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Murcko scaffold

Ring system with 3 rings and 18 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
12
With full pages
1
Scaffold SMILES

c1ccc(-c2cccc(CC3CCCN3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2cccc(CC3CCCN3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Firazorexton chemical structure, C22H25F3N2O4S, CAS 2274802-95-6
Firazorexton
CAS 2274802-95-6C22H25F3N2O4S
Suntinorexton chemical structure, C23H28F2N2O4S, CAS 2274802-89-8
Suntinorexton
CAS 2274802-89-8C23H28F2N2O4S
N-[(2S,3R)-2-{[3-(3,5-Difluorophenyl)-2-fluorophenyl]methyl}-4,4-difluoropyrrolidin-3-yl]methanesulfonamide hydrochloride chemical structure, C18H18ClF5N2O2S, CAS 2460728-31-6
N-[(2S,3R)-2-{[3-(3,5-Difluorophenyl)-2-fluorophenyl]methyl}-4,4-difluoropyrrolidin-3-yl]methanesulfonamide hydrochloride
CAS 2460728-31-6C18H18ClF5N2O2S
W9QD67Rbg3 chemical structure, C18H17F5N2O2S, CAS 2460728-30-5
W9QD67Rbg3
CAS 2460728-30-5C18H17F5N2O2S
Ethanesulfonamide, N-[(2S,3R)-4,4-difluoro-2-[(2,3',5'-trifluoro[1,1'-biphenyl]-3-yl)methyl]-3-pyrrolidinyl]-, hydrochloride (1:1) chemical structure, C19H20ClF5N2O2S, CAS 2460728-34-9
Ethanesulfonamide, N-[(2S,3R)-4,4-difluoro-2-[(2,3',5'-trifluoro[1,1'-biphenyl]-3-yl)methyl]-3-pyrrolidinyl]-, hydrochloride (1:1)
CAS 2460728-34-9C19H20ClF5N2O2S
Ethanesulfonamide, N-[(2S,3R)-4,4-difluoro-2-[(2,3',5'-trifluoro[1,1'-biphenyl]-3-yl)methyl]-3-pyrrolidinyl]- chemical structure, C19H19F5N2O2S, CAS 2460728-33-8
Ethanesulfonamide, N-[(2S,3R)-4,4-difluoro-2-[(2,3',5'-trifluoro[1,1'-biphenyl]-3-yl)methyl]-3-pyrrolidinyl]-
CAS 2460728-33-8C19H19F5N2O2S
Heb5WT4qzt chemical structure, C22H23F5N2O4S, CAS 2460722-03-4
Heb5WT4qzt
CAS 2460722-03-4C22H23F5N2O4S
Oveporexton chemical structure, C23H25F5N2O4S, CAS 2460722-04-5
Oveporexton
CAS 2460722-04-5C23H25F5N2O4S
(2R,3R)-Firazorexton chemical structure, C22H25F3N2O4S, CAS 2692692-00-3
(2R,3R)-Firazorexton
CAS 2692692-00-3C22H25F3N2O4S
Firazorexton sesquihydrate chemical structure, C44H56F6N4O11S2, CAS 2861934-86-1
Firazorexton sesquihydrate
CAS 2861934-86-1C44H56F6N4O11S2
Orb2278508 chemical structure, C22H27F3N2O5S
Orb2278508
C22H27F3N2O5S
Firazorexton (hydrate) chemical structure, C23H31F3N2O5S
Firazorexton (hydrate)
C23H31F3N2O5S