Murcko scaffold
Ring system with 5 rings and 23 atoms
14 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 23
- Chemicals
- 14
- With full pages
- 5
Scaffold SMILES
c1ccc(Nc2c3c(cc4nc5ccccc5n24)CCC3)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 14 of 14 chemicals
![11-(p-Tolylamino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile chemical structure, C22H18N4, CAS 305332-32-5](/s/CORYUDHTPTWHFX-UHFFFAOYSA-N.svg)
11-(p-Tolylamino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile
CAS 305332-32-5C22H18N4
![4-Phenylamino-2,3-dihydro-1H-4a,9-diaza-cyclopenta[b]fluorene-10-carbonitrile chemical structure, C21H16N4, CAS 305331-92-4](/s/RBWAKOAIEBEJDV-UHFFFAOYSA-N.svg)
4-Phenylamino-2,3-dihydro-1H-4a,9-diaza-cyclopenta[b]fluorene-10-carbonitrile
CAS 305331-92-4C21H16N4
![4-(4-Hydroxy-phenylamino)-2,3-dihydro-1H-4a,9-diaza-cyclopenta[b]fluorene-10-carbonitrile chemical structure, C21H16N4O, CAS 305333-85-1](/s/HLBVUEBBNPWRIH-UHFFFAOYSA-N.svg)
4-(4-Hydroxy-phenylamino)-2,3-dihydro-1H-4a,9-diaza-cyclopenta[b]fluorene-10-carbonitrile
CAS 305333-85-1C21H16N4O
![11-(m-Tolylamino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile chemical structure, C22H18N4, CAS 305332-25-6](/s/FWEKJCQEKAGYDH-UHFFFAOYSA-N.svg)
11-(m-Tolylamino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile
CAS 305332-25-6C22H18N4
![11-(3,4-Dimethylanilino)-2,3-dihydro-1H-cyclopenta[4,5]pyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C23H20N4, CAS 305334-96-7](/s/HGMWDDXFUSMXNP-UHFFFAOYSA-N.svg)
11-(3,4-Dimethylanilino)-2,3-dihydro-1H-cyclopenta[4,5]pyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 305334-96-7C23H20N4
![11-((3-Chlorophenyl)amino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile chemical structure, C21H15ClN4, CAS 305333-89-5](/s/NCPXTZISEKAPME-UHFFFAOYSA-N.svg)
11-((3-Chlorophenyl)amino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile
CAS 305333-89-5C21H15ClN4
![11-(4-Chloroanilino)-2,3-dihydro-1H-cyclopenta[4,5]pyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C21H15ClN4, CAS 305331-94-6](/s/TYEDLCIGHFYJKF-UHFFFAOYSA-N.svg)
11-(4-Chloroanilino)-2,3-dihydro-1H-cyclopenta[4,5]pyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 305331-94-6C21H15ClN4
![11-((4-Bromophenyl)amino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile chemical structure, C21H15BrN4, CAS 305331-97-9](/s/BPPNOGVWDALNRX-UHFFFAOYSA-N.svg)
11-((4-Bromophenyl)amino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile
CAS 305331-97-9C21H15BrN4
![11-((2,5-Dimethylphenyl)amino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile chemical structure, C23H20N4, CAS 305332-19-8](/s/CRTCVGASRPSZOY-UHFFFAOYSA-N.svg)
11-((2,5-Dimethylphenyl)amino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile
CAS 305332-19-8C23H20N4
![11-[(4-Methoxyphenyl)amino]-2,3-dihydro-1H-cyclopenta[4,5]pyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C22H18N4O, CAS 307327-29-3](/s/CVPXXNOBDFJVRA-UHFFFAOYSA-N.svg)
11-[(4-Methoxyphenyl)amino]-2,3-dihydro-1H-cyclopenta[4,5]pyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 307327-29-3C22H18N4O
![N-(4-((4-Cyano-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridin-11-yl)amino)phenyl)acetamide chemical structure, C23H19N5O, CAS 305332-27-8](/s/YTDJZUYCPUAVAO-UHFFFAOYSA-N.svg)
N-(4-((4-Cyano-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridin-11-yl)amino)phenyl)acetamide
CAS 305332-27-8C23H19N5O
![11-((4-(Diethylamino)phenyl)amino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile chemical structure, C25H25N5, CAS 307343-18-6](/s/PTMROWAVFRKDFR-UHFFFAOYSA-N.svg)
11-((4-(Diethylamino)phenyl)amino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile
CAS 307343-18-6C25H25N5
![11-((3-Fluorophenyl)amino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile chemical structure, C21H15FN4, CAS 305334-94-5](/s/CLGKHLFZEIORRM-UHFFFAOYSA-N.svg)
11-((3-Fluorophenyl)amino)-2,3-dihydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyridine-4-carbonitrile
CAS 305334-94-5C21H15FN4
![11-(3-Methoxyanilino)-2,3-dihydro-1H-cyclopenta[4,5]pyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C22H18N4O, CAS 496970-90-2](/s/RPYJHXGSRALVLC-UHFFFAOYSA-N.svg)
11-(3-Methoxyanilino)-2,3-dihydro-1H-cyclopenta[4,5]pyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 496970-90-2C22H18N4O