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Murcko scaffold

Ring system with 3 rings and 22 atoms

28 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 22
Chemicals: 28
With full pages: 11

Scaffold SMILES

O=C(CCn1cnc2ccccc21)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CCn1cnc2ccccc21)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

3-(Benzimidazol-1-yl)-N-(1-phenylethylideneamino)propanamide chemical structure, C18H18N4O

3-(Benzimidazol-1-yl)-N-(1-phenylethylideneamino)propanamide

C₁₈H₁₈N₄O

3-(1H-Benzimidazol-1-yl)-N'-(2-ethoxybenzylidene)propanohydrazide chemical structure, C19H20N4O2, CAS 452089-76-8

3-(1H-Benzimidazol-1-yl)-N'-(2-ethoxybenzylidene)propanohydrazide

CAS 452089-76-8C₁₉H₂₀N₄O₂

(Z)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-ethoxybenzylidene)propanehydrazide chemical structure, C19H20N4O2, CAS 452090-06-1

(Z)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-ethoxybenzylidene)propanehydrazide

CAS 452090-06-1C₁₉H₂₀N₄O₂

3-(1H-Benzimidazol-1-yl)-N'-[(1Z)-1-phenylethylidene]propanehydrazide chemical structure, C18H18N4O, CAS 4833-57-2

3-(1H-Benzimidazol-1-yl)-N'-[(1Z)-1-phenylethylidene]propanehydrazide

CAS 4833-57-2C₁₈H₁₈N₄O

(Z)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(1-(4-ethoxyphenyl)ethylidene)propanehydrazide chemical structure, C20H22N4O2, CAS 374630-39-4

(Z)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(1-(4-ethoxyphenyl)ethylidene)propanehydrazide

CAS 374630-39-4C₂₀H₂₂N₄O₂

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-benzylidenepropanehydrazide chemical structure, C17H16N4O, CAS 518018-60-5

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-benzylidenepropanehydrazide

CAS 518018-60-5C₁₇H₁₆N₄O

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-(dimethylamino)benzylidene)propanehydrazide chemical structure, C19H21N5O, CAS 518018-63-8

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-(dimethylamino)benzylidene)propanehydrazide

CAS 518018-63-8C₁₉H₂₁N₅O

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(3-methoxybenzylidene)propanehydrazide chemical structure, C18H18N4O2, CAS 518018-77-4

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(3-methoxybenzylidene)propanehydrazide

CAS 518018-77-4C₁₈H₁₈N₄O₂

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(2-methoxybenzylidene)propanehydrazide chemical structure, C18H18N4O2, CAS 518018-72-9

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(2-methoxybenzylidene)propanehydrazide

CAS 518018-72-9C₁₈H₁₈N₄O₂

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-isopropylbenzylidene)propanehydrazide chemical structure, C20H22N4O, CAS 518018-75-2

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-isopropylbenzylidene)propanehydrazide

CAS 518018-75-2C₂₀H₂₂N₄O

(E)-Methyl 4-((2-(3-(1H-benzo[d]imidazol-1-yl)propanoyl)hydrazono)methyl)benzoate chemical structure, C19H18N4O3, CAS 374630-34-9

(E)-Methyl 4-((2-(3-(1H-benzo[d]imidazol-1-yl)propanoyl)hydrazono)methyl)benzoate

CAS 374630-34-9C₁₉H₁₈N₄O₃

3-(Benzimidazol-1-yl)-N-[(E)-(4-methoxyphenyl)methylideneamino]propanamide chemical structure, C18H18N4O2, CAS 518018-61-6

3-(Benzimidazol-1-yl)-N-[(E)-(4-methoxyphenyl)methylideneamino]propanamide

CAS 518018-61-6C₁₈H₁₈N₄O₂

3-(1H-Benzimidazol-1-yl)-N'-(1-phenylethylidene)propanohydrazide chemical structure, C18H18N4O

3-(1H-Benzimidazol-1-yl)-N'-(1-phenylethylidene)propanohydrazide

C₁₈H₁₈N₄O

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-fluorobenzylidene)propanehydrazide chemical structure, C17H15FN4O, CAS 518018-59-2

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-fluorobenzylidene)propanehydrazide

CAS 518018-59-2C₁₇H₁₅FN₄O

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(3-nitrobenzylidene)propanehydrazide chemical structure, C17H15N5O3, CAS 518018-67-2

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(3-nitrobenzylidene)propanehydrazide

CAS 518018-67-2C₁₇H₁₅N₅O₃

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-nitrobenzylidene)propanehydrazide chemical structure, C17H15N5O3, CAS 401607-35-0

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-nitrobenzylidene)propanehydrazide

CAS 401607-35-0C₁₇H₁₅N₅O₃

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(3-hydroxybenzylidene)-2-methylpropanehydrazide chemical structure, C18H18N4O2, CAS 374630-49-6

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(3-hydroxybenzylidene)-2-methylpropanehydrazide

CAS 374630-49-6C₁₈H₁₈N₄O₂

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(3,4-dimethoxybenzylidene)propanehydrazide chemical structure, C19H20N4O3, CAS 518018-74-1

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(3,4-dimethoxybenzylidene)propanehydrazide

CAS 518018-74-1C₁₉H₂₀N₄O₃

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(3-methoxybenzylidene)-2-methylpropanehydrazide chemical structure, C19H20N4O2, CAS 518018-87-6

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(3-methoxybenzylidene)-2-methylpropanehydrazide

CAS 518018-87-6C₁₉H₂₀N₄O₂

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-isopropylbenzylidene)-2-methylpropanehydrazide chemical structure, C21H24N4O, CAS 374630-43-0

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-isopropylbenzylidene)-2-methylpropanehydrazide

CAS 374630-43-0C₂₁H₂₄N₄O

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-benzylidene-2-methylpropanehydrazide chemical structure, C18H18N4O, CAS 518018-78-5

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-benzylidene-2-methylpropanehydrazide

CAS 518018-78-5C₁₈H₁₈N₄O

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-methoxybenzylidene)-2-methylpropanehydrazide chemical structure, C19H20N4O2, CAS 452089-79-1

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(4-methoxybenzylidene)-2-methylpropanehydrazide

CAS 452089-79-1C₁₉H₂₀N₄O₂

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(2-methoxybenzylidene)-2-methylpropanehydrazide chemical structure, C19H20N4O2, CAS 374630-53-2

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(2-methoxybenzylidene)-2-methylpropanehydrazide

CAS 374630-53-2C₁₉H₂₀N₄O₂

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(2-hydroxybenzylidene)propanehydrazide chemical structure, C17H16N4O2, CAS 518018-62-7

(E)-3-(1H-Benzo[d]imidazol-1-yl)-N'-(2-hydroxybenzylidene)propanehydrazide

CAS 518018-62-7C₁₇H₁₆N₄O₂