Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 20 atoms

66 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 20
Chemicals: 66
With full pages: 5

Scaffold SMILES

c1ccc(-n2cnnc2-c2c[nH]c3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(-n2cnnc2-c2c[nH]c3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 66 chemicals

Methyl 2-((4-(4-ethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetate chemical structure, C21H20N4O3S, CAS 730991-82-9

Methyl 2-((4-(4-ethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetate

CAS 730991-82-9C₂₁H₂₀N₄O₃S

2-((4-(4-Ethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C20H19N5O2S, CAS 781620-34-6

2-((4-(4-Ethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide

CAS 781620-34-6C₂₀H₁₉N₅O₂S

Ethyl 2-{[4-(4-fluorophenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}butanoate chemical structure, C22H21FN4O2S, CAS 946359-85-9

Ethyl 2-{[4-(4-fluorophenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}butanoate

CAS 946359-85-9C₂₂H₂₁FN₄O₂S

2-((4-(2,5-Dimethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N,N-dimethyl-3-oxobutanamide chemical structure, C24H25N5O4S, CAS 852167-49-8

2-((4-(2,5-Dimethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N,N-dimethyl-3-oxobutanamide

CAS 852167-49-8C₂₄H₂₅N₅O₄S

3-(4-(3-Methoxyphenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C18H16N4OS, CAS 852145-37-0

3-(4-(3-Methoxyphenyl)-5-(methylthio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852145-37-0C₁₈H₁₆N₄OS

Methyl 2-{[5-(1H-indol-3-yl)-4-(3-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}butanoate chemical structure, C22H22N4O3S, CAS 946206-21-9

Methyl 2-{[5-(1H-indol-3-yl)-4-(3-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}butanoate

CAS 946206-21-9C₂₂H₂₂N₄O₃S

3-(5-(sec-Butylthio)-4-(4-ethoxyphenyl)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C22H24N4OS, CAS 946235-76-3

3-(5-(sec-Butylthio)-4-(4-ethoxyphenyl)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 946235-76-3C₂₂H₂₄N₄OS

Ethyl 2-((4-(2,5-dimethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)butanoate chemical structure, C24H26N4O4S, CAS 919867-94-0

Ethyl 2-((4-(2,5-dimethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)butanoate

CAS 919867-94-0C₂₄H₂₆N₄O₄S

Diethyl 2-((4-(4-fluorophenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)malonate chemical structure, C23H21FN4O4S, CAS 852167-75-0

Diethyl 2-((4-(4-fluorophenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)malonate

CAS 852167-75-0C₂₃H₂₁FN₄O₄S

3-((4-(2,5-Dimethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)pentane-2,4-dione chemical structure, C23H22N4O4S, CAS 852167-50-1

3-((4-(2,5-Dimethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)pentane-2,4-dione

CAS 852167-50-1C₂₃H₂₂N₄O₄S

3-[4-(2,5-Dimethoxyphenyl)-5-(propylsulfanyl)-4H-1,2,4-triazol-3-yl]-1H-indole chemical structure, C21H22N4O2S, CAS 946275-67-8

3-[4-(2,5-Dimethoxyphenyl)-5-(propylsulfanyl)-4H-1,2,4-triazol-3-yl]-1H-indole

CAS 946275-67-8C₂₁H₂₂N₄O₂S

3-(5-(sec-Butylthio)-4-(4-fluorophenyl)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C20H19FN4S, CAS 946276-16-0

3-(5-(sec-Butylthio)-4-(4-fluorophenyl)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 946276-16-0C₂₀H₁₉FN₄S

3-(4-(4-Fluorophenyl)-5-(isopentylthio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C21H21FN4S, CAS 946359-45-1

3-(4-(4-Fluorophenyl)-5-(isopentylthio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 946359-45-1C₂₁H₂₁FN₄S

Ethyl 2-(2-((5-(1H-indol-3-yl)-4-(3-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamido)acetate chemical structure, C23H23N5O4S, CAS 852145-49-4

Ethyl 2-(2-((5-(1H-indol-3-yl)-4-(3-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamido)acetate

CAS 852145-49-4C₂₃H₂₃N₅O₄S

Methyl 2-((4-(2,5-dimethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)propanoate chemical structure, C22H22N4O4S, CAS 852167-48-7

Methyl 2-((4-(2,5-dimethoxyphenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)propanoate

CAS 852167-48-7C₂₂H₂₂N₄O₄S

Sodium 5-(1H-indol-3-yl)-4-phenyl-4H-1,2,4-triazole-3-thiolate chemical structure, C16H11N4NaS, CAS 1007016-46-7

Sodium 5-(1H-indol-3-yl)-4-phenyl-4H-1,2,4-triazole-3-thiolate

CAS 1007016-46-7C₁₆H₁₁N₄NaS

3-[4-(4-Methoxyphenyl)-5-(propylsulfanyl)-4H-1,2,4-triazol-3-yl]-1H-indole chemical structure, C20H20N4OS, CAS 946377-54-4

3-[4-(4-Methoxyphenyl)-5-(propylsulfanyl)-4H-1,2,4-triazol-3-yl]-1H-indole

CAS 946377-54-4C₂₀H₂₀N₄OS

Methyl 2-((4-(4-fluorophenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)propanoate chemical structure, C20H17FN4O2S, CAS 852167-74-9

Methyl 2-((4-(4-fluorophenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)propanoate

CAS 852167-74-9C₂₀H₁₇FN₄O₂S

Ethyl 2-(2-((5-(1H-indol-3-yl)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamido)acetate chemical structure, C23H23N5O4S, CAS 852167-23-8

Ethyl 2-(2-((5-(1H-indol-3-yl)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamido)acetate

CAS 852167-23-8C₂₃H₂₃N₅O₄S

2-((5-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C19H17N5O2S, CAS 852145-66-5

2-((5-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide

CAS 852145-66-5C₁₉H₁₇N₅O₂S

3-(5-(Isopentylthio)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C22H24N4OS, CAS 946377-57-7

3-(5-(Isopentylthio)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 946377-57-7C₂₂H₂₄N₄OS

Ethyl 2-(2-((4-(4-fluorophenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamido)acetate chemical structure, C22H20FN5O3S, CAS 852167-66-9

Ethyl 2-(2-((4-(4-fluorophenyl)-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamido)acetate

CAS 852167-66-9C₂₂H₂₀FN₅O₃S

2-((5-(1H-Indol-3-yl)-4-(3-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C19H17N5O2S, CAS 852145-45-0

2-((5-(1H-Indol-3-yl)-4-(3-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide

CAS 852145-45-0C₁₉H₁₇N₅O₂S

3-(5-(Butylthio)-4-(2,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C22H24N4O2S, CAS 946235-60-5

3-(5-(Butylthio)-4-(2,5-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 946235-60-5C₂₂H₂₄N₄O₂S