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Murcko scaffold

3-(4-Oxo-3,4-dihydroquinazolin-3-yl)-2,6-piperidinedione scaffold

55 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
55
With full pages
2
Scaffold SMILES

O=C1CCC(n2cnc3ccccc3c2=O)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(4-Oxo-3,4-dihydroquinazolin-3-yl)-2,6-piperidinedione page
Murcko scaffold O=C1CCC(n2cnc3ccccc3c2=O)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 55 of 55 chemicals

3-(5-Bromo-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione chemical structure, C14H12BrN3O3, CAS 2762040-38-8
3-(5-Bromo-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione
CAS 2762040-38-8C14H12BrN3O3
3-(8-Bromo-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione chemical structure, C13H10BrN3O3, CAS 2913287-67-7
3-(8-Bromo-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione
CAS 2913287-67-7C13H10BrN3O3
3-(5-Amino-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione chemical structure, C13H12N4O3, CAS 2913338-24-4
3-(5-Amino-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione
CAS 2913338-24-4C13H12N4O3
3-(5-Bromo-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione chemical structure, C13H10BrN3O3, CAS 2913287-49-5
3-(5-Bromo-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione
CAS 2913287-49-5C13H10BrN3O3
3-(6-Azido-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione chemical structure, C13H10N6O3, CAS 2920130-23-8
3-(6-Azido-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione
CAS 2920130-23-8C13H10N6O3
(S)-3-(8-Ethynyl-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione chemical structure, C16H13N3O3, CAS 2832471-76-6
(S)-3-(8-Ethynyl-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione
CAS 2832471-76-6C16H13N3O3
2,2,2-Trifluoroethyl N-[3-(2,6-dioxopiperidin-3-yl)-2-methyl-4-oxo-3,4-dihydroquinazolin-8-yl]carbamate chemical structure, C17H15F3N4O5, CAS 3079433-40-9
2,2,2-Trifluoroethyl N-[3-(2,6-dioxopiperidin-3-yl)-2-methyl-4-oxo-3,4-dihydroquinazolin-8-yl]carbamate
CAS 3079433-40-9C17H15F3N4O5