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Murcko scaffold

Ring system with 4 rings and 22 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
9
With full pages
4
Scaffold SMILES

O=C(Nc1cccs1)C1c2ccccc2Oc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccs1)C1c2ccccc2Oc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

Ethyl 4,5-dimethyl-2-(9H-xanthene-9-carbonylamino)thiophene-3-carboxylate chemical structure, C23H21NO4S, CAS 560077-21-6
Ethyl 4,5-dimethyl-2-(9H-xanthene-9-carbonylamino)thiophene-3-carboxylate
CAS 560077-21-6C23H21NO4S
2-N,2-N-diethyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2,4-dicarboxamide chemical structure, C25H25N3O4S, CAS 328286-60-8
2-N,2-N-diethyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2,4-dicarboxamide
CAS 328286-60-8C25H25N3O4S
Ethyl 4-carbamoyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate chemical structure, C23H20N2O5S, CAS 5698-18-0
Ethyl 4-carbamoyl-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate
CAS 5698-18-0C23H20N2O5S
Ethyl 5-acetyl-4-methyl-2-[(9H-xanthen-9-ylcarbonyl)amino]-3-thiophenecarboxylate chemical structure, C24H21NO5S, CAS 329737-95-3
Ethyl 5-acetyl-4-methyl-2-[(9H-xanthen-9-ylcarbonyl)amino]-3-thiophenecarboxylate
CAS 329737-95-3C24H21NO5S
Propan-2-yl 4-cyano-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate chemical structure, C24H20N2O4S, CAS 549517-16-0
Propan-2-yl 4-cyano-3-methyl-5-(9H-xanthene-9-carbonylamino)thiophene-2-carboxylate
CAS 549517-16-0C24H20N2O4S
Isopropyl 4-ethyl-5-methyl-2-[(9H-xanthen-9-ylcarbonyl)amino]-3-thiophenecarboxylate chemical structure, C25H25NO4S, CAS 549491-94-3
Isopropyl 4-ethyl-5-methyl-2-[(9H-xanthen-9-ylcarbonyl)amino]-3-thiophenecarboxylate
CAS 549491-94-3C25H25NO4S
Isopropyl 4,5-dimethyl-2-[(9H-xanthen-9-ylcarbonyl)amino]-3-thiophenecarboxylate chemical structure, C24H23NO4S, CAS 560091-37-4
Isopropyl 4,5-dimethyl-2-[(9H-xanthen-9-ylcarbonyl)amino]-3-thiophenecarboxylate
CAS 560091-37-4C24H23NO4S
Methyl 5-(dimethylcarbamoyl)-4-methyl-2-(9H-xanthene-9-carbonylamino)thiophene-3-carboxylate chemical structure, C24H22N2O5S, CAS 545438-00-4
Methyl 5-(dimethylcarbamoyl)-4-methyl-2-(9H-xanthene-9-carbonylamino)thiophene-3-carboxylate
CAS 545438-00-4C24H22N2O5S
Methyl 2-(9H-xanthene-9-carboxamido)thiophene-3-carboxylate chemical structure, C20H15NO4S, CAS 1172056-95-9
Methyl 2-(9H-xanthene-9-carboxamido)thiophene-3-carboxylate
CAS 1172056-95-9C20H15NO4S