Murcko scaffold
Ring system with 2 rings and 17 atoms
443 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 17
- Chemicals
- 443
- With full pages
- 77
Scaffold SMILES
O=C(CSc1ccccc1)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 193 to 240 of 443 chemicals
![N-(4-Methoxyphenyl)-2-{[3-(trifluoromethyl)phenyl]sulfanyl}acetamide chemical structure, C16H14F3NO2S, CAS 339097-43-7](/s/CEZLSSOVJUJTJF-UHFFFAOYSA-N.svg)
N-(4-Methoxyphenyl)-2-{[3-(trifluoromethyl)phenyl]sulfanyl}acetamide
CAS 339097-43-7C16H14F3NO2S
![2-[(3-Chlorophenyl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C15H11ClF3NOS, CAS 339097-74-4](/s/OBQFUBYEUCQHIH-UHFFFAOYSA-N.svg)
2-[(3-Chlorophenyl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 339097-74-4C15H11ClF3NOS
![2-[(4-Methoxyphenyl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C16H14F3NO2S, CAS 339097-75-5](/s/SELHXJRQFBEHOR-UHFFFAOYSA-N.svg)
2-[(4-Methoxyphenyl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 339097-75-5C16H14F3NO2S
![N-(2-Chlorophenyl)-2-[(3-chlorophenyl)sulfanyl]acetamide chemical structure, C14H11Cl2NOS, CAS 339097-81-3](/s/UIABWTSKODHWQJ-UHFFFAOYSA-N.svg)
N-(2-Chlorophenyl)-2-[(3-chlorophenyl)sulfanyl]acetamide
CAS 339097-81-3C14H11Cl2NOS
![N-(2-Chlorophenyl)-2-[(4-methoxyphenyl)sulfanyl]acetamide chemical structure, C15H14ClNO2S, CAS 339097-83-5](/s/RVTNIIXEZGCJIR-UHFFFAOYSA-N.svg)
N-(2-Chlorophenyl)-2-[(4-methoxyphenyl)sulfanyl]acetamide
CAS 339097-83-5C15H14ClNO2S
![N-(2-Chlorophenyl)-2-[(4-fluorophenyl)sulfanyl]acetamide chemical structure, C14H11ClFNOS, CAS 339097-85-7](/s/SFBZIEVIHKMVKP-UHFFFAOYSA-N.svg)
N-(2-Chlorophenyl)-2-[(4-fluorophenyl)sulfanyl]acetamide
CAS 339097-85-7C14H11ClFNOS
![N-(2-Chlorophenyl)-2-[(3,4-dichlorophenyl)sulfanyl]acetamide chemical structure, C14H10Cl3NOS, CAS 339097-95-9](/s/SMBLUMYNIRAHRH-UHFFFAOYSA-N.svg)
N-(2-Chlorophenyl)-2-[(3,4-dichlorophenyl)sulfanyl]acetamide
CAS 339097-95-9C14H10Cl3NOS
![N-(2-Chlorophenyl)-2-{[3-(trifluoromethyl)phenyl]sulfanyl}acetamide chemical structure, C15H11ClF3NOS, CAS 339097-96-0](/s/HZINYGQTVIBMKB-UHFFFAOYSA-N.svg)
N-(2-Chlorophenyl)-2-{[3-(trifluoromethyl)phenyl]sulfanyl}acetamide
CAS 339097-96-0C15H11ClF3NOS
![N-(2,4-Dichlorophenyl)-2-[(4-fluorophenyl)sulfanyl]acetamide chemical structure, C14H10Cl2FNOS, CAS 339107-56-1](/s/KEVVNDAOIHHHET-UHFFFAOYSA-N.svg)
N-(2,4-Dichlorophenyl)-2-[(4-fluorophenyl)sulfanyl]acetamide
CAS 339107-56-1C14H10Cl2FNOS
![2-[(2-Chlorophenyl)sulfanyl]-N-(2,4-dichlorophenyl)acetamide chemical structure, C14H10Cl3NOS, CAS 339107-58-3](/s/OMHXOEQGSODYII-UHFFFAOYSA-N.svg)
2-[(2-Chlorophenyl)sulfanyl]-N-(2,4-dichlorophenyl)acetamide
CAS 339107-58-3C14H10Cl3NOS
![2-[(3-Chlorophenyl)sulfanyl]-N-(2,4-dichlorophenyl)acetamide chemical structure, C14H10Cl3NOS, CAS 400089-21-6](/s/LMFDWQUJHPCPRZ-UHFFFAOYSA-N.svg)
2-[(3-Chlorophenyl)sulfanyl]-N-(2,4-dichlorophenyl)acetamide
CAS 400089-21-6C14H10Cl3NOS
![N-(2,4-Dichlorophenyl)-2-{[3-(trifluoromethyl)phenyl]sulfanyl}acetamide chemical structure, C15H10Cl2F3NOS, CAS 339107-73-2](/s/FAODIJVFNDXZLK-UHFFFAOYSA-N.svg)
N-(2,4-Dichlorophenyl)-2-{[3-(trifluoromethyl)phenyl]sulfanyl}acetamide
CAS 339107-73-2C15H10Cl2F3NOS
![N-(2,4-Dichlorophenyl)-2-[(4-methoxyphenyl)sulfanyl]acetamide chemical structure, C15H13Cl2NO2S, CAS 339107-74-3](/s/NPDFHPMUPDAOGG-UHFFFAOYSA-N.svg)
N-(2,4-Dichlorophenyl)-2-[(4-methoxyphenyl)sulfanyl]acetamide
CAS 339107-74-3C15H13Cl2NO2S
![2-[(3-Chlorophenyl)sulfanyl]-N-methyl-N-phenylacetamide chemical structure, C15H14ClNOS, CAS 339107-92-5](/s/ARFTYHFNHICAKI-UHFFFAOYSA-N.svg)
2-[(3-Chlorophenyl)sulfanyl]-N-methyl-N-phenylacetamide
CAS 339107-92-5C15H14ClNOS
![2-[(2-Aminophenyl)sulfanyl]-N-(2,4-dichlorophenyl)acetamide chemical structure, C14H12Cl2N2OS, CAS 92291-38-8](/s/XBNQGBQBXLPHNC-UHFFFAOYSA-N.svg)
2-[(2-Aminophenyl)sulfanyl]-N-(2,4-dichlorophenyl)acetamide
CAS 92291-38-8C14H12Cl2N2OS
![Methyl 2-{[N-(3-methoxyphenyl)carbamoyl]methylthio}benzoate chemical structure, C17H17NO4S, CAS 132390-52-4](/s/RBDCJZMPLMZQHT-UHFFFAOYSA-N.svg)
Methyl 2-{[N-(3-methoxyphenyl)carbamoyl]methylthio}benzoate
CAS 132390-52-4C17H17NO4S
2-((2-Oxo-2-((2-(trifluoromethyl)phenyl)amino)ethyl)thio)benzoic acid
CAS 450385-28-1C16H12F3NO3S
![2-{[2-(4-Chloroanilino)-2-oxoethyl]sulfanyl}benzoic acid chemical structure, C15H12ClNO3S, CAS 540774-65-0](/s/VQQFNBRBIAVAIZ-UHFFFAOYSA-N.svg)
2-{[2-(4-Chloroanilino)-2-oxoethyl]sulfanyl}benzoic acid
CAS 540774-65-0C15H12ClNO3S
![2-[(4-Bromophenyl)sulfanyl]-N-(4-fluoro-3-nitrophenyl)acetamide chemical structure, C14H10BrFN2O3S, CAS 380490-98-2](/s/BGLCBWUVGSXUDC-UHFFFAOYSA-N.svg)
2-[(4-Bromophenyl)sulfanyl]-N-(4-fluoro-3-nitrophenyl)acetamide
CAS 380490-98-2C14H10BrFN2O3S
![2-[(4-Chlorophenyl)sulfanyl]-N-(4-fluoro-3-nitrophenyl)acetamide chemical structure, C14H10ClFN2O3S, CAS 532960-93-3](/s/KUOZOYMTCQFJBX-UHFFFAOYSA-N.svg)
2-[(4-Chlorophenyl)sulfanyl]-N-(4-fluoro-3-nitrophenyl)acetamide
CAS 532960-93-3C14H10ClFN2O3S
![2-[(4-Chlorophenyl)sulfanyl]-N-(2-methoxy-5-nitrophenyl)acetamide chemical structure, C15H13ClN2O4S, CAS 461399-66-6](/s/DCKPHZJOPPROGI-UHFFFAOYSA-N.svg)
2-[(4-Chlorophenyl)sulfanyl]-N-(2-methoxy-5-nitrophenyl)acetamide
CAS 461399-66-6C15H13ClN2O4S
![2-[(4-Chlorophenyl)sulfanyl]-N-[4-(trifluoromethyl)phenyl]acetamide chemical structure, C15H11ClF3NOS, CAS 746613-17-2](/s/LWYGVVBPSFBQDX-UHFFFAOYSA-N.svg)
2-[(4-Chlorophenyl)sulfanyl]-N-[4-(trifluoromethyl)phenyl]acetamide
CAS 746613-17-2C15H11ClF3NOS
N-(4-Ethylphenyl)-2-((4-fluorophenyl)thio)acetamide
CAS 763125-46-8C16H16FNOS
N-(4-Acetamidophenyl)-2-(4-fluorophenyl)sulfanylacetamide
CAS 757229-47-3C16H15FN2O2S
- N-(2,6-Dichloro-3-methyl-phenyl)-2-(3,4-dimethylphenyl)sulfanyl-acetamide5522-92-9C17H17Cl2NOS
- 2-(Phenylsulfanyl)-N-(3,4,5-trimethoxyphenyl)acetamide775317-10-7C17H19NO4S
- 2-(2,4-Dichlorophenyl)sulfanyl-N-(4-methylphenyl)acetamide327074-99-7C15H13Cl2NOS
- N-(2-Methyl-5-nitrophenyl)-2-(phenylsulfanyl)acetamide724735-10-8C15H14N2O3S
- N-(4-Butylphenyl)-2-(phenylsulfanyl)acetamide724735-05-1C18H21NOS
- N-[4-({[(4-Chlorophenyl)sulfanyl]acetyl}amino)-2-methoxyphenyl]pentanamide527748-44-3C20H23ClN2O3S
- N-[4-(Butylsulfamoyl)phenyl]-2-phenylsulfanylacetamide600138-68-9C18H22N2O3S2
- N-tert-Butyl-3-[[2-(4-chlorophenyl)sulfanylacetyl]amino]benzamide500263-21-8C19H21ClN2O2S
- 2-(4-Chlorophenyl)sulfanyl-N-(5-fluoro-2-methylphenyl)acetamide592546-06-0C15H13ClFNOS
- N-(4-Acetylphenyl)-2-[(4-fluorophenyl)sulfanyl]acetamide693804-07-8C16H14FNO2S
- N-(5-Chloro-2-methoxyphenyl)-2-(4-fluorophenyl)sulfanylacetamide693808-18-3C15H13ClFNO2S
- 3-[[2-(4-Chlorophenyl)sulfanylacetyl]amino]-N-(2-methylpropyl)benzamide693809-00-6C19H21ClN2O2S
- 5-Bromo-2-({[(4-methylphenyl)sulfanyl]acetyl}amino)benzoic acid518022-79-2C16H14BrNO3S
- 3-({[(4-Chlorophenyl)sulfanyl]acetyl}amino)benzoic acid701253-34-1C15H12ClNO3S
- N-(tert-Butyl)-3-({[(4-methylphenyl)thio]acetyl}amino)benzamide665025-94-5C20H24N2O2S
- N-(4-Methyl-3-nitrophenyl)-2-phenylsulfanylacetamide824422-07-3C15H14N2O3S
- N-(2-Methoxyethyl)-2-[[2-(4-methylphenyl)sulfanylacetyl]amino]benzamide708215-13-8C19H22N2O3S
- 2-(2-Aminophenyl)sulfanyl-N-(4-bromo-2,3-dimethylphenyl)acetamide708281-34-9C16H17BrN2OS
- 2-(4-Bromophenyl)sulfanyl-N-(3-chloro-4-methoxyphenyl)acetamide708991-81-5C15H13BrClNO2S
- 2-(4-tert-Butylphenyl)sulfanyl-N-(3,4,5-trimethoxyphenyl)acetamide825656-33-5C21H27NO4S
- 2-((4-Fluorophenyl)thio)-N-(4-sulfamoylphenyl)acetamide831238-42-7C14H13FN2O3S2
- N-(5-Chloro-2-hydroxyphenyl)-2-(4-fluorophenyl)sulfanylacetamide832685-12-8C14H11ClFNO2S
- N-(4-Ethylphenyl)-2-(phenylsulfanyl)acetamide432523-91-6C16H17NOS
- Propyl 4-(2-phenylthioacetylamino)benzoate432540-10-8C18H19NO3S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1ccccc1476 chemicals
O=C(NN=Cc1ccccc1)c1ccccc1265 chemicals
O=C(C=Cc1ccccc1)Nc1ccccc1175 chemicals
O=C(CCc1ccccc1)Nc1ccccc1153 chemicals
O=C(NCCc1ccccc1)c1ccccc1147 chemicals
S=C(NCc1ccccc1)Nc1ccccc1127 chemicals
O=C(CCNc1ccccc1)c1ccccc1120 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccccc196 chemicals
O=S(=O)(NCCc1ccccc1)c1ccccc183 chemicals
O=C(CNc1ccccc1)Nc1ccccc183 chemicals
c1ccc(CCNCc2ccccc2)cc173 chemicals
O=C(NCc1ccccc1)Nc1ccccc171 chemicals