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Murcko scaffold

3-(4-Oxo-3,4-dihydroquinazolin-3-yl)-2,6-piperidinedione scaffold

55 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
55
With full pages
5
Scaffold SMILES

O=C1CCC(n2cnc3ccccc3c2=O)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(4-Oxo-3,4-dihydroquinazolin-3-yl)-2,6-piperidinedione page
Murcko scaffold O=C1CCC(n2cnc3ccccc3c2=O)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

Glutarimide, 2-(3,4-dihydro-2-methyl-4-oxo-3-quinazolinyl)- chemical structure, C14H13N3O3, CAS 69557-32-0
Glutarimide, 2-(3,4-dihydro-2-methyl-4-oxo-3-quinazolinyl)-
CAS 69557-32-0C14H13N3O3
3-(4-Oxo-3,4-dihydroquinazolin-3-yl)-2,6-piperidinedione chemical structure, C13H11N3O3, CAS 39123-48-3
3-(4-Oxo-3,4-dihydroquinazolin-3-yl)-2,6-piperidinedione
CAS 39123-48-3C13H11N3O3
3-(5-Methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C14H13N3O3, CAS 1015474-16-4
3-(5-Methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1015474-16-4C14H13N3O3
3-(2,5-Dimethyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C15H15N3O3, CAS 1015474-17-5
3-(2,5-Dimethyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1015474-17-5C15H15N3O3
3-(5-Methoxy-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C15H15N3O4, CAS 1015474-23-3
3-(5-Methoxy-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1015474-23-3C15H15N3O4
3-(5-Fluoro-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione chemical structure, C14H12FN3O3, CAS 1015474-24-4
3-(5-Fluoro-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione
CAS 1015474-24-4C14H12FN3O3
3-(5-Chloro-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C14H12ClN3O3, CAS 1015474-25-5
3-(5-Chloro-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1015474-25-5C14H12ClN3O3
3-(5-Chloro-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C13H10ClN3O3, CAS 1015474-27-7
3-(5-Chloro-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1015474-27-7C13H10ClN3O3
3-(2-Ethyl-5-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C16H17N3O3, CAS 1015474-28-8
3-(2-Ethyl-5-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1015474-28-8C16H17N3O3
Avadomide chemical structure, C14H14N4O3, CAS 1015474-32-4
Avadomide
CAS 1015474-32-4C14H14N4O3
(3S)-3-(5-Azanyl-2-methyl-4-oxidanylidene-quinazolin-3-yl)piperidine-2,6-dione chemical structure, C14H14N4O3, CAS 1015474-78-8
(3S)-3-(5-Azanyl-2-methyl-4-oxidanylidene-quinazolin-3-yl)piperidine-2,6-dione
CAS 1015474-78-8C14H14N4O3
2-Chloro-N-(3-(2,6-dioxopiperidin-3-yl)-2-methyl-4-oxo-3,4-dihydroquinazolin-5-yl)acetamide chemical structure, C16H15ClN4O4, CAS 1015474-42-6
2-Chloro-N-(3-(2,6-dioxopiperidin-3-yl)-2-methyl-4-oxo-3,4-dihydroquinazolin-5-yl)acetamide
CAS 1015474-42-6C16H15ClN4O4
3-[5-(Aminomethyl)-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl]piperidine-2,6-dione hydrochloride chemical structure, C15H17ClN4O3, CAS 1015474-47-1
3-[5-(Aminomethyl)-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl]piperidine-2,6-dione hydrochloride
CAS 1015474-47-1C15H17ClN4O3
3-(8-Bromo-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione chemical structure, C14H12BrN3O3, CAS 1135009-03-8
3-(8-Bromo-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione
CAS 1135009-03-8C14H12BrN3O3
3-(7-Bromo-2-methyl-4-oxo-quinazolin-3-yl)piperidine-2,6-dione chemical structure, C14H12BrN3O3, CAS 1135008-81-9
3-(7-Bromo-2-methyl-4-oxo-quinazolin-3-yl)piperidine-2,6-dione
CAS 1135008-81-9C14H12BrN3O3
3-(8-Hydroxy-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione chemical structure, C14H13N3O4, CAS 1135009-06-1
3-(8-Hydroxy-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione
CAS 1135009-06-1C14H13N3O4
3-(8-Chloro-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C14H12ClN3O3, CAS 1135009-01-6
3-(8-Chloro-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1135009-01-6C14H12ClN3O3
3-(2,6-Dimethyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C15H15N3O3, CAS 1135008-16-0
3-(2,6-Dimethyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1135008-16-0C15H15N3O3
3-(6-Bromo-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione chemical structure, C14H12BrN3O3, CAS 1135008-24-0
3-(6-Bromo-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione
CAS 1135008-24-0C14H12BrN3O3
3-(6-Bromo-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C13H10BrN3O3, CAS 1135008-30-8
3-(6-Bromo-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1135008-30-8C13H10BrN3O3
3-(6-Chloro-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C14H12ClN3O3, CAS 1135008-22-8
3-(6-Chloro-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1135008-22-8C14H12ClN3O3
3-(6-Chloro-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione chemical structure, C13H10ClN3O3, CAS 1135011-34-5
3-(6-Chloro-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
CAS 1135011-34-5C13H10ClN3O3
3-(6-Amino-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione chemical structure, C14H14N4O3, CAS 1135008-35-3
3-(6-Amino-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-2,6-dione
CAS 1135008-35-3C14H14N4O3
3-(6-Hydroxy-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione chemical structure, C14H13N3O4, CAS 1135008-26-2
3-(6-Hydroxy-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione
CAS 1135008-26-2C14H13N3O4