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Murcko scaffold

Ring system with 4 rings and 23 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
9
With full pages
9
Scaffold SMILES

S=c1[nH]nc(-c2ccccc2)n1N=Cc1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]nc(-c2ccccc2)n1N=Cc1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

4-{[(1H-Indol-3-yl)methylidene]amino}-5-phenyl-4H-1,2,4-triazole-3-thiol chemical structure, C17H13N5S, CAS 418802-74-1
4-{[(1H-Indol-3-yl)methylidene]amino}-5-phenyl-4H-1,2,4-triazole-3-thiol
CAS 418802-74-1C17H13N5S
5-(4-F-PH)-4-((1H-Indol-3-ylmethylene)amino)-4H-1,2,4-triazol-3-yl hydrosulfide chemical structure, C17H12FN5S, CAS 676243-77-9
5-(4-F-PH)-4-((1H-Indol-3-ylmethylene)amino)-4H-1,2,4-triazol-3-yl hydrosulfide
CAS 676243-77-9C17H12FN5S
5-(2-CL-PH)-4-((1H-Indol-3-ylmethylene)amino)-4H-1,2,4-triazol-3-yl hydrosulfide chemical structure, C17H12ClN5S, CAS 478254-33-0
5-(2-CL-PH)-4-((1H-Indol-3-ylmethylene)amino)-4H-1,2,4-triazol-3-yl hydrosulfide
CAS 478254-33-0C17H12ClN5S
4-(((1H-Indol-3-yl)methylene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione chemical structure, C17H12FN5S, CAS 676151-26-1
4-(((1H-Indol-3-yl)methylene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione
CAS 676151-26-1C17H12FN5S
5-(3-CL-PH)-4-((1H-Indol-3-ylmethylene)amino)-4H-1,2,4-triazol-3-yl hydrosulfide chemical structure, C17H12ClN5S, CAS 478255-23-1
5-(3-CL-PH)-4-((1H-Indol-3-ylmethylene)amino)-4H-1,2,4-triazol-3-yl hydrosulfide
CAS 478255-23-1C17H12ClN5S
4-((1H-Indol-3-ylmethylene)amino)-5-(4-methoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C18H15N5OS, CAS 478253-61-1
4-((1H-Indol-3-ylmethylene)amino)-5-(4-methoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 478253-61-1C18H15N5OS
4-((1H-Indol-3-ylmethylene)amino)-5-(3-methylphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C18H15N5S, CAS 478256-18-7
4-((1H-Indol-3-ylmethylene)amino)-5-(3-methylphenyl)-4H-1,2,4-triazole-3-thiol
CAS 478256-18-7C18H15N5S
4-((1H-Indol-3-ylmethylene)amino)-5-(2-methoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C18H15N5OS, CAS 478257-15-7
4-((1H-Indol-3-ylmethylene)amino)-5-(2-methoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 478257-15-7C18H15N5OS
4-((1H-Indol-3-ylmethylene)amino)-5-(3-methoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C18H15N5OS, CAS 613249-15-3
4-((1H-Indol-3-ylmethylene)amino)-5-(3-methoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 613249-15-3C18H15N5OS