C14H16N2O2
1-[3-(3-Iodo-phenyl)-4-oxa-1,2-diaza-spiro[4.4]non-2-en-1-yl]-ethanone chemical structure, C14H15IN2O2, CAS 332169-51-4
1-[3-(3-Iodo-phenyl)-4-oxa-1,2-diaza-spiro[4.4]non-2-en-1-yl]-ethanone
CAS 332169-51-4C14H15IN2O2
1-[3-(2,4-Dichlorophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl]ethanone chemical structure, C14H14Cl2N2O2, CAS 392734-20-2
1-[3-(2,4-Dichlorophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl]ethanone
CAS 392734-20-2C14H14Cl2N2O2
1-[3-(3-Bromophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl]ethanone chemical structure, C14H15BrN2O2, CAS 299201-01-7
1-[3-(3-Bromophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl]ethanone
CAS 299201-01-7C14H15BrN2O2
1-(3-(3-Methoxyphenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl)ethanone chemical structure, C15H18N2O3, CAS 331713-44-1
1-(3-(3-Methoxyphenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl)ethanone
CAS 331713-44-1C15H18N2O3
1-Acetyl-3-(4-fluorophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-ene chemical structure, C14H15FN2O2, CAS 332169-49-0
1-Acetyl-3-(4-fluorophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-ene
CAS 332169-49-0C14H15FN2O2
1-[3-(4-Chlorophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl]ethanone chemical structure, C14H15ClN2O2, CAS 489416-41-3
1-[3-(4-Chlorophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl]ethanone
CAS 489416-41-3C14H15ClN2O2
1-[3-(3-Methylphenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl]ethanone chemical structure, C15H18N2O2, CAS 339234-27-4
1-[3-(3-Methylphenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl]ethanone
CAS 339234-27-4C15H18N2O2
1-Acetyl-3-(3-chloro-4-methylphenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-ene chemical structure, C15H17ClN2O2, CAS 663945-41-3
1-Acetyl-3-(3-chloro-4-methylphenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-ene
CAS 663945-41-3C15H17ClN2O2
1-[3-(4-Bromophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl]ethanone chemical structure, C14H15BrN2O2, CAS 299199-73-8
1-[3-(4-Bromophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-en-1-yl]ethanone
CAS 299199-73-8C14H15BrN2O2
1-Acetyl-3-(4-iodophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-ene chemical structure, C14H15IN2O2, CAS 327991-05-9
1-Acetyl-3-(4-iodophenyl)-4-oxa-1,2-diazaspiro[4.4]non-2-ene
CAS 327991-05-9C14H15IN2O2