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Murcko scaffold

Ring system with 3 rings and 18 atoms

37 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
37
With full pages
6
Scaffold SMILES

O=c1ccc2cccc(CN3CCCCC3)c2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccc2cccc(CN3CCCCC3)c2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

Coumarin, 7-hydroxy-8-(piperidinomethyl)-4-propyl- chemical structure, C18H23NO3, CAS 10549-64-1
Coumarin, 7-hydroxy-8-(piperidinomethyl)-4-propyl-
CAS 10549-64-1C18H23NO3
Coumarin, 7-hydroxy-4-methyl-8-(piperidinomethyl)-, hydrochloride chemical structure, C16H20ClNO3, CAS 10550-19-3
Coumarin, 7-hydroxy-4-methyl-8-(piperidinomethyl)-, hydrochloride
CAS 10550-19-3C16H20ClNO3
RefChem:357233 chemical structure, C16H19NO3, CAS 10549-62-9
RefChem:357233
CAS 10549-62-9C16H19NO3
Coumarin, 7-hydroxy-4-methyl-8-(piperidinomethyl)-, nicotinate (salt) chemical structure, C22H24N2O5, CAS 10550-20-6
Coumarin, 7-hydroxy-4-methyl-8-(piperidinomethyl)-, nicotinate (salt)
CAS 10550-20-6C22H24N2O5
Coumarin, 7-hydroxy-4-methyl-8-(piperidinomethyl)-4-methyl-, isonicotinate (salt) chemical structure, C22H24N2O5, CAS 10550-22-8
Coumarin, 7-hydroxy-4-methyl-8-(piperidinomethyl)-4-methyl-, isonicotinate (salt)
CAS 10550-22-8C22H24N2O5
Coumarin, 7-hydroxy-4-methyl-8-(piperidinomethyl)-, picolinate (salt) chemical structure, C22H24N2O5, CAS 10550-23-9
Coumarin, 7-hydroxy-4-methyl-8-(piperidinomethyl)-, picolinate (salt)
CAS 10550-23-9C22H24N2O5
Coumarin, 7-hydroxy-8-(piperidinomethyl)-4-propyl-, nicotinate (salt) chemical structure, C24H28N2O5, CAS 10550-24-0
Coumarin, 7-hydroxy-8-(piperidinomethyl)-4-propyl-, nicotinate (salt)
CAS 10550-24-0C24H28N2O5
Coumarin, 6,7-dihydroxy-4-methyl-8-(piperidinomethyl)-, hydrochloride chemical structure, C16H20ClNO4, CAS 93027-88-4
Coumarin, 6,7-dihydroxy-4-methyl-8-(piperidinomethyl)-, hydrochloride
CAS 93027-88-4C16H20ClNO4
Coumarin, 6,7-dihydroxy-8-(piperidinomethyl)-, hydrochloride chemical structure, C15H18ClNO4, CAS 94027-23-3
Coumarin, 6,7-dihydroxy-8-(piperidinomethyl)-, hydrochloride
CAS 94027-23-3C15H18ClNO4
6-Chloro-7-hydroxy-4-methyl-8-[(4-methylpiperidin-1-yl)methyl]chromen-2-one chemical structure, C17H20ClNO3, CAS 307535-50-8
6-Chloro-7-hydroxy-4-methyl-8-[(4-methylpiperidin-1-yl)methyl]chromen-2-one
CAS 307535-50-8C17H20ClNO3
6-Chloro-7-hydroxy-4-methyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C16H18ClNO3, CAS 14003-87-3
6-Chloro-7-hydroxy-4-methyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 14003-87-3C16H18ClNO3
6-Chloro-7-hydroxy-3,4-dimethyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H20ClNO3, CAS 840508-92-1
6-Chloro-7-hydroxy-3,4-dimethyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 840508-92-1C17H20ClNO3
6-Chloro-3-ethyl-7-hydroxy-4-methyl-8-(piperidin-1-ylmethyl)chromen-2-one chemical structure, C18H22ClNO3, CAS 573973-05-4
6-Chloro-3-ethyl-7-hydroxy-4-methyl-8-(piperidin-1-ylmethyl)chromen-2-one
CAS 573973-05-4C18H22ClNO3
6-Chloro-7-hydroxy-3,4-dimethyl-8-[(3-methylpiperidin-1-yl)methyl]chromen-2-one chemical structure, C18H22ClNO3, CAS 577983-52-9
6-Chloro-7-hydroxy-3,4-dimethyl-8-[(3-methylpiperidin-1-yl)methyl]chromen-2-one
CAS 577983-52-9C18H22ClNO3
7-Hydroxy-8-[(4-methylpiperidin-1-yl)methyl]-4-propyl-2H-chromen-2-one chemical structure, C19H25NO3, CAS 313471-33-9
7-Hydroxy-8-[(4-methylpiperidin-1-yl)methyl]-4-propyl-2H-chromen-2-one
CAS 313471-33-9C19H25NO3
4-Ethyl-7-hydroxy-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H21NO3, CAS 858742-30-0
4-Ethyl-7-hydroxy-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 858742-30-0C17H21NO3
Methyl [7-hydroxy-4-methyl-2-oxo-8-(piperidin-1-ylmethyl)-2H-chromen-3-yl]acetate chemical structure, C19H23NO5, CAS 858744-43-1
Methyl [7-hydroxy-4-methyl-2-oxo-8-(piperidin-1-ylmethyl)-2H-chromen-3-yl]acetate
CAS 858744-43-1C19H23NO5
7-Hydroxy-3,4-dimethyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H21NO3, CAS 804432-51-7
7-Hydroxy-3,4-dimethyl-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 804432-51-7C17H21NO3
6-Chloro-4-ethyl-7-hydroxy-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H20ClNO3, CAS 840512-17-6
6-Chloro-4-ethyl-7-hydroxy-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 840512-17-6C17H20ClNO3
4-Butyl-7-hydroxy-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C19H25NO3, CAS 573709-93-0
4-Butyl-7-hydroxy-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 573709-93-0C19H25NO3
4-Butyl-6-chloro-7-hydroxy-8-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C19H24ClNO3, CAS 578758-72-2
4-Butyl-6-chloro-7-hydroxy-8-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 578758-72-2C19H24ClNO3
6-Chloro-3-hexyl-7-hydroxy-4-methyl-8-(piperidinomethyl)-2H-chromen-2-one chemical structure, C22H30ClNO3, CAS 577999-66-7
6-Chloro-3-hexyl-7-hydroxy-4-methyl-8-(piperidinomethyl)-2H-chromen-2-one
CAS 577999-66-7C22H30ClNO3
8-(2-Ethyl-piperidin-1-ylmethyl)-7-hydroxy-4-methyl-chromen-2-one chemical structure, C18H23NO3, CAS 307535-35-9
8-(2-Ethyl-piperidin-1-ylmethyl)-7-hydroxy-4-methyl-chromen-2-one
CAS 307535-35-9C18H23NO3
6-Chloro-7-hydroxy-4-methyl-8-[(2-methylpiperidyl)methyl]chromen-2-one chemical structure, C17H20ClNO3, CAS 307535-51-9
6-Chloro-7-hydroxy-4-methyl-8-[(2-methylpiperidyl)methyl]chromen-2-one
CAS 307535-51-9C17H20ClNO3