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Murcko scaffold

3,4-Dihydro-2H-quinolin-1-yl(pyridin-3-yl)methanone scaffold

40 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
40
With full pages
3
Scaffold SMILES

O=C(c1cccnc1)N1CCCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3,4-Dihydro-2H-quinolin-1-yl(pyridin-3-yl)methanone page
Murcko scaffold O=C(c1cccnc1)N1CCCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

Nicainoprol chemical structure, C21H27N3O3, CAS 76252-06-7
Nicainoprol
CAS 76252-06-7C21H27N3O3
(5-Bromopyridin-3-yl)(3,4-dihydroquinolin-1(2H)-yl)methanone chemical structure, C15H13BrN2O, CAS 370852-38-3
(5-Bromopyridin-3-yl)(3,4-dihydroquinolin-1(2H)-yl)methanone
CAS 370852-38-3C15H13BrN2O
3,4-Dihydro-2H-quinolin-1-yl(pyridin-3-yl)methanone chemical structure, C15H14N2O, CAS 346724-18-3
3,4-Dihydro-2H-quinolin-1-yl(pyridin-3-yl)methanone
CAS 346724-18-3C15H14N2O
1,2,3,4-Tetrahydro-1-(3-pyridylcarbonyl)quinolin-8-ol chemical structure, C15H14N2O2, CAS 77771-22-3
1,2,3,4-Tetrahydro-1-(3-pyridylcarbonyl)quinolin-8-ol
CAS 77771-22-3C15H14N2O2
(6-Methyl-3,4-dihydro-2H-quinolin-1-yl)-pyridin-3-ylmethanone chemical structure, C16H16N2O, CAS 1023828-93-4
(6-Methyl-3,4-dihydro-2H-quinolin-1-yl)-pyridin-3-ylmethanone
CAS 1023828-93-4C16H16N2O
(2-Chloro-3-pyridinyl)[3,4-dihydro-1(2H)-quinolinyl]methanone chemical structure, C15H13ClN2O, CAS 545340-46-3
(2-Chloro-3-pyridinyl)[3,4-dihydro-1(2H)-quinolinyl]methanone
CAS 545340-46-3C15H13ClN2O
(6-Amino-3,4-dihydroquinolin-1(2H)-yl)(pyridin-3-yl)methanone chemical structure, C15H15N3O, CAS 927996-15-4
(6-Amino-3,4-dihydroquinolin-1(2H)-yl)(pyridin-3-yl)methanone
CAS 927996-15-4C15H15N3O
(7-Amino-3,4-dihydroquinolin-1(2H)-yl)(pyridin-3-yl)methanone chemical structure, C15H15N3O, CAS 927996-52-9
(7-Amino-3,4-dihydroquinolin-1(2H)-yl)(pyridin-3-yl)methanone
CAS 927996-52-9C15H15N3O
(6-Methoxy-3,4-dihydro-2H-quinolin-1-yl)pyridin-3-ylmethanone hydrochloride chemical structure, C16H17ClN2O2, CAS 7498-45-5
(6-Methoxy-3,4-dihydro-2H-quinolin-1-yl)pyridin-3-ylmethanone hydrochloride
CAS 7498-45-5C16H17ClN2O2
1-(6-Chloropyridine-3-carbonyl)-6-methyl-1,2,3,4-tetrahydroquinoline chemical structure, C16H15ClN2O, CAS 1016787-17-9
1-(6-Chloropyridine-3-carbonyl)-6-methyl-1,2,3,4-tetrahydroquinoline
CAS 1016787-17-9C16H15ClN2O
6-Methyl-1-[2-(methylsulfanyl)pyridine-3-carbonyl]-1,2,3,4-tetrahydroquinoline chemical structure, C17H18N2OS, CAS 1197632-16-8
6-Methyl-1-[2-(methylsulfanyl)pyridine-3-carbonyl]-1,2,3,4-tetrahydroquinoline
CAS 1197632-16-8C17H18N2OS
1-[2-(Methylsulfanyl)pyridine-3-carbonyl]-1,2,3,4-tetrahydroquinoline chemical structure, C16H16N2OS, CAS 1181523-56-7
1-[2-(Methylsulfanyl)pyridine-3-carbonyl]-1,2,3,4-tetrahydroquinoline
CAS 1181523-56-7C16H16N2OS
Methyl 1-[2-(methylsulfanyl)pyridine-3-carbonyl]-1,2,3,4-tetrahydroquinoline-5-carboxylate chemical structure, C18H18N2O3S, CAS 1111460-74-2
Methyl 1-[2-(methylsulfanyl)pyridine-3-carbonyl]-1,2,3,4-tetrahydroquinoline-5-carboxylate
CAS 1111460-74-2C18H18N2O3S
1-(6-Chloropyridine-3-carbonyl)-8-methoxy-1,2,3,4-tetrahydroquinoline chemical structure, C16H15ClN2O2, CAS 1184037-04-4
1-(6-Chloropyridine-3-carbonyl)-8-methoxy-1,2,3,4-tetrahydroquinoline
CAS 1184037-04-4C16H15ClN2O2
(5,7-Difluoro-3,4-dihydro-2H-quinolin-1-yl)-(2-methylsulfanylpyridin-3-yl)methanone chemical structure, C16H14F2N2OS, CAS 1197665-22-7
(5,7-Difluoro-3,4-dihydro-2H-quinolin-1-yl)-(2-methylsulfanylpyridin-3-yl)methanone
CAS 1197665-22-7C16H14F2N2OS
1-(6-Chloropyridine-3-carbonyl)-7-fluoro-1,2,3,4-tetrahydroquinoline chemical structure, C15H12ClFN2O, CAS 1210335-51-5
1-(6-Chloropyridine-3-carbonyl)-7-fluoro-1,2,3,4-tetrahydroquinoline
CAS 1210335-51-5C15H12ClFN2O
7-Fluoro-1-[2-(methylsulfanyl)pyridine-3-carbonyl]-1,2,3,4-tetrahydroquinoline chemical structure, C16H15FN2OS, CAS 1209753-75-2
7-Fluoro-1-[2-(methylsulfanyl)pyridine-3-carbonyl]-1,2,3,4-tetrahydroquinoline
CAS 1209753-75-2C16H15FN2OS
1-(5,6-Dichloropyridine-3-carbonyl)-8-methoxy-1,2,3,4-tetrahydroquinoline chemical structure, C16H14Cl2N2O2, CAS 1223492-15-6
1-(5,6-Dichloropyridine-3-carbonyl)-8-methoxy-1,2,3,4-tetrahydroquinoline
CAS 1223492-15-6C16H14Cl2N2O2
1-(5,6-Dichloropyridine-3-carbonyl)-5,7-difluoro-1,2,3,4-tetrahydroquinoline chemical structure, C15H10Cl2F2N2O, CAS 1223636-75-6
1-(5,6-Dichloropyridine-3-carbonyl)-5,7-difluoro-1,2,3,4-tetrahydroquinoline
CAS 1223636-75-6C15H10Cl2F2N2O
1-(5,6-Dichloropyridine-3-carbonyl)-6-(propan-2-yl)-1,2,3,4-tetrahydroquinoline chemical structure, C18H18Cl2N2O, CAS 1222903-47-0
1-(5,6-Dichloropyridine-3-carbonyl)-6-(propan-2-yl)-1,2,3,4-tetrahydroquinoline
CAS 1222903-47-0C18H18Cl2N2O
1-[2-(Methylsulfanyl)pyridine-3-carbonyl]-6-(propan-2-yl)-1,2,3,4-tetrahydroquinoline chemical structure, C19H22N2OS, CAS 1223350-04-6
1-[2-(Methylsulfanyl)pyridine-3-carbonyl]-6-(propan-2-yl)-1,2,3,4-tetrahydroquinoline
CAS 1223350-04-6C19H22N2OS
1-(6-Chloropyridine-3-carbonyl)-4-methyl-1,2,3,4-tetrahydroquinoline chemical structure, C16H15ClN2O, CAS 1222913-32-7
1-(6-Chloropyridine-3-carbonyl)-4-methyl-1,2,3,4-tetrahydroquinoline
CAS 1222913-32-7C16H15ClN2O
8-Fluoro-6-methyl-1-[2-(methylsulfanyl)pyridine-3-carbonyl]-1,2,3,4-tetrahydroquinoline chemical structure, C17H17FN2OS, CAS 1223011-86-6
8-Fluoro-6-methyl-1-[2-(methylsulfanyl)pyridine-3-carbonyl]-1,2,3,4-tetrahydroquinoline
CAS 1223011-86-6C17H17FN2OS
1-(2-Chloro-6-methylpyridine-3-carbonyl)-5,7-difluoro-1,2,3,4-tetrahydroquinoline chemical structure, C16H13ClF2N2O, CAS 1223747-17-8
1-(2-Chloro-6-methylpyridine-3-carbonyl)-5,7-difluoro-1,2,3,4-tetrahydroquinoline
CAS 1223747-17-8C16H13ClF2N2O