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Murcko scaffold

Ring system with 3 rings and 18 atoms

69 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
69
With full pages
41
Scaffold SMILES

O=c1cc(CN2CCCCC2)c2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(CN2CCCCC2)c2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 69 chemicals

6-Chloro-5,7-dimethyl-4-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C18H22ClNO2, CAS 896847-45-3
6-Chloro-5,7-dimethyl-4-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 896847-45-3C18H22ClNO2
6-Ethyl-4-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C18H23NO2, CAS 896848-20-7
6-Ethyl-4-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 896848-20-7C18H23NO2
6-Methyl-4-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C17H21NO2, CAS 899385-10-5
6-Methyl-4-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 899385-10-5C17H21NO2
6-Chloro-5,7-dimethyl-4-((2-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C18H22ClNO2, CAS 900285-90-7
6-Chloro-5,7-dimethyl-4-((2-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 900285-90-7C18H22ClNO2
6,7-Dimethyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H21NO2, CAS 485821-97-4
6,7-Dimethyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 485821-97-4C17H21NO2
Ethyl 1-[(7-methyl-2-oxochromen-4-yl)methyl]piperidine-4-carboxylate chemical structure, C19H23NO4, CAS 846063-59-0
Ethyl 1-[(7-methyl-2-oxochromen-4-yl)methyl]piperidine-4-carboxylate
CAS 846063-59-0C19H23NO4
7,8-Dimethyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H21NO2, CAS 846600-66-6
7,8-Dimethyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 846600-66-6C17H21NO2
Ethyl 1-[(7-methoxy-2-oxo-2H-chromen-4-yl)methyl]piperidine-4-carboxylate chemical structure, C19H23NO5, CAS 847751-10-4
Ethyl 1-[(7-methoxy-2-oxo-2H-chromen-4-yl)methyl]piperidine-4-carboxylate
CAS 847751-10-4C19H23NO5
6-Hydroxy-7-methyl-4-[(4-methylpiperidin-1-yl)methyl]-2H-chromen-2-one chemical structure, C17H21NO3, CAS 859858-11-0
6-Hydroxy-7-methyl-4-[(4-methylpiperidin-1-yl)methyl]-2H-chromen-2-one
CAS 859858-11-0C17H21NO3
6-Ethyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H21NO2, CAS 859865-51-3
6-Ethyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 859865-51-3C17H21NO2
4-(Piperidin-1-ylmethyl)-6-propan-2-ylchromen-2-one chemical structure, C18H23NO2, CAS 859864-50-9
4-(Piperidin-1-ylmethyl)-6-propan-2-ylchromen-2-one
CAS 859864-50-9C18H23NO2
7-Methyl-4-(piperidin-1-ylmethyl)chromen-2-one chemical structure, C16H19NO2, CAS 84097-09-6
7-Methyl-4-(piperidin-1-ylmethyl)chromen-2-one
CAS 84097-09-6C16H19NO2
Ethyl 1-[(6-hydroxy-7-methyl-2-oxochromen-4-yl)methyl]piperidine-4-carboxylate chemical structure, C19H23NO5, CAS 859108-07-9
Ethyl 1-[(6-hydroxy-7-methyl-2-oxochromen-4-yl)methyl]piperidine-4-carboxylate
CAS 859108-07-9C19H23NO5
7-Methoxy-4-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C16H19NO3, CAS 66762-38-7
7-Methoxy-4-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 66762-38-7C16H19NO3
6,8-Dimethyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H21NO2, CAS 485821-98-5
6,8-Dimethyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 485821-98-5C17H21NO2
5,7-Dimethyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C17H21NO2, CAS 485821-96-3
5,7-Dimethyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 485821-96-3C17H21NO2
6-Methyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C16H19NO2, CAS 84097-16-5
6-Methyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 84097-16-5C16H19NO2
6-Hydroxy-7-methyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one chemical structure, C16H19NO3, CAS 859112-95-1
6-Hydroxy-7-methyl-4-(piperidin-1-ylmethyl)-2H-chromen-2-one
CAS 859112-95-1C16H19NO3
6,8-Dimethyl-4-[(4-methylpiperidin-1-yl)methyl]chromen-2-one chemical structure, C18H23NO2, CAS 896594-06-2
6,8-Dimethyl-4-[(4-methylpiperidin-1-yl)methyl]chromen-2-one
CAS 896594-06-2C18H23NO2
6-Chloro-7-methyl-4-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C17H20ClNO2, CAS 848065-80-5
6-Chloro-7-methyl-4-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 848065-80-5C17H20ClNO2
5,7,8-Trimethyl-4-[(4-methylpiperidin-1-yl)methyl]chromen-2-one chemical structure, C19H25NO2, CAS 896855-38-2
5,7,8-Trimethyl-4-[(4-methylpiperidin-1-yl)methyl]chromen-2-one
CAS 896855-38-2C19H25NO2
6,7-Dimethyl-4-[(4-methylpiperidin-1-yl)methyl]chromen-2-one chemical structure, C18H23NO2, CAS 848914-06-7
6,7-Dimethyl-4-[(4-methylpiperidin-1-yl)methyl]chromen-2-one
CAS 848914-06-7C18H23NO2
5,7-Dimethyl-4-[(4-methylpiperidyl)methyl]chromen-2-one chemical structure, C18H23NO2, CAS 899393-41-0
5,7-Dimethyl-4-[(4-methylpiperidyl)methyl]chromen-2-one
CAS 899393-41-0C18H23NO2
7-Methyl-4-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one chemical structure, C17H21NO2, CAS 750626-37-0
7-Methyl-4-((4-methylpiperidin-1-yl)methyl)-2H-chromen-2-one
CAS 750626-37-0C17H21NO2