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Murcko scaffold

2-[(2-Oxo-1H-pyrimidin-6-yl)sulfanyl]-N-phenylacetamide scaffold

115 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
115
With full pages
5
Scaffold SMILES

O=C(CSc1cc[nH]c(=O)n1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-[(2-Oxo-1H-pyrimidin-6-yl)sulfanyl]-N-phenylacetamide page
Murcko scaffold O=C(CSc1cc[nH]c(=O)n1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 115 chemicals

Methyl 6-methyl-4-[2-(4-methylanilino)-2-oxoethyl]sulfanyl-2-oxo-1H-pyrimidine-5-carboxylate chemical structure, C16H17N3O4S, CAS 852028-39-8
Methyl 6-methyl-4-[2-(4-methylanilino)-2-oxoethyl]sulfanyl-2-oxo-1H-pyrimidine-5-carboxylate
CAS 852028-39-8C16H17N3O4S
2-[(2-Oxo-1H-pyrimidin-6-yl)sulfanyl]-N-phenylacetamide chemical structure, C12H11N3O2S, CAS 905681-95-0
2-[(2-Oxo-1H-pyrimidin-6-yl)sulfanyl]-N-phenylacetamide
CAS 905681-95-0C12H11N3O2S
N-(3-Methylphenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide chemical structure, C13H13N3O2S, CAS 898421-18-6
N-(3-Methylphenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide
CAS 898421-18-6C13H13N3O2S
N-(4-Methylphenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide chemical structure, C13H13N3O2S, CAS 898441-08-2
N-(4-Methylphenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide
CAS 898441-08-2C13H13N3O2S
2-[(2-Oxo-1H-pyrimidin-6-yl)sulfanyl]-N-[4-(trifluoromethyl)phenyl]acetamide chemical structure, C13H10F3N3O2S, CAS 905682-77-1
2-[(2-Oxo-1H-pyrimidin-6-yl)sulfanyl]-N-[4-(trifluoromethyl)phenyl]acetamide
CAS 905682-77-1C13H10F3N3O2S
N-(4-Methoxyphenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide chemical structure, C13H13N3O3S, CAS 905682-98-6
N-(4-Methoxyphenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide
CAS 905682-98-6C13H13N3O3S
N-(4-Fluorophenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide chemical structure, C12H10FN3O2S, CAS 898421-21-1
N-(4-Fluorophenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide
CAS 898421-21-1C12H10FN3O2S
N-(2,4-Difluorophenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide chemical structure, C12H9F2N3O2S, CAS 905685-94-1
N-(2,4-Difluorophenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide
CAS 905685-94-1C12H9F2N3O2S
N-(3-Fluorophenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide chemical structure, C12H10FN3O2S, CAS 898421-27-7
N-(3-Fluorophenyl)-2-[(2-oxo-1H-pyrimidin-6-yl)sulfanyl]acetamide
CAS 898421-27-7C12H10FN3O2S
2-((6-Methyl-2-oxo-1,2-dihydropyrimidin-4-yl)thio)-N-(o-tolyl)acetamide chemical structure, C14H15N3O2S, CAS 905690-41-7
2-((6-Methyl-2-oxo-1,2-dihydropyrimidin-4-yl)thio)-N-(o-tolyl)acetamide
CAS 905690-41-7C14H15N3O2S
N-(2,3-Dimethylphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C15H17N3O2S, CAS 905690-59-7
N-(2,3-Dimethylphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide
CAS 905690-59-7C15H17N3O2S
N-(3,5-Dimethylphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C15H17N3O2S, CAS 905690-66-6
N-(3,5-Dimethylphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide
CAS 905690-66-6C15H17N3O2S
N-(2,5-Dimethylphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C15H17N3O2S, CAS 905690-73-5
N-(2,5-Dimethylphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide
CAS 905690-73-5C15H17N3O2S
N-Mesityl-2-((6-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)thio)acetamide chemical structure, C16H19N3O2S, CAS 905690-80-4
N-Mesityl-2-((6-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)thio)acetamide
CAS 905690-80-4C16H19N3O2S
N-(4-Ethylphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C15H17N3O2S, CAS 905690-87-1
N-(4-Ethylphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide
CAS 905690-87-1C15H17N3O2S
N-(2,4-Dimethylphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C15H17N3O2S, CAS 905690-94-0
N-(2,4-Dimethylphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide
CAS 905690-94-0C15H17N3O2S
2-[(6-Methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C14H12F3N3O2S, CAS 905691-00-1
2-[(6-Methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 905691-00-1C14H12F3N3O2S
2-[(6-Methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C14H12F3N3O2S, CAS 905691-06-7
2-[(6-Methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 905691-06-7C14H12F3N3O2S
2-[(6-Methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]-N-[4-(trifluoromethyl)phenyl]acetamide chemical structure, C14H12F3N3O2S, CAS 905691-12-5
2-[(6-Methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]-N-[4-(trifluoromethyl)phenyl]acetamide
CAS 905691-12-5C14H12F3N3O2S
N-(2-Methoxyphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C14H15N3O3S, CAS 905691-17-0
N-(2-Methoxyphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide
CAS 905691-17-0C14H15N3O3S
N-(3-Methoxyphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C14H15N3O3S, CAS 905691-22-7
N-(3-Methoxyphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide
CAS 905691-22-7C14H15N3O3S
N-(4-Methoxyphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C14H15N3O3S, CAS 905691-27-2
N-(4-Methoxyphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide
CAS 905691-27-2C14H15N3O3S
N-(3,4-Dimethoxyphenyl)-2-[(6-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)sulfanyl]acetamide chemical structure, C15H17N3O4S, CAS 905691-34-1
N-(3,4-Dimethoxyphenyl)-2-[(6-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)sulfanyl]acetamide
CAS 905691-34-1C15H17N3O4S
N-(2,4-Dimethoxyphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C15H17N3O4S, CAS 905691-40-9
N-(2,4-Dimethoxyphenyl)-2-[(6-methyl-2-oxo-1H-pyrimidin-4-yl)sulfanyl]acetamide
CAS 905691-40-9C15H17N3O4S