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Murcko scaffold

Ring system with 3 rings and 22 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
19
With full pages
6
Scaffold SMILES

O=C(COc1ccccc1)NN=Cc1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NN=Cc1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

2-(2,3-Dimethylphenoxy)acetic acid 2-[(1-methyl-1H-indol-3-yl)methylene]hydrazide chemical structure, C20H21N3O2, CAS 862680-56-6
2-(2,3-Dimethylphenoxy)acetic acid 2-[(1-methyl-1H-indol-3-yl)methylene]hydrazide
CAS 862680-56-6C20H21N3O2
N-[(E)-(1-Methylindol-3-yl)methylideneamino]-2-(2-methylphenoxy)acetamide chemical structure, C19H19N3O2, CAS 350042-88-5
N-[(E)-(1-Methylindol-3-yl)methylideneamino]-2-(2-methylphenoxy)acetamide
CAS 350042-88-5C19H19N3O2
N-[(E)-(1,2-Dimethylindol-3-yl)methylideneamino]-2-(2-nitrophenoxy)acetamide chemical structure, C19H18N4O4, CAS 339224-46-3
N-[(E)-(1,2-Dimethylindol-3-yl)methylideneamino]-2-(2-nitrophenoxy)acetamide
CAS 339224-46-3C19H18N4O4
N-[(E)-(1-Methylindol-3-yl)methylideneamino]-2-(4-methylphenoxy)acetamide chemical structure, C19H19N3O2, CAS 330833-55-1
N-[(E)-(1-Methylindol-3-yl)methylideneamino]-2-(4-methylphenoxy)acetamide
CAS 330833-55-1C19H19N3O2
2-(2-Bromo-4-chlorophenoxy)-N'-[(E)-(1,2-dimethyl-1H-indol-3-yl)methylidene]acetohydrazide chemical structure, C19H17BrClN3O2, CAS 324009-67-8
2-(2-Bromo-4-chlorophenoxy)-N'-[(E)-(1,2-dimethyl-1H-indol-3-yl)methylidene]acetohydrazide
CAS 324009-67-8C19H17BrClN3O2
2-(2,4-Dichlorophenoxy)-N-[(E)-(1-methylindol-3-yl)methylideneamino]acetamide chemical structure, C18H15Cl2N3O2, CAS 366460-54-0
2-(2,4-Dichlorophenoxy)-N-[(E)-(1-methylindol-3-yl)methylideneamino]acetamide
CAS 366460-54-0C18H15Cl2N3O2
N-[(E)-(1,2-Dimethylindol-3-yl)methylideneamino]-2-(4-methylphenoxy)acetamide chemical structure, C20H21N3O2, CAS 413581-47-2
N-[(E)-(1,2-Dimethylindol-3-yl)methylideneamino]-2-(4-methylphenoxy)acetamide
CAS 413581-47-2C20H21N3O2
N-[(E)-(1,2-Dimethylindol-3-yl)methylideneamino]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamide chemical structure, C27H35N3O2, CAS 413581-53-0
N-[(E)-(1,2-Dimethylindol-3-yl)methylideneamino]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamide
CAS 413581-53-0C27H35N3O2
2-{2-Nitrophenoxy}-N'-[(1-methyl-1H-indol-3-yl)methylene]acetohydrazide chemical structure, C18H16N4O4, CAS 496774-92-6
2-{2-Nitrophenoxy}-N'-[(1-methyl-1H-indol-3-yl)methylene]acetohydrazide
CAS 496774-92-6C18H16N4O4
2-(4-Chloro-2-methylphenoxy)-N'-[(1-methyl-1H-indol-3-yl)methylidene]acetohydrazide chemical structure, C19H18ClN3O2, CAS 863185-22-2
2-(4-Chloro-2-methylphenoxy)-N'-[(1-methyl-1H-indol-3-yl)methylidene]acetohydrazide
CAS 863185-22-2C19H18ClN3O2
2-[2-Nitro-4-(1,1,3,3-tetramethylbutyl)phenoxy]-N'-[(2-methyl-1H-indol-3-yl)methylene]acetohydrazide chemical structure, C26H32N4O4, CAS 331667-66-4
2-[2-Nitro-4-(1,1,3,3-tetramethylbutyl)phenoxy]-N'-[(2-methyl-1H-indol-3-yl)methylene]acetohydrazide
CAS 331667-66-4C26H32N4O4
(E)-N'-((1H-Indol-3-yl)methylene)-2-(o-tolyloxy)acetohydrazide chemical structure, C18H17N3O2, CAS 81111-23-1
(E)-N'-((1H-Indol-3-yl)methylene)-2-(o-tolyloxy)acetohydrazide
CAS 81111-23-1C18H17N3O2
2-(2-tert-Butylphenoxy)-N'-(1H-indol-3-ylmethylene)acetohydrazide chemical structure, C21H23N3O2, CAS 464888-21-9
2-(2-tert-Butylphenoxy)-N'-(1H-indol-3-ylmethylene)acetohydrazide
CAS 464888-21-9C21H23N3O2
2-(2,4-Dichlorophenoxy)-N'-(1H-indol-3-ylmethylene)acetohydrazide chemical structure, C17H13Cl2N3O2, CAS 316154-24-2
2-(2,4-Dichlorophenoxy)-N'-(1H-indol-3-ylmethylene)acetohydrazide
CAS 316154-24-2C17H13Cl2N3O2
2-(2-Bromo-4-methoxyphenoxy)-N'-({6-nitro-2-methyl-1H-indol-3-yl}methylene)acetohydrazide chemical structure, C19H17BrN4O5, CAS 352523-47-8
2-(2-Bromo-4-methoxyphenoxy)-N'-({6-nitro-2-methyl-1H-indol-3-yl}methylene)acetohydrazide
CAS 352523-47-8C19H17BrN4O5
2-(2-Chlorophenoxy)-N'-(1H-indol-3-ylmethylene)acetohydrazide chemical structure, C17H14ClN3O2, CAS 81111-25-3
2-(2-Chlorophenoxy)-N'-(1H-indol-3-ylmethylene)acetohydrazide
CAS 81111-25-3C17H14ClN3O2
(E)-N'-((1H-Indol-3-yl)methylene)-2-(4-bromophenoxy)acetohydrazide chemical structure, C17H14BrN3O2, CAS 299934-52-4
(E)-N'-((1H-Indol-3-yl)methylene)-2-(4-bromophenoxy)acetohydrazide
CAS 299934-52-4C17H14BrN3O2
2-(2,3-Dichlorophenoxy)-N'-(1H-indol-3-ylmethylene)acetohydrazide chemical structure, C17H13Cl2N3O2, CAS 765310-79-0
2-(2,3-Dichlorophenoxy)-N'-(1H-indol-3-ylmethylene)acetohydrazide
CAS 765310-79-0C17H13Cl2N3O2
(E)-Ethyl 6-chloro-3-((2-(2-(2-chlorophenoxy)acetyl)hydrazono)methyl)-1H-indole-2-carboxylate chemical structure, C20H17Cl2N3O4, CAS 2361143-02-2
(E)-Ethyl 6-chloro-3-((2-(2-(2-chlorophenoxy)acetyl)hydrazono)methyl)-1H-indole-2-carboxylate
CAS 2361143-02-2C20H17Cl2N3O4