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Murcko scaffold

Ring system with 5 rings and 28 atoms

13 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
28
Chemicals
13
With full pages
1
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(c2ccccn2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(c2ccccn2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

rac-(3R,4R)-4-(5-Bromopyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid chemical structure, C25H21BrN2O4, CAS 2287237-39-0
rac-(3R,4R)-4-(5-Bromopyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid
CAS 2287237-39-0C25H21BrN2O4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(6-methoxypyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C26H24N2O5, CAS 2171835-89-3
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(6-methoxypyridin-2-yl)pyrrolidine-3-carboxylic acid
CAS 2171835-89-3C26H24N2O5
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(5-methylpyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C26H24N2O4, CAS 2171990-22-8
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(5-methylpyridin-2-yl)pyrrolidine-3-carboxylic acid
CAS 2171990-22-8C26H24N2O4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C25H22N2O4, CAS 2172155-10-9
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid
CAS 2172155-10-9C25H22N2O4
4-(6-Bromopyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid chemical structure, C25H21BrN2O4, CAS 2172113-52-7
4-(6-Bromopyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid
CAS 2172113-52-7C25H21BrN2O4
4-(5-Chloropyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid chemical structure, C25H21ClN2O4, CAS 2171981-69-2
4-(5-Chloropyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid
CAS 2171981-69-2C25H21ClN2O4
2-{[3-(5-Bromopyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidin-3-yl]oxy}acetic acid chemical structure, C26H23BrN2O5, CAS 2309469-54-1
2-{[3-(5-Bromopyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidin-3-yl]oxy}acetic acid
CAS 2309469-54-1C26H23BrN2O5
4-(4-Chloropyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid chemical structure, C25H21ClN2O4, CAS 2171847-25-7
4-(4-Chloropyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid
CAS 2171847-25-7C25H21ClN2O4
4-(5-Bromopyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid chemical structure, C25H21BrN2O4, CAS 2172531-41-6
4-(5-Bromopyridin-2-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-3-carboxylic acid
CAS 2172531-41-6C25H21BrN2O4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(3-fluoropyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C25H21FN2O4, CAS 2171825-39-9
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(3-fluoropyridin-2-yl)pyrrolidine-3-carboxylic acid
CAS 2171825-39-9C25H21FN2O4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-methyl-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C26H24N2O4, CAS 2580215-78-5
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-methyl-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid
CAS 2580215-78-5C26H24N2O4
rac-(3R,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-methyl-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C26H24N2O4, CAS 2639375-68-9
rac-(3R,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-methyl-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid
CAS 2639375-68-9C26H24N2O4
(9H-Fluoren-9-yl)methyl 3-(hydroxymethyl)-3-(pyridin-2-yl)pyrrolidine-1-carboxylate chemical structure, C25H24N2O3, CAS 2764000-60-2
(9H-Fluoren-9-yl)methyl 3-(hydroxymethyl)-3-(pyridin-2-yl)pyrrolidine-1-carboxylate
CAS 2764000-60-2C25H24N2O3