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Murcko scaffold

Ring system with 3 rings and 17 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
10
With full pages
5
Scaffold SMILES

O=C1NC=NC1=C1CCNC(=O)c2[nH]ccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC=NC1=C1CCNC(=O)c2[nH]ccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Hymenialdisine chemical structure, C11H10BrN5O2, CAS 95569-43-0
Hymenialdisine
CAS 95569-43-0C11H10BrN5O2
(4E)-4-(2-Amino-4-oxo-1H-imidazol-5-ylidene)-2-bromo-1,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one chemical structure, C11H10BrN5O2, CAS 82005-12-7
(4E)-4-(2-Amino-4-oxo-1H-imidazol-5-ylidene)-2-bromo-1,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one
CAS 82005-12-7C11H10BrN5O2
(4Z)-4-(2-Amino-5-oxo-3,5-dihydro-4H-imidazol-4-ylidene)-2,3-dichloro-4,5,6,7-tetrahydropyrrolo[2,3-C]azepin-8(1H)-one chemical structure, C11H9Cl2N5O2, CAS 693222-47-8
(4Z)-4-(2-Amino-5-oxo-3,5-dihydro-4H-imidazol-4-ylidene)-2,3-dichloro-4,5,6,7-tetrahydropyrrolo[2,3-C]azepin-8(1H)-one
CAS 693222-47-8C11H9Cl2N5O2
Debromohymenialdisine chemical structure, C11H11N5O2, CAS 125118-55-0
Debromohymenialdisine
CAS 125118-55-0C11H11N5O2
4-(2-Amino-5-oxo-1H-imidazol-4-ylidene)-2-bromo-1,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one chemical structure, C11H10BrN5O2, CAS 186819-96-5
4-(2-Amino-5-oxo-1H-imidazol-4-ylidene)-2-bromo-1,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one
CAS 186819-96-5C11H10BrN5O2
(Z)-3-Bromohymenialdisine chemical structure, C11H9Br2N5O2, CAS 175421-15-5
(Z)-3-Bromohymenialdisine
CAS 175421-15-5C11H9Br2N5O2
(4E)-4-(2-Amino-5-oxo-1H-imidazol-4-ylidene)-3-bromo-1,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one chemical structure, C11H10BrN5O2, CAS 206443-95-0
(4E)-4-(2-Amino-5-oxo-1H-imidazol-4-ylidene)-3-bromo-1,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one
CAS 206443-95-0C11H10BrN5O2
Hymenialdisine methanoate chemical structure, C12H14BrN5O3, CAS 84094-94-0
Hymenialdisine methanoate
CAS 84094-94-0C12H14BrN5O3
Hymenialdisine-d4 chemical structure, C11H10BrN5O2, CAS 1185240-30-5
Hymenialdisine-d4
CAS 1185240-30-5C11H10BrN5O2
Hymenialdisine hydrochloride chemical structure, C11H11BrClN5O2, CAS 329181-19-3
Hymenialdisine hydrochloride
CAS 329181-19-3C11H11BrClN5O2