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Murcko scaffold

Ring system with 3 rings and 21 atoms

22 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 21
Chemicals: 22
With full pages: 2

Scaffold SMILES

O=C1NC(=S)N(c2ccccc2)C(=O)C1=Cc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1NC(=S)N(c2ccccc2)C(=O)C1=Cc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

(5E)-1-(4-Fluorophenyl)-5-[(5-methylfuran-2-yl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C16H11FN2O3S, CAS 352648-69-2

(5E)-1-(4-Fluorophenyl)-5-[(5-methylfuran-2-yl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 352648-69-2C₁₆H₁₁FN₂O₃S

(5E)-1-(4-Chlorophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C15H9ClN2O3S, CAS 340213-60-7

(5E)-1-(4-Chlorophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 340213-60-7C₁₅H₉ClN₂O₃S

(5Z)-1-(4-Chlorophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C15H9ClN2O3S

(5Z)-1-(4-Chlorophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione

C₁₅H₉ClN₂O₃S

(5Z)-1-(2-Chlorophenyl)-5-[(5-methylfuran-2-yl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C16H11ClN2O3S, CAS 352343-21-6

(5Z)-1-(2-Chlorophenyl)-5-[(5-methylfuran-2-yl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 352343-21-6C₁₆H₁₁ClN₂O₃S

(5E)-1-(3,5-Dimethylphenyl)-5-[(5-methylfuran-2-yl)methylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione chemical structure, C18H16N2O3S, CAS 677017-66-2

(5E)-1-(3,5-Dimethylphenyl)-5-[(5-methylfuran-2-yl)methylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

CAS 677017-66-2C₁₈H₁₆N₂O₃S

(5E)-1-(3-Bromophenyl)-5-{[5-(diethylamino)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione chemical structure, C19H18BrN3O3S, CAS 340228-20-8

(5E)-1-(3-Bromophenyl)-5-{[5-(diethylamino)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

CAS 340228-20-8C₁₉H₁₈BrN₃O₃S

(5E)-1-(4-Chlorophenyl)-5-[[5-(diethylamino)furan-2-yl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C19H18ClN3O3S, CAS 340310-75-0

(5E)-1-(4-Chlorophenyl)-5-[[5-(diethylamino)furan-2-yl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 340310-75-0C₁₉H₁₈ClN₃O₃S

(5E)-1-(3-Chloro-2-methylphenyl)-5-[(5-methylfuran-2-yl)methylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione chemical structure, C17H13ClN2O3S, CAS 692270-67-0

(5E)-1-(3-Chloro-2-methylphenyl)-5-[(5-methylfuran-2-yl)methylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

CAS 692270-67-0C₁₇H₁₃ClN₂O₃S

(5Z)-1-(2-Fluorophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylpyrimidine-4,6(1H,5H)-dione chemical structure, C15H9FN2O3S, CAS 372495-83-5

(5Z)-1-(2-Fluorophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylpyrimidine-4,6(1H,5H)-dione

CAS 372495-83-5C₁₅H₉FN₂O₃S

(5E)-5-[(5-Bromofuran-2-yl)methylidene]-1-(4-ethoxyphenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C17H13BrN2O4S, CAS 423734-30-9

(5E)-5-[(5-Bromofuran-2-yl)methylidene]-1-(4-ethoxyphenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 423734-30-9C₁₇H₁₃BrN₂O₄S

(5E)-1-(3-Chloro-2-methylphenyl)-5-{[5-(dimethylamino)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione chemical structure, C18H16ClN3O3S, CAS 680595-76-0

(5E)-1-(3-Chloro-2-methylphenyl)-5-{[5-(dimethylamino)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

CAS 680595-76-0C₁₈H₁₆ClN₃O₃S

(5E)-1-(4-Ethoxyphenyl)-5-[(5-iodofuran-2-yl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C17H13IN2O4S, CAS 358677-66-4

(5E)-1-(4-Ethoxyphenyl)-5-[(5-iodofuran-2-yl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 358677-66-4C₁₇H₁₃IN₂O₄S

(5Z)-1-(4-Ethoxyphenyl)-5-[(5-iodofuran-2-yl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C17H13IN2O4S

(5Z)-1-(4-Ethoxyphenyl)-5-[(5-iodofuran-2-yl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione

C₁₇H₁₃IN₂O₄S

(5E)-5-[(5-Iodofuran-2-yl)methylidene]-1-(4-methoxyphenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C16H11IN2O4S, CAS 340304-16-7

(5E)-5-[(5-Iodofuran-2-yl)methylidene]-1-(4-methoxyphenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 340304-16-7C₁₆H₁₁IN₂O₄S

(5E)-5-[(5-Bromofuran-2-yl)methylidene]-1-(4-chlorophenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C15H8BrClN2O3S, CAS 340213-94-7

(5E)-5-[(5-Bromofuran-2-yl)methylidene]-1-(4-chlorophenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 340213-94-7C₁₅H₈BrClN₂O₃S

Smifh2 chemical structure, C15H9BrN2O3S, CAS 340316-62-3

CAS 340316-62-3C₁₅H₉BrN₂O₃S

(5E)-1-(4-Bromo-2-methylphenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C16H11BrN2O3S, CAS 347374-86-1

(5E)-1-(4-Bromo-2-methylphenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 347374-86-1C₁₆H₁₁BrN₂O₃S

(5Z)-1-(4-Bromo-2-methylphenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C16H11BrN2O3S

(5Z)-1-(4-Bromo-2-methylphenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione

C₁₆H₁₁BrN₂O₃S

(5E)-1-(2-Fluorophenyl)-5-[(5-iodofuran-2-yl)methylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione chemical structure, C15H8FIN2O3S, CAS 340307-07-5

(5E)-1-(2-Fluorophenyl)-5-[(5-iodofuran-2-yl)methylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

CAS 340307-07-5C₁₅H₈FIN₂O₃S

(5Z)-1-(3-Chloro-4-fluorophenyl)-5-[[5-(dimethylamino)furan-2-yl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C17H13ClFN3O3S, CAS 471848-60-9

(5Z)-1-(3-Chloro-4-fluorophenyl)-5-[[5-(dimethylamino)furan-2-yl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 471848-60-9C₁₇H₁₃ClFN₃O₃S

(5Z)-1-(2,3-Dichlorophenyl)-5-[[5-(diethylamino)furan-2-yl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C19H17Cl2N3O3S, CAS 366830-18-4

(5Z)-1-(2,3-Dichlorophenyl)-5-[[5-(diethylamino)furan-2-yl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 366830-18-4C₁₉H₁₇Cl₂N₃O₃S

(5Z)-1-(3-Chlorophenyl)-5-[[5-(diethylamino)furan-2-yl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C19H18ClN3O3S, CAS 366823-50-9

(5Z)-1-(3-Chlorophenyl)-5-[[5-(diethylamino)furan-2-yl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS 366823-50-9C₁₉H₁₈ClN₃O₃S