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Murcko scaffold

Ring system with 4 rings and 22 atoms

17 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 17
With full pages: 4

Scaffold SMILES

O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

SB 216763 chemical structure, C19H12Cl2N2O2, CAS 280744-09-4

CAS 280744-09-4C₁₉H₁₂Cl₂N₂O₂

3-(4-Chlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione chemical structure, C19H13ClN2O2, CAS 125313-99-7

3-(4-Chlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS 125313-99-7C₁₉H₁₃ClN₂O₂

Iron oxide, spent chemical structure, C19H15N3O2, CAS 125314-13-8

Iron oxide, spent

CAS 125314-13-8C₁₉H₁₅N₃O₂

3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione chemical structure, C21H18N2O5, CAS 863223-52-3

3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione

CAS 863223-52-3C₂₁H₁₈N₂O₅

3-[3-(2,3-Dihydroxy-propylamino)-phenyl]-4-(5-fluoro-1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione chemical structure, C22H20FN3O4, CAS 396091-16-0

3-[3-(2,3-Dihydroxy-propylamino)-phenyl]-4-(5-fluoro-1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione

CAS 396091-16-0C₂₂H₂₀FN₃O₄

3-(3-Chlorophenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione chemical structure, C20H15ClN2O2, CAS 1021953-05-8

3-(3-Chlorophenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS 1021953-05-8C₂₀H₁₅ClN₂O₂

1-Methyl-3-(2-methyl-1H-indol-3-yl)-4-phenyl-1H-pyrrole-2,5-dione chemical structure, C20H16N2O2, CAS 1021953-02-5

1-Methyl-3-(2-methyl-1H-indol-3-yl)-4-phenyl-1H-pyrrole-2,5-dione

CAS 1021953-02-5C₂₀H₁₆N₂O₂

3-(2,6-Dimethylphenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione chemical structure, C22H20N2O2, CAS 1021953-04-7

3-(2,6-Dimethylphenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS 1021953-04-7C₂₂H₂₀N₂O₂

3-(2,4-Dichlorophenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione chemical structure, C20H14Cl2N2O2, CAS 1021953-06-9

3-(2,4-Dichlorophenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS 1021953-06-9C₂₀H₁₄Cl₂N₂O₂

3-(2,5-Dimethoxyphenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione chemical structure, C22H20N2O4, CAS 1021953-10-5

3-(2,5-Dimethoxyphenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS 1021953-10-5C₂₂H₂₀N₂O₄

3-(4-Ethenylphenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione chemical structure, C22H18N2O2, CAS 1021953-13-8

3-(4-Ethenylphenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS 1021953-13-8C₂₂H₁₈N₂O₂

3-(4-Fluorophenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione chemical structure, C20H15FN2O2, CAS 1021953-14-9

3-(4-Fluorophenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS 1021953-14-9C₂₀H₁₅FN₂O₂

3-(4-Acetylphenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione chemical structure, C22H18N2O3, CAS 1021953-03-6

3-(4-Acetylphenyl)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS 1021953-03-6C₂₂H₁₈N₂O₃

Aqabamycin G chemical structure, C18H11N3O5, CAS 1252019-82-1

CAS 1252019-82-1C₁₈H₁₁N₃O₅

3-(4-Acetyl-phenyl)-4-(2-methyl-1H-indol-3-yl)-pyrrole-2,5-dione chemical structure, C21H16N2O3, CAS 1613633-78-5

3-(4-Acetyl-phenyl)-4-(2-methyl-1H-indol-3-yl)-pyrrole-2,5-dione

CAS 1613633-78-5C₂₁H₁₆N₂O₃

3-(2-Methyl-1H-indol-3-yl)-4-phenyl-1H-pyrrole-2,5-dione chemical structure, C19H14N2O2, CAS 1613633-74-1

3-(2-Methyl-1H-indol-3-yl)-4-phenyl-1H-pyrrole-2,5-dione

CAS 1613633-74-1C₁₉H₁₄N₂O₂

3-(4-Acetylphenyl)-4-(1,2-dimethyl-1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione chemical structure, C23H20N2O3, CAS 1613633-79-6

3-(4-Acetylphenyl)-4-(1,2-dimethyl-1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione

CAS 1613633-79-6C₂₃H₂₀N₂O₃