CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 28 atoms

230 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
28
Chemicals
230
With full pages
12
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 230 chemicals

1-(9H-Fluoren-9-ylmethyl) (2S,4S)-4-phenyl-1,2-pyrrolidinedicarboxylate chemical structure, C26H23NO4, CAS 269078-71-9
1-(9H-Fluoren-9-ylmethyl) (2S,4S)-4-phenyl-1,2-pyrrolidinedicarboxylate
CAS 269078-71-9C26H23NO4
(2s,4r)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-2-carboxylic acid chemical structure, C26H23NO4, CAS 1093651-96-7
(2s,4r)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-2-carboxylic acid
CAS 1093651-96-7C26H23NO4
Fmoc-cis-DL-3-phenyl-Pro-OH chemical structure, C26H23NO4, CAS 181824-45-3
Fmoc-cis-DL-3-phenyl-Pro-OH
CAS 181824-45-3C26H23NO4
1-(9H-Fluoren-9-ylmethoxycarbonyl)-3-phenylpyrrolidine-2-carboxylic acid chemical structure, C26H23NO4, CAS 1822484-24-1
1-(9H-Fluoren-9-ylmethoxycarbonyl)-3-phenylpyrrolidine-2-carboxylic acid
CAS 1822484-24-1C26H23NO4
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-3-carboxylic acid chemical structure, C26H23NO4, CAS 955315-36-3
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-3-carboxylic acid
CAS 955315-36-3C26H23NO4
rac-(2R,3S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-phenylpyrrolidine-2-carboxylic acid chemical structure, C26H23NO4, CAS 1579983-87-1
rac-(2R,3S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-phenylpyrrolidine-2-carboxylic acid
CAS 1579983-87-1C26H23NO4
1,2-Pyrrolidinedicarboxylic acid, 3-phenyl-, 1-(9H-fluoren-9-ylmethyl) ester, cis-(9CI) chemical structure, C26H23NO4, CAS 1260886-22-3
1,2-Pyrrolidinedicarboxylic acid, 3-phenyl-, 1-(9H-fluoren-9-ylmethyl) ester, cis-(9CI)
CAS 1260886-22-3C26H23NO4
rac-(3R,4S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-phenylpyrrolidine-3-carboxylic acid chemical structure, C26H23NO4, CAS 1361197-86-5
rac-(3R,4S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-phenylpyrrolidine-3-carboxylic acid
CAS 1361197-86-5C26H23NO4
(2R,3S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-phenylpyrrolidine-2-carboxylic acid chemical structure, C26H23NO4, CAS 2381715-72-4
(2R,3S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-phenylpyrrolidine-2-carboxylic acid
CAS 2381715-72-4C26H23NO4
(3R,4R)-1-(9H-Fluoren-9-ylmethoxycarbonyl)-4-phenylpyrrolidine-3-carboxylic acid chemical structure, C26H23NO4, CAS 2138183-78-3
(3R,4R)-1-(9H-Fluoren-9-ylmethoxycarbonyl)-4-phenylpyrrolidine-3-carboxylic acid
CAS 2138183-78-3C26H23NO4
(3S,4R)-1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-phenylpyrrolidine-3-carboxylic acid chemical structure, C26H23NO4, CAS 2137078-59-0
(3S,4R)-1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-phenylpyrrolidine-3-carboxylic acid
CAS 2137078-59-0C26H23NO4
(3S,4S)-1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-phenylpyrrolidine-3-carboxylic acid chemical structure, C26H23NO4, CAS 2171290-72-3
(3S,4S)-1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-phenylpyrrolidine-3-carboxylic acid
CAS 2171290-72-3C26H23NO4
(2R,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-2-carboxylic acid chemical structure, C26H23NO4, CAS 1449693-85-9
(2R,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-2-carboxylic acid
CAS 1449693-85-9C26H23NO4
rac-(3R,4S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-(4-methylphenyl)pyrrolidine-3-carboxylic acid chemical structure, C27H25NO4, CAS 1279037-25-0
rac-(3R,4S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-(4-methylphenyl)pyrrolidine-3-carboxylic acid
CAS 1279037-25-0C27H25NO4
rac-(3R,4S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-(4-fluorophenyl)pyrrolidine-3-carboxylic acid chemical structure, C26H22FNO4, CAS 2127056-86-2
rac-(3R,4S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-(4-fluorophenyl)pyrrolidine-3-carboxylic acid
CAS 2127056-86-2C26H22FNO4
(3S,4R)-1-(9H-Fluoren-9-ylmethoxycarbonyl)-4-(3-methoxyphenyl)pyrrolidine-3-carboxylic acid chemical structure, C27H25NO5, CAS 2125660-58-2
(3S,4R)-1-(9H-Fluoren-9-ylmethoxycarbonyl)-4-(3-methoxyphenyl)pyrrolidine-3-carboxylic acid
CAS 2125660-58-2C27H25NO5
(3S,4R)-4-(2,4-Difluorophenyl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid chemical structure, C26H21F2NO4, CAS 2155840-33-6
(3S,4R)-4-(2,4-Difluorophenyl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid
CAS 2155840-33-6C26H21F2NO4
(3S,4R)-4-(4-Bromophenyl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid chemical structure, C26H22BrNO4, CAS 2137061-65-3
(3S,4R)-4-(4-Bromophenyl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid
CAS 2137061-65-3C26H22BrNO4
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-phenylpyrrolidine-3-carboxylic acid chemical structure, C26H23NO4, CAS 2138371-99-8
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-phenylpyrrolidine-3-carboxylic acid
CAS 2138371-99-8C26H23NO4
4-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-methylpyrrolidin-3-yl)benzoic acid chemical structure, C27H25NO4, CAS 2137875-81-9
4-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-methylpyrrolidin-3-yl)benzoic acid
CAS 2137875-81-9C27H25NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-fluoro-4-phenylpyrrolidine-3-carboxylic acid chemical structure, C26H22FNO4, CAS 2137774-86-6
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-fluoro-4-phenylpyrrolidine-3-carboxylic acid
CAS 2137774-86-6C26H22FNO4
(3R,4S)-1-(9H-Fluoren-9-ylmethoxycarbonyl)-4-phenyl-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid chemical structure, C27H22F3NO4, CAS 2137777-76-3
(3R,4S)-1-(9H-Fluoren-9-ylmethoxycarbonyl)-4-phenyl-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid
CAS 2137777-76-3C27H22F3NO4
rac-(3R,4S)-4-(4-Chlorophenyl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid chemical structure, C26H22ClNO4, CAS 2127056-95-3
rac-(3R,4S)-4-(4-Chlorophenyl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid
CAS 2127056-95-3C26H22ClNO4
rac-(3R,4S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid chemical structure, C27H25NO5, CAS 2127012-04-6
rac-(3R,4S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid
CAS 2127012-04-6C27H25NO5